SUPERFAMILY 1.75 HMM library and genome assignments server

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LIM domain family

SCOP classification
Root:   SCOP hierarchy in SUPERFAMILY [ 0] (11)
Class:   Small proteins [ 56992] (90)
Fold:   Glucocorticoid receptor-like (DNA-binding domain) [ 57715]
Superfamily:   Glucocorticoid receptor-like (DNA-binding domain) [ 57716] (18)
Family:   LIM domain [ 57736] (18)


Family statistics
Genomes (0) Uniprot 2018_03 genome PDB chains (SCOP 1.75)
Domains 0 0 0
Proteins 0 0 0


Enzyme Commission (EC)

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show details)
EC termFDR (all)SDEO levelAnnotation (direct or inherited)
Enzyme Commission (EC)Protein-serine/threonine kinases0Moderately InformativeDirect
Enzyme Commission (EC)Non-specific serine/threonine protein kinase0InformativeDirect

Document: EC annotation of SCOP domains

Human Phenotype (HP)

(show details)
HP termFDR (all)SDHP levelAnnotation (direct or inherited)
Phenotypic Abnormality (PA)Abnormality of metabolism/homeostasis0.05589Least InformativeInherited
Phenotypic Abnormality (PA)Abnormality of the cardiovascular system0.3385Least InformativeInherited
Phenotypic Abnormality (PA)Abnormality of the musculature0.4022Least InformativeInherited
Phenotypic Abnormality (PA)Abnormality of limbs0.4776Least InformativeInherited
Phenotypic Abnormality (PA)Abnormality of connective tissue0.0262Moderately InformativeInherited
Phenotypic Abnormality (PA)Abnormal heart morphology0.0508Moderately InformativeInherited
Phenotypic Abnormality (PA)Abnormal cardiovascular system physiology0.06428Moderately InformativeInherited
Phenotypic Abnormality (PA)Abnormal circulating metabolite concentration0.1616Moderately InformativeInherited
Phenotypic Abnormality (PA)Abnormal skeletal muscle morphology0.1629Moderately InformativeInherited
Phenotypic Abnormality (PA)Abnormality of the lower limb0.409Moderately InformativeInherited
Phenotypic Abnormality (PA)Abnormal myocardium morphology0.0005483InformativeDirect
Phenotypic Abnormality (PA)Abnormal circulating protein level0.0006161InformativeDirect
Phenotypic Abnormality (PA)Abnormal adipose tissue morphology0.009453InformativeInherited
Phenotypic Abnormality (PA)Arrhythmia0.01389InformativeInherited
Phenotypic Abnormality (PA)Abnormality of the musculature of the limbs0.07947InformativeInherited
Phenotypic Abnormality (PA)Sudden cardiac death0.00005361Highly InformativeDirect
Phenotypic Abnormality (PA)Lipodystrophy0.0001141Highly InformativeDirect
Phenotypic Abnormality (PA)Abnormality of the musculature of the lower limbs0.0008793Highly InformativeDirect

Document: HP annotation of SCOP domains

Mouse Phenotype (MP)

(show details)
MP termFDR (all)SDMP levelAnnotation (direct or inherited)
Mammalian Phenotype (MP)cardiovascular system phenotype0.01779Least InformativeInherited
Mammalian Phenotype (MP)abnormal muscle physiology0.007646Moderately InformativeInherited
Mammalian Phenotype (MP)abnormal heart morphology0.03582Moderately InformativeInherited
Mammalian Phenotype (MP)abnormal cardiovascular system physiology0.2197Moderately InformativeInherited
Mammalian Phenotype (MP)respiratory system phenotype0.3282Moderately InformativeInherited
Mammalian Phenotype (MP)abnormal blood vessel morphology0.8368Moderately InformativeInherited
Mammalian Phenotype (MP)abnormal response to injury0.0008945InformativeDirect
Mammalian Phenotype (MP)impaired muscle contractility0.003042InformativeInherited
Mammalian Phenotype (MP)abnormal cardiac muscle contractility0.01937InformativeInherited
Mammalian Phenotype (MP)abnormal heart left ventricle morphology0.0004976Highly InformativeDirect
Mammalian Phenotype (MP)dilated heart0.03105Highly InformativeInherited
Mammalian Phenotype (MP)abnormal lung size0.09436Highly InformativeInherited

Document: MP annotation of SCOP domains

Worm Phenotype (WP)

(show details)
WP termFDR (all)SDWP levelAnnotation (direct or inherited)
Worm Phenotype (WP)cell physiology variant0.01888Least InformativeInherited
Worm Phenotype (WP)organism behavior variant0.0253Least InformativeInherited
Worm Phenotype (WP)organism metabolism processing variant0.03312Least InformativeInherited
Worm Phenotype (WP)protein expression variant0.001022Moderately InformativeInherited
Worm Phenotype (WP)cell type morphology variant0.1832Moderately InformativeInherited
Worm Phenotype (WP)cell homeostasis metabolism variant0.3723Moderately InformativeInherited
Worm Phenotype (WP)mitochondria morphology variant0.00000004273InformativeDirect
Worm Phenotype (WP)body wall muscle sarcomere morphology variant0.00000007983InformativeDirect
Worm Phenotype (WP)muscle cell physiology variant0.0000008856InformativeDirect
Worm Phenotype (WP)level of protein expression variant0.000003531InformativeDirect
Worm Phenotype (WP)cell component localization variant0.001333InformativeInherited
Worm Phenotype (WP)protein metabolism variant0.005107InformativeInherited
Worm Phenotype (WP)muscle cell attachment variant0.00000001056Highly InformativeDirect
Worm Phenotype (WP)protein expression reduced0.0000008294Highly InformativeDirect
Worm Phenotype (WP)protein degradation variant0.000168Highly InformativeDirect

Document: WP annotation of SCOP domains

Fly Anatomy (FA)

(show details) Document: FA annotation of SCOP domains

Zebrafish Anatomy (ZA)

(show details)
ZA termFDR (all)SDZA levelAnnotation (direct or inherited)
Zebrafish Anatomy (ZA)anatomical cluster0.2398Least InformativeInherited
Zebrafish Anatomy (ZA)cavitated compound organ0.3521Least InformativeInherited
Zebrafish Anatomy (ZA)cardiovascular system0.03991Moderately InformativeInherited
Zebrafish Anatomy (ZA)pericardial region0.08879InformativeInherited
Zebrafish Anatomy (ZA)heart0.003589Highly InformativeInherited

Document: ZA annotation of SCOP domains

Xenopus Anatomy (XA)

(show details)
XA termFDR (all)SDXA levelAnnotation (direct or inherited)
Xenopus ANatomical entity (XAN)anatomical cluster0.001318Least InformativeInherited
Xenopus ANatomical entity (XAN)tissue0.04299Least InformativeInherited
Xenopus ANatomical entity (XAN)cavitated compound organ0.05291Least InformativeInherited
Xenopus ANatomical entity (XAN)embryo0.05636Least InformativeInherited
Xenopus ANatomical entity (XAN)trunk0.09212Least InformativeInherited
Xenopus ANatomical entity (XAN)nervous system0.1113Least InformativeInherited
Xenopus ANatomical entity (XAN)head0.1973Least InformativeInherited
Xenopus ANatomical entity (XAN)embryonic structure0.003577Moderately InformativeInherited
Xenopus ANatomical entity (XAN)multi-tissue structure0.00364Moderately InformativeInherited
Xenopus ANatomical entity (XAN)musculoskeletal system0.02053Moderately InformativeInherited
Xenopus ANatomical entity (XAN)ectoderm0.1501Moderately InformativeInherited
Xenopus ANatomical entity (XAN)viscus0.349Moderately InformativeInherited
Xenopus ANatomical entity (XAN)brain0.4554Moderately InformativeInherited
Xenopus ANatomical entity (XAN)cardiovascular system0.00002346InformativeDirect
Xenopus ANatomical entity (XAN)skeletal system0.0004108InformativeDirect
Xenopus ANatomical entity (XAN)anatomical direction0.0005994InformativeDirect
Xenopus ANatomical entity (XAN)neuroectoderm0.001287InformativeInherited
Xenopus ANatomical entity (XAN)forebrain0.01193Highly InformativeInherited
Xenopus DEvelopment stage (XDE)post-embryonic stage0.0823Least InformativeInherited
Xenopus DEvelopment stage (XDE)adult frog stage0.0007099Highly InformativeDirect

Document: XA annotation of SCOP domains

Arabidopsis Plant Ontology (AP)

(show details)
AP termFDR (all)SDAP levelAnnotation (direct or inherited)
Plant ANatomical entity (PAN)plant embryo0Least InformativeDirect
Plant ANatomical entity (PAN)megasporophyll0Least InformativeDirect
Plant ANatomical entity (PAN)microsporophyll0Least InformativeDirect
Plant ANatomical entity (PAN)sepal0Least InformativeDirect
Plant ANatomical entity (PAN)petal0Least InformativeDirect
Plant ANatomical entity (PAN)androecium0Least InformativeDirect
Plant ANatomical entity (PAN)gynoecium0Least InformativeDirect
Plant ANatomical entity (PAN)collective leaf structure0Least InformativeDirect
Plant ANatomical entity (PAN)sporangium0Least InformativeDirect
Plant ANatomical entity (PAN)microgametophyte0Least InformativeDirect
Plant ANatomical entity (PAN)pollen tube cell0.0007842InformativeDirect
Plant structure DEvelopment stage (PDE)C globular stage0Least InformativeDirect
Plant structure DEvelopment stage (PDE)L mature pollen stage0.0003341InformativeDirect
Plant structure DEvelopment stage (PDE)M germinated pollen stage0.0008805InformativeDirect

Document: AP annotation of SCOP domains

Enzyme Commission (EC)

(show details)
EC termFDR (all)SDEC levelAnnotation (direct or inherited)
Enzyme Commission (EC)Transferases0.000619Least InformativeDirect
Enzyme Commission (EC)Oxidoreductases0.04636Least InformativeInherited
Enzyme Commission (EC)Protein-serine/threonine kinases0InformativeDirect
Enzyme Commission (EC)Acting on paired donors, with incorporation or reduction of molecular oxygen. The oxygen incorporate0.0000002287InformativeDirect
Enzyme Commission (EC)With NADH or NADPH as one donor, and incorporation of one atom of oxygen0.00000000002407Highly InformativeDirect

Document: EC annotation of SCOP domains

Jump to [ Top of page · SCOP classification · Enzyme Commission (EC) · Human Phenotype (HP) · Mouse Phenotype (MP) · Worm Phenotype (WP) · Fly Anatomy (FA) · Zebrafish Anatomy (ZA) · Xenopus Anatomy (XA) · Arabidopsis Plant Ontology (AP) · Enzyme Commission (EC) ]

Internal database links

   
Superfamily level     Family level

Browse genome assignments for this superfamily. The SUPERFAMILY hidden Markov model library has been used to carry out SCOP domain assignments to all genomes at the superfamily level.


   
Superfamily level     Family level

Alignments of sequences to 127 models in this superfamily are available by clicking on the 'Alignments' icon above. PDB sequences less than 40% identical are shown by default, but any other sequence(s) may be aligned. Select PDB sequences, genome sequences, or paste in or upload your own sequences.


Superfamily level

Browse and view proteins in genomes which have different domain combinations including a Glucocorticoid receptor-like (DNA-binding domain) domain.


   
Superfamily level     Family level

Examine the distribution of domain superfamilies, or families, across the major taxonomic kingdoms or genomes within a kingdom. This gives an immediate impression of how superfamilies, or families, are restricted to certain kingdoms of life.


Jump to [ Top of page · SCOP classification · Enzyme Commission (EC) · Human Phenotype (HP) · Mouse Phenotype (MP) · Worm Phenotype (WP) · Fly Anatomy (FA) · Zebrafish Anatomy (ZA) · Xenopus Anatomy (XA) · Arabidopsis Plant Ontology (AP) · Enzyme Commission (EC) · Internal database links ]