SUPERFAMILY 1.75 HMM library and genome assignments server

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Pre-PUA domain superfamily

SCOP classification
Root:   SCOP hierarchy in SUPERFAMILY [ 0] (11)
Class:   Alpha and beta proteins (a+b) [ 53931] (376)
Fold:   Cystatin-like [ 54402] (7)
Superfamily:   Pre-PUA domain [ 88802] (5)
Families:   Archaeosine tRNA-guanine transglycosylase, C2 domain [ 88803]
  Hypothetical protein Ta1423, N-terminal domain [ 102820]
  Nip7p homolog, N-terminal domain [ 110832]
  Hypothetical protein APE0525, N-terminal domain [ 143004]
  AF0587 pre C-terminal domain-like [ 160053]

Superfamily statistics
Genomes (637) Uniprot 2017_06 genome PDB chains (SCOP 1.75)
Domains 937 2,765 7
Proteins 931 2,756 7

Functional annotation
General category Regulation
Detailed category RNA binding, metabolism and transport

Function annotation of SCOP domain superfamilies

UniProtKB KeyWords (KW)

(show details)
KW termFDR (all)SDKW levelAnnotation (direct or inherited)
Biological processtRNA processing0InformativeDirect
Biological processRibosome biogenesis0.0000000002182InformativeDirect
Cellular componentNucleus0.0001838Least InformativeDirect
Molecular functionZinc0Least InformativeDirect
Molecular functionMetal-binding0.000000000006962Least InformativeDirect
Post-translational modificationTransferase0.0000000000005018Least InformativeDirect
Post-translational modificationGlycosyltransferase0InformativeDirect

Document: KW annotation of SCOP domains

Jump to [ Top of page · SCOP classification · Functional annotation · UniProtKB KeyWords (KW) ]

Internal database links

Browse genome assignments for this superfamily. The SUPERFAMILY hidden Markov model library has been used to carry out SCOP domain assignments to all genomes at the superfamily level.

Alignments of sequences to 5 models in this superfamily are available by clicking on the 'Alignments' icon above. PDB sequences less than 40% identical are shown by default, but any other sequence(s) may be aligned. Select PDB sequences, genome sequences, or paste in or upload your own sequences.

Browse and view proteins in genomes which have different domain combinations including a Pre-PUA domain domain.

Examine the distribution of domain superfamilies, or families, across the major taxonomic kingdoms or genomes within a kingdom. This gives an immediate impression of how superfamilies, or families, are restricted to certain kingdoms of life.

Explore domain occurrence network where nodes represent genomes and edges are domain architectures (shared between genomes) containing the superfamily of interest.

There are 5 hidden Markov models representing the Pre-PUA domain superfamily. Information on how the models are built, and plots showing hydrophobicity, match emmission probabilities and insertion/deletion probabilities can be inspected.

Jump to [ Top of page · SCOP classification · Functional annotation · UniProtKB KeyWords (KW) · Internal database links ]