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Riboflavin kinase-like superfamily

SCOP classification
Root:   SCOP hierarchy in SUPERFAMILY [ 0] (11)
Class:   All beta proteins [ 48724] (174)
Fold:   Reductase/isomerase/elongation factor common domain [ 50412] (4)
Superfamily:   Riboflavin kinase-like [ 82114] (2)
Families:   ATP-dependent riboflavin kinase-like [ 82115] (2)
  CTP-dependent riboflavin kinase-like [ 159154]


Superfamily statistics
Genomes (3,049) Uniprot 2017_06 genome PDB chains (SCOP 1.75)
Domains 3,303 17,808 7
Proteins 3,277 17,742 7


Functional annotation
General category Metabolism
Detailed category Other enzymes

Document:
Function annotation of SCOP domain superfamilies

Gene Ontology (high-quality)

(show details)
GO termFDR (singleton)FDR (all)SDFO levelAnnotation (direct or inherited)
Biological Process (BP)organic cyclic compound metabolic process0.00014610.00004096Least InformativeDirect
Biological Process (BP)organonitrogen compound metabolic process0.00060730.0004008Least InformativeDirect
Biological Process (BP)single-organism metabolic process0.03180.0001875Least InformativeInherited
Biological Process (BP)cellular nitrogen compound metabolic process0.041860.004902Least InformativeInherited
Biological Process (BP)heterocycle metabolic process0.030110.002797Least InformativeInherited
Biological Process (BP)biosynthetic process0.038560.001467Least InformativeInherited
Biological Process (BP)heterocycle biosynthetic process0.0000035220.00000001825Moderately InformativeDirect
Biological Process (BP)organic cyclic compound biosynthetic process0.0000054070.00000004561Moderately InformativeDirect
Molecular Function (MF)transferase activity0.000120.00000003403Least InformativeDirect
Molecular Function (MF)transferase activity, transferring phosphorus-containing groups0.0000010970.00000000005322Moderately InformativeDirect
Molecular Function (MF)kinase activity0.00000042230.000000000009199InformativeDirect
Molecular Function (MF)phosphotransferase activity, alcohol group as acceptor0.0000001270.000000000003348InformativeDirect

Document: GO annotation of SCOP domains

Gene Ontology (high-coverage)

(show details)
GO term FDR (all) SDFO level Annotation (direct or inherited)
Biological Process (BP) single-organism metabolic process 0.0001875 Least Informative Direct
Biological Process (BP) organic cyclic compound metabolic process 0.00004096 Least Informative Direct
Biological Process (BP) organonitrogen compound metabolic process 0.0004008 Least Informative Direct
Biological Process (BP) cellular nitrogen compound metabolic process 0.004902 Least Informative Inherited
Biological Process (BP) heterocycle metabolic process 0.002797 Least Informative Inherited
Biological Process (BP) biosynthetic process 0.001467 Least Informative Inherited
Biological Process (BP) heterocycle biosynthetic process 0.00000001825 Moderately Informative Direct
Biological Process (BP) organic cyclic compound biosynthetic process 0.00000004561 Moderately Informative Direct
Molecular Function (MF) transferase activity 0.00000003403 Least Informative Direct
Molecular Function (MF) transferase activity, transferring phosphorus-containing groups 0.00000000005322 Moderately Informative Direct
Molecular Function (MF) kinase activity 0.000000000009199 Informative Direct
Molecular Function (MF) phosphotransferase activity, alcohol group as acceptor 0.000000000003348 Informative Direct

Document: GO annotation of SCOP domains

Enzyme Commission (EC)

(show details)
EC termFDR (all)SDEO levelAnnotation (direct or inherited)
Enzyme Commission (EC)Nucleotidyltransferases1Least InformativeInherited
Enzyme Commission (EC)Phosphotransferases with an alcohol group as accep0Moderately InformativeDirect
Enzyme Commission (EC)FAD synthetase0Highly InformativeDirect

Document: EC annotation of SCOP domains

UniProtKB KeyWords (KW)

(show details)
KW termFDR (all)SDKW levelAnnotation (direct or inherited)
Molecular functionMagnesium0Least InformativeDirect
Molecular functionNucleotide-binding0Least InformativeDirect
Molecular functionMetal-binding0.0000000000001635Least InformativeDirect
Molecular functionFlavoprotein0Moderately InformativeDirect
Molecular functionFMN0InformativeDirect
Post-translational modificationTransferase0Least InformativeDirect
Post-translational modificationKinase0Moderately InformativeDirect

Document: KW annotation of SCOP domains

InterPro annotation
Cross references IPR015865 SSF82114 Protein matches
Abstract

This entry represents riboflavin kinase, which occurs as part of a bifunctional enzyme or a stand-alone enzyme.


InterPro database


PDBeMotif information about ligands, sequence and structure motifs
Cross references PDB entries
Ligand binding statistics
Nucleic-acid binding statistics
Occurrence of secondary structure elements
Occurrence of small 3D structural motifs

PDBeMotif resource

Jump to [ Top of page · SCOP classification · InterPro annotation · PDBeMotif links · Functional annotation · Gene Ontology (high-quality) · Gene Ontology (high-coverage) · Enzyme Commission (EC) · UniProtKB KeyWords (KW) ]

Internal database links

Browse genome assignments for this superfamily. The SUPERFAMILY hidden Markov model library has been used to carry out SCOP domain assignments to all genomes at the superfamily level.


Alignments of sequences to 5 models in this superfamily are available by clicking on the 'Alignments' icon above. PDB sequences less than 40% identical are shown by default, but any other sequence(s) may be aligned. Select PDB sequences, genome sequences, or paste in or upload your own sequences.


Browse and view proteins in genomes which have different domain combinations including a Riboflavin kinase-like domain.


Examine the distribution of domain superfamilies, or families, across the major taxonomic kingdoms or genomes within a kingdom. This gives an immediate impression of how superfamilies, or families, are restricted to certain kingdoms of life.


Explore domain occurrence network where nodes represent genomes and edges are domain architectures (shared between genomes) containing the superfamily of interest.

There are 5 hidden Markov models representing the Riboflavin kinase-like superfamily. Information on how the models are built, and plots showing hydrophobicity, match emmission probabilities and insertion/deletion probabilities can be inspected.


Jump to [ Top of page · SCOP classification · InterPro annotation · PDBeMotif links · Functional annotation · Gene Ontology (high-quality) · Gene Ontology (high-coverage) · Enzyme Commission (EC) · UniProtKB KeyWords (KW) · Internal database links ]