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Clathrin adaptor core protein family

SCOP classification
Root:   SCOP hierarchy in SUPERFAMILY [ 0] (11)
Class:   All alpha proteins [ 46456] (284)
Fold:   alpha-alpha superhelix [ 48370] (24)
Superfamily:   ARM repeat [ 48371] (23)
Family:   Clathrin adaptor core protein [ 74771] (2)


Family statistics
Genomes (506) Uniprot 2017_06 genome PDB chains (SCOP 1.75)
Domains 3,809 9,580 5
Proteins 3,794 9,565 5


Gene Ontology (high-coverage)

(
show details)
GO term FDR (all) SDFO level Annotation (direct or inherited)
Biological Process (BP) single-organism metabolic process 1 Least Informative Inherited
Biological Process (BP) biological regulation 1 Least Informative Inherited
Biological Process (BP) single-organism cellular process 0.9431 Least Informative Inherited
Biological Process (BP) transport 0 Moderately Informative Direct
Biological Process (BP) single-organism localization 0.00000002534 Moderately Informative Direct
Biological Process (BP) system development 1 Moderately Informative Inherited
Biological Process (BP) multi-organism process 0.6547 Moderately Informative Inherited
Biological Process (BP) regulation of localization 0.102 Moderately Informative Inherited
Biological Process (BP) regulation of biological quality 0.6907 Moderately Informative Inherited
Biological Process (BP) macromolecule localization 0.06703 Moderately Informative Inherited
Biological Process (BP) organelle organization 0.1588 Moderately Informative Inherited
Biological Process (BP) protein transport 0 Informative Direct
Biological Process (BP) vesicle-mediated transport 0 Informative Direct
Biological Process (BP) intracellular transport 0.0000000001264 Informative Direct
Biological Process (BP) pigment metabolic process 0.0001022 Informative Direct
Biological Process (BP) single-organism cellular localization 0.02497 Informative Inherited
Biological Process (BP) interspecies interaction between organisms 0.01671 Informative Inherited
Biological Process (BP) secretion 0.5455 Informative Inherited
Biological Process (BP) movement of cell or subcellular component 0.001637 Informative Inherited
Biological Process (BP) vesicle organization 0.000000000006162 Highly Informative Direct
Biological Process (BP) microtubule-based process 0.0000000004611 Highly Informative Direct
Biological Process (BP) vacuole organization 0.000000001046 Highly Informative Direct
Biological Process (BP) establishment of organelle localization 0.001019 Highly Informative Inherited
Biological Process (BP) single-organism intracellular transport 0.02602 Highly Informative Inherited
Biological Process (BP) symbiosis, encompassing mutualism through parasitism 0.1884 Highly Informative Inherited
Biological Process (BP) Golgi vesicle transport 0.01072 Highly Informative Inherited
Molecular Function (MF) binding 0.656 Least Informative Inherited
Molecular Function (MF) transporter activity 0.000000884 Moderately Informative Direct
Molecular Function (MF) protein binding 0.01638 Moderately Informative Inherited
Molecular Function (MF) enzyme binding 0.031 Informative Inherited
Molecular Function (MF) peptide transporter activity 0 Highly Informative Direct
Cellular Component (CC) membrane 0 Least Informative Direct
Cellular Component (CC) cytoplasmic part 0 Least Informative Direct
Cellular Component (CC) macromolecular complex 0.0000000000001402 Least Informative Direct
Cellular Component (CC) intracellular organelle part 0.00000003075 Least Informative Direct
Cellular Component (CC) intracellular membrane-bounded organelle 0.2659 Least Informative Inherited
Cellular Component (CC) endomembrane system 0 Moderately Informative Direct
Cellular Component (CC) organelle membrane 0 Moderately Informative Direct
Cellular Component (CC) membrane protein complex 0 Moderately Informative Direct
Cellular Component (CC) vesicle 0 Moderately Informative Direct
Cellular Component (CC) cell periphery 0.3916 Moderately Informative Inherited
Cellular Component (CC) whole membrane 0 Informative Direct
Cellular Component (CC) bounding membrane of organelle 0 Informative Direct
Cellular Component (CC) Golgi apparatus 0 Informative Direct
Cellular Component (CC) cytoplasmic vesicle part 0 Informative Direct
Cellular Component (CC) organelle subcompartment 0.0000000000001684 Informative Direct
Cellular Component (CC) vacuolar part 0.00002046 Informative Direct
Cellular Component (CC) plasma membrane part 0.03253 Informative Inherited
Cellular Component (CC) lytic vacuole 0.006483 Informative Inherited
Cellular Component (CC) membrane coat 0 Highly Informative Direct
Cellular Component (CC) coated vesicle 0 Highly Informative Direct
Cellular Component (CC) Golgi-associated vesicle membrane 0.0000000000001179 Highly Informative Direct
Cellular Component (CC) cytoplasmic vesicle membrane 0.00000000417 Highly Informative Direct
Cellular Component (CC) transport vesicle 0.000000006599 Highly Informative Direct
Cellular Component (CC) plasma membrane protein complex 0.0006776 Highly Informative Direct
Cellular Component (CC) vacuolar membrane 0.7324 Highly Informative Inherited
Cellular Component (CC) Golgi subcompartment 0.03196 Highly Informative Inherited

Document: GO annotation of SCOP domains

UniProtKB KeyWords (KW)

(show details)
KW termFDR (all)SDKW levelAnnotation (direct or inherited)
Biological processTransport0Least InformativeDirect
Biological processProtein transport0Moderately InformativeDirect
Biological processEndocytosis0InformativeDirect
Biological processER-Golgi transport0Highly InformativeDirect
Cellular componentMembrane0Least InformativeDirect
Cellular componentGolgi apparatus0Moderately InformativeDirect
Cellular componentCytoplasmic vesicle0InformativeDirect
Cellular componentEndosome0.0004205InformativeDirect
Cellular componentCoated pit0Highly InformativeDirect
DomainRepeat0Least InformativeDirect
Molecular functionLipid-binding0.0000001358InformativeDirect
Post-translational modificationPhosphoprotein0.000007097Least InformativeDirect
Post-translational modificationAcetylation0.0001336Least InformativeDirect

Document: KW annotation of SCOP domains

Jump to [ Top of page · SCOP classification · Gene Ontology (high-coverage) · UniProtKB KeyWords (KW) ]

Internal database links

   
Superfamily level     Family level

Browse genome assignments for this superfamily. The SUPERFAMILY hidden Markov model library has been used to carry out SCOP domain assignments to all genomes at the superfamily level.


   
Superfamily level     Family level

Alignments of sequences to 44 models in this superfamily are available by clicking on the 'Alignments' icon above. PDB sequences less than 40% identical are shown by default, but any other sequence(s) may be aligned. Select PDB sequences, genome sequences, or paste in or upload your own sequences.


Superfamily level

Browse and view proteins in genomes which have different domain combinations including a ARM repeat domain.


   
Superfamily level     Family level

Examine the distribution of domain superfamilies, or families, across the major taxonomic kingdoms or genomes within a kingdom. This gives an immediate impression of how superfamilies, or families, are restricted to certain kingdoms of life.


Jump to [ Top of page · SCOP classification · Gene Ontology (high-coverage) · UniProtKB KeyWords (KW) · Internal database links ]