dcGO - A comprehensive domain-centric ontology resource for post-genomic research on functions, phenotypes, diseases and more   
  
  

Funding and Publications

  • Funding
    • Tools for Ontology Annotation: dcGO

      Fang H, Gough J.

      BBSRC Tools and Resources Development Fund: BB/L018543/1

  • Main publications
    • dcGO: database of domain-centric ontologies on functions, phenotypes, diseases and more

      Fang H, Gough J.

      Nucleic Acids Research 2013, 41(Database issue):D536-44.

      PubMed ID: 23161684; DOI: 10.1093/nar/gks1080

      dcGOR: an R package for analysing ontologies and protein domain annotations

      Fang H.

      PLoS Computational Biology 2014, 10(10):e1003929.

      PubMed ID: 25356683; DOI: 10.1371/journal.pcbi.1003929

  • Relevant publications
    • Function-selective domain architecture plasticity potentials in eukaryotic genome evolution

      Linkeviciute V, Rackham OJ, Gough J, Oates ME, Fang H.

      Biochimie 2015 (In Press).

      DOI: 10.1016/j.biochi.2015.05.003

      The evolution of human cells in terms of protein innovation

      Sardar AJ, Oates ME, Fang H, Forrest ARR, Kawaji H, Gough J, Rackham OJ.

      Molecular Biology and Evolution 2014, 31(6):1364-1374.

      PubMed ID: 24692656; DOI: 10.1093/molbev/mst139

      A daily-updated tree of (sequenced) life as a reference for genome research

      Fang H, Oates ME, Pethica RB, Greenwood JM, Sardar AJ, Rackham OJ, Donoghue PC, Stamatakis A, de Lima Morais DA, Gough J.

      Scientific Reports 2013, 3:2015.

      PubMed ID: 23778980; DOI: 10.1038/srep02015

      A disease-drug-phenotype matrix inferred by walking on a functional domain network

      Fang H, Gough J.

      Molecular BioSystems 2013, 9(7):1686-96.

      PubMed ID: 23462907; DOI: 10.1039/c3mb25495j

      A domain-centric solution to functional genomics via dcGO Predictor

      Fang H, Gough J.

      BMC Bioinformatics 2013, 14(Suppl 3):S9.

      PubMed ID: 23514627; DOI: 10.1186/1471-2105-14-S3-S9

      A large-scale evaluation of computational protein function prediction

      Radivojac P, Clark WT, Oron TR, Schnoes AM, Wittkop T, Sokolov A, Graim K, Funk C, Verspoor K, Ben-Hur A, Pandey G, Yunes JM, Talwalkar AS, Repo S, Souza ML, Piovesan D, Casadio R, Wang Z, Cheng J, Fang H, Gough J, Koskinen P, Toronen P, Nokso-Koivisto J, Holm L, Cozzetto D, Buchan DW, Bryson K, Jones DT, Limaye B, Inamdar H, Datta A, Manjari SK, Joshi R, Chitale M, Kihara D, Lisewski AM, Erdin S, Venner E, Lichtarge O, Rentzsch R, Yang H, Romero AE, Bhat P, Paccanaro A, Hamp T, Kassner R, Seemayer S, Vicedo E, Schaefer C, Achten D, Auer F, Boehm A, Braun T, Hecht M, Heron M, Honigschmid P, Hopf TA, Kaufmann S, Kiening M, Krompass D, Landerer C, Mahlich Y, Roos M, Bjorne J, Salakoski T, Wong A, Shatkay H, Gatzmann F, Sommer I, Wass MN, Sternberg MJ, Skunca N, Supek F, Bosnjak M, Panov P, Dzeroski S, Smuc T, Kourmpetis YA, van Dijk AD, Braak CJ, Zhou Y, Gong Q, Dong X, Tian W, Falda M, Fontana P, Lavezzo E, Di Camillo B, Toppo S, Lan L, Djuric N, Guo Y, Vucetic S, Bairoch A, Linial M, Babbitt PC, Brenner SE, Orengo C, Rost B, Mooney SD, Friedberg I.

      Nature Methods 2013, 10(3):221-7.

      PubMed ID: 23353650; DOI: 10.1038/nmeth.2340

      SUPERFAMILY 1.75 including a domain-centric gene ontology method

      de Lima Morais DA, Fang H, Rackham OJ, Wilson D, Pethica R, Chothia C, Gough J.

      Nucleic Acids Research 2011, 39(Database issue):D427-34.

      PubMed ID: 21062816; DOI: 10.1093/nar/gkq1130