SUPERFAMILY 1.75 HMM library and genome assignments server

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Ephrin ectodomain family

SCOP classification
Root:   SCOP hierarchy in SUPERFAMILY [ 0] (11)
Class:   All beta proteins [ 48724] (174)
Fold:   Cupredoxin-like [ 49502] (2)
Superfamily:   Cupredoxins [ 49503] (7)
Family:   Ephrin ectodomain [ 74874] (2)


Family statistics
Genomes (66) Uniprot 2018_03 genome PDB chains (SCOP 1.75)
Domains 589 1,333 4
Proteins 589 1,330 4


Disease Ontology (DO)

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show details)
DO termFDR (all)SDDO levelAnnotation (direct or inherited)
Disease Ontology (DO)organ system cancer0.01337Least InformativeInherited
Disease Ontology (DO)osteosarcoma0.0003099InformativeDirect

Document: DO annotation of SCOP domains

Mouse Phenotype (MP)

(show details)
MP termFDR (all)SDMP levelAnnotation (direct or inherited)
Mammalian Phenotype (MP)nervous system phenotype0.006411Least InformativeInherited
Mammalian Phenotype (MP)growth/size/body region phenotype0.2564Least InformativeInherited
Mammalian Phenotype (MP)abnormal neuron morphology0.0001039Moderately InformativeDirect
Mammalian Phenotype (MP)abnormal craniofacial morphology0.02641Moderately InformativeInherited
Mammalian Phenotype (MP)abnormal digestive system morphology0.02685Moderately InformativeInherited
Mammalian Phenotype (MP)abnormal synaptic transmission0.03935Moderately InformativeInherited
Mammalian Phenotype (MP)abnormal brain morphology0.1453Moderately InformativeInherited
Mammalian Phenotype (MP)abnormal CNS synaptic transmission0.0006301InformativeDirect
Mammalian Phenotype (MP)abnormal mouth morphology0.003199InformativeInherited
Mammalian Phenotype (MP)abnormal neurite morphology0.1347InformativeInherited
Mammalian Phenotype (MP)abnormal olfactory bulb morphology0.00009511Highly InformativeDirect
Mammalian Phenotype (MP)abnormal axon morphology0.0002117Highly InformativeDirect
Mammalian Phenotype (MP)cleft palate0.0004246Highly InformativeDirect
Mammalian Phenotype (MP)abnormal diencephalon morphology0.02676Highly InformativeInherited
Mammalian Phenotype (MP)abnormal long term potentiation0.05801Highly InformativeInherited

Document: MP annotation of SCOP domains

Worm Phenotype (WP)

(show details)
WP termFDR (all)SDWP levelAnnotation (direct or inherited)
Worm Phenotype (WP)cell physiology variant0.01324Least InformativeInherited
Worm Phenotype (WP)cell death variant0.0001859Moderately InformativeDirect

Document: WP annotation of SCOP domains

Zebrafish Anatomy (ZA)

(show details)
ZA termFDR (all)SDZA levelAnnotation (direct or inherited)
Zebrafish Anatomy (ZA)compound organ0Least InformativeDirect

Document: ZA annotation of SCOP domains

Xenopus Anatomy (XA)

(show details)
XA termFDR (all)SDXA levelAnnotation (direct or inherited)
Xenopus ANatomical entity (XAN)head0Least InformativeDirect
Xenopus ANatomical entity (XAN)nervous system0.6204Least InformativeInherited
Xenopus ANatomical entity (XAN)cavitated compound organ0.6483Least InformativeInherited
Xenopus ANatomical entity (XAN)multi-tissue structure0.01514Moderately InformativeInherited
Xenopus ANatomical entity (XAN)sensory system0.08887Moderately InformativeInherited
Xenopus ANatomical entity (XAN)eye0.07877InformativeInherited

Document: XA annotation of SCOP domains

Jump to [ Top of page · SCOP classification · Disease Ontology (DO) · Mouse Phenotype (MP) · Worm Phenotype (WP) · Zebrafish Anatomy (ZA) · Xenopus Anatomy (XA) ]

Internal database links

   
Superfamily level     Family level

Browse genome assignments for this superfamily. The SUPERFAMILY hidden Markov model library has been used to carry out SCOP domain assignments to all genomes at the superfamily level.


   
Superfamily level     Family level

Alignments of sequences to 144 models in this superfamily are available by clicking on the 'Alignments' icon above. PDB sequences less than 40% identical are shown by default, but any other sequence(s) may be aligned. Select PDB sequences, genome sequences, or paste in or upload your own sequences.


Superfamily level

Browse and view proteins in genomes which have different domain combinations including a Cupredoxins domain.


   
Superfamily level     Family level

Examine the distribution of domain superfamilies, or families, across the major taxonomic kingdoms or genomes within a kingdom. This gives an immediate impression of how superfamilies, or families, are restricted to certain kingdoms of life.


Jump to [ Top of page · SCOP classification · Disease Ontology (DO) · Mouse Phenotype (MP) · Worm Phenotype (WP) · Zebrafish Anatomy (ZA) · Xenopus Anatomy (XA) · Internal database links ]