SUPERFAMILY 1.75 HMM library and genome assignments server

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Release factor family

SCOP classification
Root:   SCOP hierarchy in SUPERFAMILY [ 0] (11)
Class:   Multi-domain proteins (alpha and beta) [ 56572] (66)
Fold:   Release factor [ 75619]
Superfamily:   Release factor [ 75620]
Family:   Release factor [ 75621] (2)


Family statistics
Genomes (3,071) Uniprot 2017_06 genome PDB chains (SCOP 1.75)
Domains 6,027 33,772 5
Proteins 6,025 33,771 5


Gene Ontology (high-quality)

(
show details)
GO termFDR (singleton)FDR (all)SDFO levelAnnotation (direct or inherited)
Biological Process (BP)cellular nitrogen compound metabolic process0.00022550.0000003331Least InformativeDirect
Biological Process (BP)biosynthetic process0.00026020.0000004301Least InformativeDirect
Biological Process (BP)single-organism cellular process0.2640.1459Least InformativeInherited
Biological Process (BP)organonitrogen compound metabolic process0.0036550.00003827Least InformativeInherited
Biological Process (BP)primary metabolic process0.031530.003121Least InformativeInherited
Biological Process (BP)macromolecule metabolic process0.00049650.001851Least InformativeInherited
Biological Process (BP)cellular amide metabolic process0.00000000055140.000000000453Moderately InformativeDirect
Biological Process (BP)cellular macromolecule biosynthetic process0.0000000022230.000000000006347Moderately InformativeDirect
Biological Process (BP)gene expression0.000000010860.00000000003589Moderately InformativeDirect
Biological Process (BP)cellular nitrogen compound biosynthetic process0.00000039320.0000001871Moderately InformativeDirect
Biological Process (BP)macromolecular complex subunit organization0.0000013420.00000003833Moderately InformativeDirect
Biological Process (BP)cellular protein metabolic process0.0000023810.0000001726Moderately InformativeDirect
Biological Process (BP)translation0.00000000000054780InformativeDirect
Biological Process (BP)cellular component disassembly0.00000000000062610Highly InformativeDirect
Molecular Function (MF)binding0.21780.2027Least InformativeInherited
Molecular Function (MF)heterocyclic compound binding0.00006690.000005619Moderately InformativeDirect
Molecular Function (MF)organic cyclic compound binding0.000097180.000007231Moderately InformativeDirect
Molecular Function (MF)RNA binding0.00000000320.000000000001217InformativeDirect
Molecular Function (MF)translation factor activity, RNA binding0.0000000000000022550.000000000001766Highly InformativeDirect

Document: GO annotation of SCOP domains

Gene Ontology (high-coverage)

(show details)
GO term FDR (all) SDFO level Annotation (direct or inherited)
Biological Process (BP) cellular nitrogen compound metabolic process 0.0000003331 Least Informative Direct
Biological Process (BP) biosynthetic process 0.0000004301 Least Informative Direct
Biological Process (BP) organonitrogen compound metabolic process 0.00003827 Least Informative Direct
Biological Process (BP) single-organism cellular process 0.1459 Least Informative Inherited
Biological Process (BP) primary metabolic process 0.003121 Least Informative Inherited
Biological Process (BP) macromolecule metabolic process 0.001851 Least Informative Inherited
Biological Process (BP) cellular amide metabolic process 0.000000000453 Moderately Informative Direct
Biological Process (BP) cellular macromolecule biosynthetic process 0.000000000006347 Moderately Informative Direct
Biological Process (BP) gene expression 0.00000000003589 Moderately Informative Direct
Biological Process (BP) cellular nitrogen compound biosynthetic process 0.0000001871 Moderately Informative Direct
Biological Process (BP) macromolecular complex subunit organization 0.00000003833 Moderately Informative Direct
Biological Process (BP) cellular protein metabolic process 0.0000001726 Moderately Informative Direct
Biological Process (BP) translation 0 Informative Direct
Biological Process (BP) cellular component disassembly 0 Highly Informative Direct
Molecular Function (MF) binding 0.2027 Least Informative Inherited
Molecular Function (MF) heterocyclic compound binding 0.000005619 Moderately Informative Direct
Molecular Function (MF) organic cyclic compound binding 0.000007231 Moderately Informative Direct
Molecular Function (MF) RNA binding 0.000000000001217 Informative Direct
Molecular Function (MF) translation factor activity, RNA binding 0.000000000001766 Highly Informative Direct
Cellular Component (CC) cytoplasmic part 0.0000001626 Least Informative Direct
Cellular Component (CC) intracellular membrane-bounded organelle 0.00007091 Least Informative Direct
Cellular Component (CC) plastid 0.00001021 Informative Direct

Document: GO annotation of SCOP domains

UniProtKB KeyWords (KW)

(show details)
KW termFDR (all)SDKW levelAnnotation (direct or inherited)
Biological processProtein biosynthesis0InformativeDirect
Cellular componentCytoplasm0Least InformativeDirect
Coding sequence diversityRibosomal frameshifting0Moderately InformativeDirect
Post-translational modificationMethylation0Moderately InformativeDirect

Document: KW annotation of SCOP domains

Jump to [ Top of page · SCOP classification · Gene Ontology (high-quality) · Gene Ontology (high-coverage) · UniProtKB KeyWords (KW) ]

Internal database links

   
Superfamily level     Family level

Browse genome assignments for this superfamily. The SUPERFAMILY hidden Markov model library has been used to carry out SCOP domain assignments to all genomes at the superfamily level.


   
Superfamily level     Family level

Alignments of sequences to 3 models in this superfamily are available by clicking on the 'Alignments' icon above. PDB sequences less than 40% identical are shown by default, but any other sequence(s) may be aligned. Select PDB sequences, genome sequences, or paste in or upload your own sequences.


Superfamily level

Browse and view proteins in genomes which have different domain combinations including a Release factor domain.


   
Superfamily level     Family level

Examine the distribution of domain superfamilies, or families, across the major taxonomic kingdoms or genomes within a kingdom. This gives an immediate impression of how superfamilies, or families, are restricted to certain kingdoms of life.


Jump to [ Top of page · SCOP classification · Gene Ontology (high-quality) · Gene Ontology (high-coverage) · UniProtKB KeyWords (KW) · Internal database links ]