SUPERFAMILY 1.75 HMM library and genome assignments server

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Cullin homology domain family

SCOP classification
Root:   SCOP hierarchy in SUPERFAMILY [ 0] (11)
Class:   Multi-domain proteins (alpha and beta) [ 56572] (66)
Fold:   Cullin homology domain [ 75631]
Superfamily:   Cullin homology domain [ 75632]
Family:   Cullin homology domain [ 75633] (2)


Family statistics
Genomes (484) Uniprot 2018_03 genome PDB chains (SCOP 1.75)
Domains 2,505 6,851 4
Proteins 2,495 6,827 4


Mouse Phenotype (MP)

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show details)
MP termFDR (all)SDMP levelAnnotation (direct or inherited)
Mammalian Phenotype (MP)cellular phenotype0Least InformativeDirect
Mammalian Phenotype (MP)mortality/aging0Least InformativeDirect
Mammalian Phenotype (MP)growth/size/body region phenotype0.01638Least InformativeInherited
Mammalian Phenotype (MP)abnormal embryo morphology0.008449Moderately InformativeInherited
Mammalian Phenotype (MP)prenatal lethality0.1644Moderately InformativeInherited
Mammalian Phenotype (MP)abnormal prenatal body size0.001469InformativeInherited
Mammalian Phenotype (MP)abnormal embryonic growth/weight/body size0.002368InformativeInherited
Mammalian Phenotype (MP)embryonic lethality prior to organogenesis0.006525InformativeInherited
Mammalian Phenotype (MP)embryonic lethality between implantation and somite formation, complete penetrance0.0004058Highly InformativeDirect

Document: MP annotation of SCOP domains

Worm Phenotype (WP)

(show details)
WP termFDR (all)SDWP levelAnnotation (direct or inherited)
Worm Phenotype (WP)organism metabolism processing variant0Least InformativeDirect
Worm Phenotype (WP)cell physiology variant0Least InformativeDirect
Worm Phenotype (WP)organism environmental stimulus response variant0.0002552Least InformativeDirect
Worm Phenotype (WP)cell development variant0.002372Least InformativeInherited
Worm Phenotype (WP)chemical response variant0.000001098Moderately InformativeDirect
Worm Phenotype (WP)protein expression variant0.0003761Moderately InformativeDirect
Worm Phenotype (WP)protein protein interaction variant0.0006896Moderately InformativeDirect
Worm Phenotype (WP)cell death variant0.0009363Moderately InformativeDirect
Worm Phenotype (WP)organ system development variant0.003035Moderately InformativeInherited
Worm Phenotype (WP)gametogenesis variant0.2993Moderately InformativeInherited
Worm Phenotype (WP)accumulated germline cell corpses0.0000000001262InformativeDirect
Worm Phenotype (WP)pattern protein expression variant0.0000000007053InformativeDirect
Worm Phenotype (WP)chemical hypersensitive0.0000000000004355Highly InformativeDirect
Worm Phenotype (WP)apoptosis increased0.000000000002097Highly InformativeDirect
Worm Phenotype (WP)spontaneous mutation rate increased0.0000005036Highly InformativeDirect

Document: WP annotation of SCOP domains

Yeast Phenotype (YP)

(show details) Document: YP annotation of SCOP domains

Fly Anatomy (FA)

(show details)
FA termFDR (all)SDFA levelAnnotation (direct or inherited)
Fly Anatomy (FA)multi-tissue structure0Least InformativeDirect
Fly Anatomy (FA)somatic cell0Least InformativeDirect
Fly Anatomy (FA)gonad0Moderately InformativeDirect
Fly Anatomy (FA)female organism0.0009412Moderately InformativeDirect
Fly Anatomy (FA)epithelium0.1355Moderately InformativeInherited
Fly Anatomy (FA)epithelial cell0.00453InformativeInherited
Fly Anatomy (FA)egg chamber0.5849InformativeInherited
Fly Anatomy (FA)follicle cell0.0003393Highly InformativeDirect

Document: FA annotation of SCOP domains

Xenopus Anatomy (XA)

(show details)
XA termFDR (all)SDXA levelAnnotation (direct or inherited)
Xenopus ANatomical entity (XAN)genital system0Least InformativeDirect
Xenopus ANatomical entity (XAN)nervous system0Least InformativeDirect
Xenopus ANatomical entity (XAN)head0Least InformativeDirect
Xenopus ANatomical entity (XAN)trunk0Least InformativeDirect
Xenopus ANatomical entity (XAN)anatomical cluster0Least InformativeDirect
Xenopus ANatomical entity (XAN)cavitated compound organ0Least InformativeDirect
Xenopus ANatomical entity (XAN)testis0Moderately InformativeDirect
Xenopus DEvelopment stage (XDE)post-embryonic stage0Least InformativeDirect

Document: XA annotation of SCOP domains

Arabidopsis Plant Ontology (AP)

(show details) Document: AP annotation of SCOP domains

Jump to [ Top of page · SCOP classification · Mouse Phenotype (MP) · Worm Phenotype (WP) · Yeast Phenotype (YP) · Fly Anatomy (FA) · Xenopus Anatomy (XA) · Arabidopsis Plant Ontology (AP) ]

Internal database links

   
Superfamily level     Family level

Browse genome assignments for this superfamily. The SUPERFAMILY hidden Markov model library has been used to carry out SCOP domain assignments to all genomes at the superfamily level.


   
Superfamily level     Family level

Alignments of sequences to 2 models in this superfamily are available by clicking on the 'Alignments' icon above. PDB sequences less than 40% identical are shown by default, but any other sequence(s) may be aligned. Select PDB sequences, genome sequences, or paste in or upload your own sequences.


Superfamily level

Browse and view proteins in genomes which have different domain combinations including a Cullin homology domain domain.


   
Superfamily level     Family level

Examine the distribution of domain superfamilies, or families, across the major taxonomic kingdoms or genomes within a kingdom. This gives an immediate impression of how superfamilies, or families, are restricted to certain kingdoms of life.


Jump to [ Top of page · SCOP classification · Mouse Phenotype (MP) · Worm Phenotype (WP) · Yeast Phenotype (YP) · Fly Anatomy (FA) · Xenopus Anatomy (XA) · Arabidopsis Plant Ontology (AP) · Internal database links ]