SUPERFAMILY 1.75 HMM library and genome assignments server

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Clathrin coat assembly domain family

SCOP classification
Root:   SCOP hierarchy in SUPERFAMILY [ 0] (11)
Class:   Alpha and beta proteins (a+b) [ 53931] (376)
Fold:   Profilin-like [ 55769] (10)
Superfamily:   SNARE-like [ 64356] (4)
Family:   Clathrin coat assembly domain [ 75521] (2)


Family statistics
Genomes (503) Uniprot 2018_03 genome PDB chains (SCOP 1.75)
Domains 2,734 7,612 5
Proteins 2,731 7,609 5


Human Phenotype (HP)

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show details)
HP termFDR (all)SDHP levelAnnotation (direct or inherited)
Phenotypic Abnormality (PA)Abnormality of nervous system physiology0.2166Least InformativeInherited
Phenotypic Abnormality (PA)Abnormality of the face0.2915Least InformativeInherited
Phenotypic Abnormality (PA)Abnormality of higher mental function0.3095Moderately InformativeInherited
Phenotypic Abnormality (PA)Abnormal oral cavity morphology1Moderately InformativeInherited
Phenotypic Abnormality (PA)Abnormal lip morphology0.05093InformativeInherited
Phenotypic Abnormality (PA)Abnormal facial shape0.05903InformativeInherited
Phenotypic Abnormality (PA)Neurological speech impairment0.1004InformativeInherited
Phenotypic Abnormality (PA)Wide mouth0.0001991Highly InformativeDirect
Phenotypic Abnormality (PA)Coarse facial features0.0007758Highly InformativeDirect
Phenotypic Abnormality (PA)Abnormality of the philtrum0.01182Highly InformativeInherited

Document: HP annotation of SCOP domains

Worm Phenotype (WP)

(show details)
WP termFDR (all)SDWP levelAnnotation (direct or inherited)
Worm Phenotype (WP)organism metabolism processing variant0Least InformativeDirect
Worm Phenotype (WP)larval lethal0Least InformativeDirect
Worm Phenotype (WP)larval arrest0Least InformativeDirect
Worm Phenotype (WP)cell physiology variant0Least InformativeDirect
Worm Phenotype (WP)cell development variant0.002545Least InformativeInherited
Worm Phenotype (WP)organism behavior variant0.009493Least InformativeInherited
Worm Phenotype (WP)organism environmental stimulus response variant0.2308Least InformativeInherited
Worm Phenotype (WP)pattern of transgene expression variant0Moderately InformativeDirect
Worm Phenotype (WP)cell type morphology variant0.00001302Moderately InformativeDirect
Worm Phenotype (WP)organism segment morphology variant0.0001148Moderately InformativeDirect
Worm Phenotype (WP)body region morphology variant0.000117Moderately InformativeDirect
Worm Phenotype (WP)movement variant0.0007301Moderately InformativeDirect
Worm Phenotype (WP)organ system development variant0.0032Moderately InformativeInherited
Worm Phenotype (WP)chemical response variant0.02925Moderately InformativeInherited
Worm Phenotype (WP)protein expression variant0.156Moderately InformativeInherited
Worm Phenotype (WP)vesicle organization variant0.0001098InformativeDirect
Worm Phenotype (WP)acetylcholinesterase inhibitor response variant0.0001134InformativeDirect
Worm Phenotype (WP)pattern protein expression variant0.0002657InformativeDirect
Worm Phenotype (WP)drug resistant0.0003581InformativeDirect
Worm Phenotype (WP)sensillum morphology variant0.0003706InformativeDirect
Worm Phenotype (WP)chemical resistant0.0009332InformativeDirect
Worm Phenotype (WP)dumpy0.00000437Highly InformativeDirect
Worm Phenotype (WP)intestinal development variant0.00003635Highly InformativeDirect

Document: WP annotation of SCOP domains

Yeast Phenotype (YP)

(show details)
YP termFDR (all)SDYP levelAnnotation (direct or inherited)
Yeast Phenotype (YP)resistance to chemicals0Least InformativeDirect
Yeast Phenotype (YP)intracellular transport0.02104InformativeInherited

Document: YP annotation of SCOP domains

Fly Phenotype (FP)

(show details) Document: FP annotation of SCOP domains

Fly Anatomy (FA)

(show details)
FA termFDR (all)SDFA levelAnnotation (direct or inherited)
Fly Anatomy (FA)larva0Least InformativeDirect

Document: FA annotation of SCOP domains

Zebrafish Anatomy (ZA)

(show details)
ZA termFDR (all)SDZA levelAnnotation (direct or inherited)
Zebrafish Anatomy (ZA)organism subdivision0Least InformativeDirect

Document: ZA annotation of SCOP domains

Xenopus Anatomy (XA)

(show details) Document: XA annotation of SCOP domains

Arabidopsis Plant Ontology (AP)

(show details)
AP termFDR (all)SDAP levelAnnotation (direct or inherited)
Plant structure DEvelopment stage (PDE)4 leaf senescence stage0Least InformativeDirect
Plant structure DEvelopment stage (PDE)E expanded cotyledon stage0Least InformativeDirect
Plant structure DEvelopment stage (PDE)C globular stage0Least InformativeDirect
Plant structure DEvelopment stage (PDE)D bilateral stage0Least InformativeDirect
Plant structure DEvelopment stage (PDE)LP.12 twelve leaves visible stage0Least InformativeDirect
Plant structure DEvelopment stage (PDE)LP.08 eight leaves visible stage0Least InformativeDirect
Plant structure DEvelopment stage (PDE)LP.02 two leaves visible stage0Least InformativeDirect
Plant structure DEvelopment stage (PDE)LP.10 ten leaves visible stage0Least InformativeDirect
Plant structure DEvelopment stage (PDE)LP.04 four leaves visible stage0Least InformativeDirect
Plant structure DEvelopment stage (PDE)LP.06 six leaves visible stage0Least InformativeDirect

Document: AP annotation of SCOP domains

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Internal database links

   
Superfamily level     Family level

Browse genome assignments for this superfamily. The SUPERFAMILY hidden Markov model library has been used to carry out SCOP domain assignments to all genomes at the superfamily level.


   
Superfamily level     Family level

Alignments of sequences to 8 models in this superfamily are available by clicking on the 'Alignments' icon above. PDB sequences less than 40% identical are shown by default, but any other sequence(s) may be aligned. Select PDB sequences, genome sequences, or paste in or upload your own sequences.


Superfamily level

Browse and view proteins in genomes which have different domain combinations including a SNARE-like domain.


   
Superfamily level     Family level

Examine the distribution of domain superfamilies, or families, across the major taxonomic kingdoms or genomes within a kingdom. This gives an immediate impression of how superfamilies, or families, are restricted to certain kingdoms of life.


Jump to [ Top of page · SCOP classification · Human Phenotype (HP) · Worm Phenotype (WP) · Yeast Phenotype (YP) · Fly Phenotype (FP) · Fly Anatomy (FA) · Zebrafish Anatomy (ZA) · Xenopus Anatomy (XA) · Arabidopsis Plant Ontology (AP) · Internal database links ]