SUPERFAMILY 1.75 HMM library and genome assignments server

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Coiled-coil domain of nucleotide exchange factor GrpE superfamily

SCOP classification
Root:   SCOP hierarchy in SUPERFAMILY [ 0] (11)
Class:   Coiled coil proteins [ 57942] (7)
Fold:   Parallel coiled-coil [ 57943] (34)
Superfamily:   Coiled-coil domain of nucleotide exchange factor GrpE [ 58014]
Families:   Coiled-coil domain of nucleotide exchange factor GrpE [ 58015]


Superfamily statistics
Genomes (3,095) Uniprot 2017_06 genome PDB chains (SCOP 1.75)
Domains 3,572 19,183 1
Proteins 3,570 19,182 1


Functional annotation
General category General
Detailed category Protein interaction

Document:
Function annotation of SCOP domain superfamilies

Gene Ontology (high-coverage)

(show details)
GO term FDR (all) SDFO level Annotation (direct or inherited)
Molecular Function (MF) binding 0.0008772 Least Informative Direct
Cellular Component (CC) cytoplasmic part 0.00000007195 Least Informative Direct
Cellular Component (CC) intracellular membrane-bounded organelle 0.0000185 Least Informative Direct
Cellular Component (CC) intracellular organelle part 0.345 Least Informative Inherited
Cellular Component (CC) intracellular organelle lumen 0.1619 Moderately Informative Inherited

Document: GO annotation of SCOP domains

UniProtKB KeyWords (KW)

(show details)
KW termFDR (all)SDKW levelAnnotation (direct or inherited)
Biological processStress response0InformativeDirect
Cellular componentCytoplasm0Least InformativeDirect
Post-translational modificationChaperone0InformativeDirect

Document: KW annotation of SCOP domains

Jump to [ Top of page · SCOP classification · Functional annotation · Gene Ontology (high-coverage) · UniProtKB KeyWords (KW) ]

Internal database links

Browse genome assignments for this superfamily. The SUPERFAMILY hidden Markov model library has been used to carry out SCOP domain assignments to all genomes at the superfamily level.


Alignments of sequences to 1 models in this superfamily are available by clicking on the 'Alignments' icon above. PDB sequences less than 40% identical are shown by default, but any other sequence(s) may be aligned. Select PDB sequences, genome sequences, or paste in or upload your own sequences.


Browse and view proteins in genomes which have different domain combinations including a Coiled-coil domain of nucleotide exchange factor GrpE domain.


Examine the distribution of domain superfamilies, or families, across the major taxonomic kingdoms or genomes within a kingdom. This gives an immediate impression of how superfamilies, or families, are restricted to certain kingdoms of life.


Explore domain occurrence network where nodes represent genomes and edges are domain architectures (shared between genomes) containing the superfamily of interest.

There are 1 hidden Markov models representing the Coiled-coil domain of nucleotide exchange factor GrpE superfamily. Information on how the models are built, and plots showing hydrophobicity, match emmission probabilities and insertion/deletion probabilities can be inspected.


Jump to [ Top of page · SCOP classification · Functional annotation · Gene Ontology (high-coverage) · UniProtKB KeyWords (KW) · Internal database links ]