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DAK1/DegV-like superfamily

SCOP classification
Root:   SCOP hierarchy in SUPERFAMILY [ 0] (11)
Class:   Alpha and beta proteins (a/b) [ 51349] (147)
Fold:   DAK1/DegV-like [ 82548]
Superfamily:   DAK1/DegV-like [ 82549] (2)
Families:   DegV-like [ 82550] (2)
  DAK1 [ 109613] (2)


Superfamily statistics
Genomes (1,791) Uniprot 2017_06 genome PDB chains (SCOP 1.75)
Domains 4,448 26,578 7
Proteins 4,436 26,535 7


Functional annotation
General category Metabolism
Detailed category Polysaccharide metabolism and transport

Document:
Function annotation of SCOP domain superfamilies

Gene Ontology (high-quality)

(show details)
GO termFDR (singleton)FDR (all)SDFO levelAnnotation (direct or inherited)
Molecular Function (MF)transferase activity0.038330.00001318Least InformativeInherited
Molecular Function (MF)transferase activity, transferring phosphorus-containing groups0.00023590.00000000297Moderately InformativeDirect
Molecular Function (MF)kinase activity0.000076620.0000000002715InformativeDirect

Document: GO annotation of SCOP domains

Gene Ontology (high-coverage)

(show details)
GO term FDR (all) SDFO level Annotation (direct or inherited)
Biological Process (BP) primary metabolic process 0.1599 Least Informative Inherited
Biological Process (BP) single-organism metabolic process 0.03008 Least Informative Inherited
Biological Process (BP) single-organism cellular process 0.8194 Least Informative Inherited
Biological Process (BP) biological regulation 1 Least Informative Inherited
Biological Process (BP) carbohydrate metabolic process 0.0000000005376 Moderately Informative Direct
Biological Process (BP) organic substance catabolic process 0.00004185 Moderately Informative Direct
Biological Process (BP) single-organism catabolic process 0.001077 Moderately Informative Inherited
Biological Process (BP) regulation of signaling 0.03008 Moderately Informative Inherited
Biological Process (BP) regulation of cell communication 0.02958 Moderately Informative Inherited
Biological Process (BP) regulation of multicellular organismal process 0.04835 Moderately Informative Inherited
Biological Process (BP) negative regulation of cellular process 0.1628 Moderately Informative Inherited
Biological Process (BP) regulation of response to stimulus 0.0799 Moderately Informative Inherited
Biological Process (BP) cellular carbohydrate metabolic process 0.00000001512 Informative Direct
Biological Process (BP) carbohydrate catabolic process 0.0000004342 Informative Direct
Biological Process (BP) alcohol metabolic process 0.000006272 Informative Direct
Biological Process (BP) regulation of cytokine production 0.000006819 Informative Direct
Biological Process (BP) regulation of defense response 0.00002855 Informative Direct
Biological Process (BP) regulation of response to external stimulus 0.00005632 Informative Direct
Biological Process (BP) regulation of immune response 0.00007889 Informative Direct
Biological Process (BP) negative regulation of signaling 0.0002971 Informative Direct
Biological Process (BP) negative regulation of cell communication 0.000298 Informative Direct
Biological Process (BP) negative regulation of response to stimulus 0.0009185 Informative Direct
Biological Process (BP) regulation of intracellular signal transduction 0.001286 Informative Inherited
Biological Process (BP) polyol metabolic process 0.000000002254 Highly Informative Direct
Biological Process (BP) negative regulation of defense response 0.00000001814 Highly Informative Direct
Biological Process (BP) negative regulation of multi-organism process 0.00000001996 Highly Informative Direct
Biological Process (BP) negative regulation of response to external stimulus 0.00000009121 Highly Informative Direct
Biological Process (BP) negative regulation of intracellular signal transduction 0.000001658 Highly Informative Direct
Biological Process (BP) negative regulation of immune system process 0.000002053 Highly Informative Direct
Molecular Function (MF) transferase activity 0.00001318 Least Informative Direct
Molecular Function (MF) transferase activity, transferring phosphorus-containing groups 0.00000000297 Moderately Informative Direct
Molecular Function (MF) kinase activity 0.0000000002715 Informative Direct
Molecular Function (MF) phosphotransferase activity, alcohol group as acceptor 0.178 Informative Inherited

Document: GO annotation of SCOP domains

Enzyme Commission (EC)

(show details)
EC termFDR (all)SDEO levelAnnotation (direct or inherited)
Enzyme Commission (EC)Phosphotransferases with an alcohol group as accep0Moderately InformativeDirect

Document: EC annotation of SCOP domains

UniProtKB KeyWords (KW)

(show details)
KW termFDR (all)SDKW levelAnnotation (direct or inherited)
Biological processGlycerol metabolism0Highly InformativeDirect
Molecular functionLipid-binding0Moderately InformativeDirect
Molecular functionCobalt0.00004163InformativeDirect
Post-translational modificationTransferase0.148Least InformativeInherited
Post-translational modificationKinase0.0000000001387Moderately InformativeDirect

Document: KW annotation of SCOP domains

Jump to [ Top of page · SCOP classification · Functional annotation · Gene Ontology (high-quality) · Gene Ontology (high-coverage) · Enzyme Commission (EC) · UniProtKB KeyWords (KW) ]

Internal database links

Browse genome assignments for this superfamily. The SUPERFAMILY hidden Markov model library has been used to carry out SCOP domain assignments to all genomes at the superfamily level.


Alignments of sequences to 4 models in this superfamily are available by clicking on the 'Alignments' icon above. PDB sequences less than 40% identical are shown by default, but any other sequence(s) may be aligned. Select PDB sequences, genome sequences, or paste in or upload your own sequences.


Browse and view proteins in genomes which have different domain combinations including a DAK1/DegV-like domain.


Examine the distribution of domain superfamilies, or families, across the major taxonomic kingdoms or genomes within a kingdom. This gives an immediate impression of how superfamilies, or families, are restricted to certain kingdoms of life.


Explore domain occurrence network where nodes represent genomes and edges are domain architectures (shared between genomes) containing the superfamily of interest.

There are 4 hidden Markov models representing the DAK1/DegV-like superfamily. Information on how the models are built, and plots showing hydrophobicity, match emmission probabilities and insertion/deletion probabilities can be inspected.


Jump to [ Top of page · SCOP classification · Functional annotation · Gene Ontology (high-quality) · Gene Ontology (high-coverage) · Enzyme Commission (EC) · UniProtKB KeyWords (KW) · Internal database links ]