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Glycerol-3-phosphate (1)-acyltransferase superfamily

SCOP classification
Root:   SCOP hierarchy in SUPERFAMILY [ 0] (11)
Class:   Alpha and beta proteins (a/b) [ 51349] (147)
Fold:   Glycerol-3-phosphate (1)-acyltransferase [ 69592]
Superfamily:   Glycerol-3-phosphate (1)-acyltransferase [ 69593]
Families:   Glycerol-3-phosphate (1)-acyltransferase [ 69594]


Superfamily statistics
Genomes (3,028) Uniprot 2017_06 genome PDB chains (SCOP 1.75)
Domains 15,325 74,366 2
Proteins 15,124 73,669 2


Functional annotation
General category Metabolism
Detailed category Transferases

Document:
Function annotation of SCOP domain superfamilies

Gene Ontology (high-quality)

(show details)
GO termFDR (singleton)FDR (all)SDFO levelAnnotation (direct or inherited)
Biological Process (BP)biosynthetic process0.0000073510Least InformativeDirect
Biological Process (BP)primary metabolic process0.00010350.0003087Least InformativeDirect
Biological Process (BP)single-organism metabolic process0.00000031920Least InformativeDirect
Biological Process (BP)single-organism cellular process0.004440.0000003963Least InformativeInherited
Biological Process (BP)lipid metabolic process00Moderately InformativeDirect
Biological Process (BP)organophosphate biosynthetic process0.00000000001490Moderately InformativeDirect
Biological Process (BP)phospholipid metabolic process00InformativeDirect
Biological Process (BP)glycerolipid metabolic process0.00000000000020410.00000000003144InformativeDirect
Molecular Function (MF)transferase activity00Least InformativeDirect
Molecular Function (MF)transferase activity, transferring acyl groups00InformativeDirect
Molecular Function (MF)O-acyltransferase activity00Highly InformativeDirect
Cellular Component (CC)membrane0.00000018140.0000000003359Least InformativeDirect
Cellular Component (CC)cytoplasmic part0.000012990Least InformativeDirect
Cellular Component (CC)intracellular membrane-bounded organelle0.0038660.000004023Least InformativeInherited
Cellular Component (CC)intracellular organelle part10.5109Least InformativeInherited
Cellular Component (CC)endomembrane system0.0000000000099940Moderately InformativeDirect
Cellular Component (CC)endoplasmic reticulum membrane0.0000008780.00000000000005523InformativeDirect

Document: GO annotation of SCOP domains

Gene Ontology (high-coverage)

(show details)
GO term FDR (all) SDFO level Annotation (direct or inherited)
Biological Process (BP) biosynthetic process 0 Least Informative Direct
Biological Process (BP) primary metabolic process 0.0003087 Least Informative Direct
Biological Process (BP) single-organism metabolic process 0 Least Informative Direct
Biological Process (BP) single-organism cellular process 0.0000003963 Least Informative Direct
Biological Process (BP) cellular component organization or biogenesis 1 Least Informative Inherited
Biological Process (BP) organonitrogen compound metabolic process 1 Least Informative Inherited
Biological Process (BP) cellular aromatic compound metabolic process 1 Least Informative Inherited
Biological Process (BP) cellular nitrogen compound metabolic process 1 Least Informative Inherited
Biological Process (BP) macromolecule metabolic process 1 Least Informative Inherited
Biological Process (BP) heterocycle metabolic process 1 Least Informative Inherited
Biological Process (BP) organic cyclic compound metabolic process 1 Least Informative Inherited
Biological Process (BP) lipid metabolic process 0 Moderately Informative Direct
Biological Process (BP) organophosphate biosynthetic process 0 Moderately Informative Direct
Biological Process (BP) RNA metabolic process 0.7909 Moderately Informative Inherited
Biological Process (BP) phospholipid metabolic process 0 Informative Direct
Biological Process (BP) glycerolipid metabolic process 0.00000000003144 Informative Direct
Biological Process (BP) ammonium ion metabolic process 0.0000003023 Informative Direct
Biological Process (BP) acylglycerol metabolic process 0.02389 Highly Informative Inherited
Biological Process (BP) glycerophospholipid biosynthetic process 0.2564 Highly Informative Inherited
Molecular Function (MF) transferase activity 0 Least Informative Direct
Molecular Function (MF) transferase activity, transferring acyl groups 0 Informative Direct
Molecular Function (MF) O-acyltransferase activity 0 Highly Informative Direct
Molecular Function (MF) acetyltransferase activity 1 Highly Informative Inherited
Cellular Component (CC) membrane 0.0000000003359 Least Informative Direct
Cellular Component (CC) intracellular membrane-bounded organelle 0.000004023 Least Informative Direct
Cellular Component (CC) cytoplasmic part 0 Least Informative Direct
Cellular Component (CC) intracellular organelle part 0.5109 Least Informative Inherited
Cellular Component (CC) non-membrane-bounded organelle 1 Least Informative Inherited
Cellular Component (CC) mitochondrial envelope 0.0006004 Moderately Informative Direct
Cellular Component (CC) endomembrane system 0 Moderately Informative Direct
Cellular Component (CC) bounding membrane of organelle 0.01387 Moderately Informative Inherited
Cellular Component (CC) whole membrane 0.07725 Moderately Informative Inherited
Cellular Component (CC) endoplasmic reticulum membrane 0.00000000000005523 Informative Direct
Cellular Component (CC) outer membrane 0.0007555 Informative Direct
Cellular Component (CC) microbody 0.00004364 Informative Direct
Cellular Component (CC) mitochondrial outer membrane 0.00006099 Highly Informative Direct
Cellular Component (CC) lipid droplet 0.00000002565 Highly Informative Direct
Cellular Component (CC) microbody membrane 0.00002037 Highly Informative Direct

Document: GO annotation of SCOP domains

Enzyme Commission (EC)

(show details)
EC termFDR (all)SDEO levelAnnotation (direct or inherited)
Enzyme Commission (EC)Ligases0.2006Least InformativeInherited
Enzyme Commission (EC)Transferring groups other than amino-acyl groups0Moderately InformativeDirect

Document: EC annotation of SCOP domains

UniProtKB KeyWords (KW)

(show details)
KW termFDR (all)SDKW levelAnnotation (direct or inherited)
Biological processLipid metabolism0Moderately InformativeDirect
Biological processLipid biosynthesis0InformativeDirect
Biological processPhospholipid metabolism0Highly InformativeDirect
Cellular componentMembrane0Least InformativeDirect
Cellular componentEndoplasmic reticulum0Moderately InformativeDirect
Cellular componentCell membrane0.1597Moderately InformativeInherited
Cellular componentMitochondrion0.7479Moderately InformativeInherited
Cellular componentCell inner membrane0InformativeDirect
Cellular componentMitochondrion outer membrane0.000000005034InformativeDirect
Cellular componentLipid droplet0Highly InformativeDirect
DomainTransmembrane0Least InformativeDirect
Post-translational modificationTransferase0Least InformativeDirect
Post-translational modificationAcyltransferase0InformativeDirect

Document: KW annotation of SCOP domains

Jump to [ Top of page · SCOP classification · Functional annotation · Gene Ontology (high-quality) · Gene Ontology (high-coverage) · Enzyme Commission (EC) · UniProtKB KeyWords (KW) ]

Internal database links

Browse genome assignments for this superfamily. The SUPERFAMILY hidden Markov model library has been used to carry out SCOP domain assignments to all genomes at the superfamily level.


Alignments of sequences to 1 models in this superfamily are available by clicking on the 'Alignments' icon above. PDB sequences less than 40% identical are shown by default, but any other sequence(s) may be aligned. Select PDB sequences, genome sequences, or paste in or upload your own sequences.


Browse and view proteins in genomes which have different domain combinations including a Glycerol-3-phosphate (1)-acyltransferase domain.


Examine the distribution of domain superfamilies, or families, across the major taxonomic kingdoms or genomes within a kingdom. This gives an immediate impression of how superfamilies, or families, are restricted to certain kingdoms of life.


Explore domain occurrence network where nodes represent genomes and edges are domain architectures (shared between genomes) containing the superfamily of interest.

There are 1 hidden Markov models representing the Glycerol-3-phosphate (1)-acyltransferase superfamily. Information on how the models are built, and plots showing hydrophobicity, match emmission probabilities and insertion/deletion probabilities can be inspected.


Jump to [ Top of page · SCOP classification · Functional annotation · Gene Ontology (high-quality) · Gene Ontology (high-coverage) · Enzyme Commission (EC) · UniProtKB KeyWords (KW) · Internal database links ]