SUPERFAMILY 1.75 HMM library and genome assignments server

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Phosphoenolpyruvate mutase/Isocitrate lyase-like family

SCOP classification
Root:   SCOP hierarchy in SUPERFAMILY [ 0] (11)
Class:   Alpha and beta proteins (a/b) [ 51349] (147)
Fold:   TIM beta/alpha-barrel [ 51350] (33)
Superfamily:   Phosphoenolpyruvate/pyruvate domain [ 51621] (7)
Family:   Phosphoenolpyruvate mutase/Isocitrate lyase-like [ 88704] (3)


Family statistics
Genomes (1,557) Uniprot 2017_06 genome PDB chains (SCOP 1.75)
Domains 3,173 17,965 8
Proteins 3,172 17,955 8


Gene Ontology (high-quality)

(
show details)
GO termFDR (singleton)FDR (all)SDFO levelAnnotation (direct or inherited)
Biological Process (BP)single-organism metabolic process0.00000006590.0000000001175Least InformativeDirect
Biological Process (BP)primary metabolic process0.77771Least InformativeInherited
Biological Process (BP)single-organism cellular process0.00020110.00285Least InformativeInherited
Biological Process (BP)carbohydrate metabolic process0.000010410.00000004205Moderately InformativeDirect
Biological Process (BP)carboxylic acid metabolic process0.0000000000065740Moderately InformativeDirect
Biological Process (BP)single-organism catabolic process0.094640.03473Moderately InformativeInherited
Biological Process (BP)lipid metabolic process0.024490.004418Moderately InformativeInherited
Biological Process (BP)cellular catabolic process0.020740.007303Moderately InformativeInherited
Biological Process (BP)organic substance catabolic process0.053130.01079Moderately InformativeInherited
Biological Process (BP)cellular aldehyde metabolic process0.000000000010750InformativeDirect
Biological Process (BP)energy derivation by oxidation of organic compounds0.0000071320.000002911InformativeDirect
Biological Process (BP)lipid catabolic process0.00000003890.000000001678InformativeDirect
Biological Process (BP)cellular carbohydrate metabolic process0.0000000085790.0000000002545InformativeDirect
Biological Process (BP)small molecule catabolic process0.021610.005267InformativeInherited
Biological Process (BP)fatty acid metabolic process0.047140.09304InformativeInherited
Biological Process (BP)cellular lipid catabolic process0.000000064460.000000007747Highly InformativeDirect
Biological Process (BP)glyoxylate metabolic process0.0000000000067920Highly InformativeDirect
Biological Process (BP)monocarboxylic acid catabolic process0.0040340.0066Highly InformativeInherited
Molecular Function (MF)binding11Least InformativeInherited
Molecular Function (MF)lyase activity00Moderately InformativeDirect
Molecular Function (MF)metal ion binding0.7570.7767Moderately InformativeInherited
Molecular Function (MF)magnesium ion binding0.000081670.000005882InformativeDirect
Molecular Function (MF)carbon-carbon lyase activity0.00000000057060.000000000002727InformativeDirect
Molecular Function (MF)oxo-acid-lyase activity00Highly InformativeDirect

Document: GO annotation of SCOP domains

Gene Ontology (high-coverage)

(show details)
GO term FDR (all) SDFO level Annotation (direct or inherited)
Biological Process (BP) single-organism metabolic process 0.0000000001175 Least Informative Direct
Biological Process (BP) primary metabolic process 1 Least Informative Inherited
Biological Process (BP) single-organism cellular process 0.00285 Least Informative Inherited
Biological Process (BP) carbohydrate metabolic process 0.00000004205 Moderately Informative Direct
Biological Process (BP) carboxylic acid metabolic process 0 Moderately Informative Direct
Biological Process (BP) single-organism catabolic process 0.03473 Moderately Informative Inherited
Biological Process (BP) lipid metabolic process 0.004418 Moderately Informative Inherited
Biological Process (BP) cellular catabolic process 0.007303 Moderately Informative Inherited
Biological Process (BP) organic substance catabolic process 0.01079 Moderately Informative Inherited
Biological Process (BP) cellular aldehyde metabolic process 0 Informative Direct
Biological Process (BP) energy derivation by oxidation of organic compounds 0.000002911 Informative Direct
Biological Process (BP) lipid catabolic process 0.000000001678 Informative Direct
Biological Process (BP) cellular carbohydrate metabolic process 0.0000000002545 Informative Direct
Biological Process (BP) small molecule catabolic process 0.005267 Informative Inherited
Biological Process (BP) fatty acid metabolic process 0.09304 Informative Inherited
Biological Process (BP) cellular lipid catabolic process 0.000000007747 Highly Informative Direct
Biological Process (BP) glyoxylate metabolic process 0 Highly Informative Direct
Biological Process (BP) monocarboxylic acid catabolic process 0.0066 Highly Informative Inherited
Molecular Function (MF) binding 1 Least Informative Inherited
Molecular Function (MF) lyase activity 0 Moderately Informative Direct
Molecular Function (MF) metal ion binding 0.7767 Moderately Informative Inherited
Molecular Function (MF) magnesium ion binding 0.000005882 Informative Direct
Molecular Function (MF) carbon-carbon lyase activity 0.000000000002727 Informative Direct
Molecular Function (MF) oxo-acid-lyase activity 0 Highly Informative Direct

Document: GO annotation of SCOP domains

Enzyme Commission (EC)

(show details)
EC termFDR (all)SDEO levelAnnotation (direct or inherited)
Enzyme Commission (EC)Lyases0Least InformativeDirect
Enzyme Commission (EC)Carboxy-lyases1Moderately InformativeInherited
Enzyme Commission (EC)Oxo-acid-lyases0InformativeDirect

Document: EC annotation of SCOP domains

UniProtKB KeyWords (KW)

(show details)
KW termFDR (all)SDKW levelAnnotation (direct or inherited)
Biological processTricarboxylic acid cycle0Highly InformativeDirect
Cellular componentPeroxisome0InformativeDirect
Molecular functionMetal-binding0Least InformativeDirect
Molecular functionMagnesium0Moderately InformativeDirect
Post-translational modificationLyase0Moderately InformativeDirect
Post-translational modificationDecarboxylase0.00002355Highly InformativeDirect

Document: KW annotation of SCOP domains

Jump to [ Top of page · SCOP classification · Gene Ontology (high-quality) · Gene Ontology (high-coverage) · Enzyme Commission (EC) · UniProtKB KeyWords (KW) ]

Internal database links

   
Superfamily level     Family level

Browse genome assignments for this superfamily. The SUPERFAMILY hidden Markov model library has been used to carry out SCOP domain assignments to all genomes at the superfamily level.


   
Superfamily level     Family level

Alignments of sequences to 24 models in this superfamily are available by clicking on the 'Alignments' icon above. PDB sequences less than 40% identical are shown by default, but any other sequence(s) may be aligned. Select PDB sequences, genome sequences, or paste in or upload your own sequences.


Superfamily level

Browse and view proteins in genomes which have different domain combinations including a Phosphoenolpyruvate/pyruvate domain domain.


   
Superfamily level     Family level

Examine the distribution of domain superfamilies, or families, across the major taxonomic kingdoms or genomes within a kingdom. This gives an immediate impression of how superfamilies, or families, are restricted to certain kingdoms of life.


Jump to [ Top of page · SCOP classification · Gene Ontology (high-quality) · Gene Ontology (high-coverage) · Enzyme Commission (EC) · UniProtKB KeyWords (KW) · Internal database links ]