Family Assignments

Domains Proteins SCOP Link Families
10 10 SCOP 52375 Class I aminoacyl-tRNA synthetases (RS), catalytic domain
10 10 SCOP 55682 Class II aminoacyl-tRNA synthetase (aaRS)-like, catalytic domain
8 6 SCOP 81269 Extended AAA-ATPase domain
6 6 SCOP 52686 ABC transporter ATPase domain-like
5 5 SCOP 52592 G proteins
5 4 SCOP 81268 Tandem AAA-ATPase domain
4 4 SCOP 52318 Class I glutamine amidotransferases (GAT)
4 4 SCOP 52652 Nitrogenase iron protein-like
4 4 SCOP 52670 RecA protein-like (ATPase-domain)
4 2 SCOP 53068 Actin/HSP70
4 4 SCOP 53687 Tryptophan synthase beta subunit-like PLP-dependent enzymes
4 3 SCOP 56067 BC ATP-binding domain-like
3 3 SCOP 48558 L-aspartase/fumarase
3 3 SCOP 51883 Aminoacid dehydrogenase-like, C-terminal domain
3 2 SCOP 52441 BC N-terminal domain-like
3 3 SCOP 52778 CAT-like
3 3 SCOP 53384 AAT-like
3 3 SCOP 53402 Cystathionine synthase-like
3 3 SCOP 53417 GABA-aminotransferase-like
3 3 SCOP 55348 GAPDH-like
3 1 SCOP 55974 S-adenosylmethionine synthetase
2 2 SCOP 47324 Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases
2 2 SCOP 50282 Cold shock DNA-binding domain-like
2 2 SCOP 50448 Elongation factors
2 2 SCOP 51367 Histidine biosynthesis enzymes
2 2 SCOP 51381 Tryptophan biosynthesis enzymes
2 2 SCOP 51570 Class I aldolase
2 2 SCOP 52211 Succinyl-CoA synthetase domains
2 1 SCOP 53089 Glycerol kinase
2 2 SCOP 53138 Ribosomal protein L18 and S11
2 2 SCOP 53329 Formyltransferase
2 2 SCOP 53660 Dimeric isocitrate & isopropylmalate dehydrogenases
2 2 SCOP 53733 Aconitase iron-sulfur domain
2 2 SCOP 53851 Phosphate binding protein-like
2 1 SCOP 53902 Thiolase-related
2 2 SCOP 54212 Translational machinery components
2 1 SCOP 54229 Ribonuclease PH domain 1-like
2 2 SCOP 55209 Enolpyruvate transferase, EPT
2 2 SCOP 55425 FAD/NAD-linked reductases, dimerisation (C-terminal) domain
2 2 SCOP 55879 DNA gyrase/MutL, N-terminal domain
2 1 SCOP 56015 Nitrite and sulphite reductase 4Fe-4S domain-like
2 2 SCOP 56236 Class II glutamine amidotransferases
2 2 SCOP 75621 Release factor
2 2 SCOP 89572 Biotin dependent carboxylase carboxyltransferase domain
2 2 SCOP 90124 ABC transporter transmembrane region
2 1 SCOP 110384 Cobalamin-independent methionine synthase
2 1 SCOP 142678 Glycine dehydrogenase subunits (GDC-P)
2 2 SCOP 142721 PyrH-like
1 1 SCOP 46566 Chaperone J-domain
1 1 SCOP 46947 Ribosomal protein S13
1 1 SCOP 47241 Ferritin
1 1 SCOP 47918 C-terminal domain of alpha and beta subunits of F1 ATP synthase
1 1 SCOP 47974 Ribosomal protein S7
1 1 SCOP 48154 Mismatch glycosylase
1 1 SCOP 48257 Citrate synthase
1 1 SCOP 48335 DNA repair protein MutS, domain III
1 1 SCOP 48593 GroEL chaperone, ATPase domain
1 1 SCOP 50114 C-terminal domain of ribosomal protein L2
1 1 SCOP 50194 Ribosomal protein L14
1 1 SCOP 50325 Inorganic pyrophosphatase
1 1 SCOP 50461 Ribosomal protein L3
1 1 SCOP 50466 EF-Tu/eEF-1alpha/eIF2-gamma C-terminal domain
1 1 SCOP 50476 PNP-oxidase like
1 1 SCOP 50495 Prokaryotic proteases
1 1 SCOP 50678 ValRS/IleRS/LeuRS editing domain
1 1 SCOP 50719 Gln-tRNA synthetase (GlnRS), C-terminal (anticodon-binding) domain
1 1 SCOP 51165 Tetrahydrodipicolinate-N-succinlytransferase, THDP-succinlytransferase, DapD
1 1 SCOP 51231 Biotinyl/lipoyl-carrier proteins and domains
1 1 SCOP 51247 BC C-terminal domain-like
1 1 SCOP 51279 Urease, beta-subunit
1 1 SCOP 51284 dUTPase-like
1 1 SCOP 51339 alpha-Subunit of urease
1 1 SCOP 51352 Triosephosphate isomerase (TIM)
1 1 SCOP 51372 D-ribulose-5-phosphate 3-epimerase
1 1 SCOP 51375 Decarboxylase
1 1 SCOP 51396 FMN-linked oxidoreductases
1 1 SCOP 51413 Inosine monophosphate dehydrogenase (IMPDH)
1 1 SCOP 51420 Alanine racemase-like, N-terminal domain
1 1 SCOP 51427 "Hypothetical" protein ybl036c
1 1 SCOP 51560 alpha-subunit of urease, catalytic domain
1 1 SCOP 51591 Class II FBP aldolase
1 1 SCOP 51599 Class I DAHP synthetase
1 1 SCOP 51605 Enolase
1 1 SCOP 51714 tRNA-guanine transglycosylase
1 1 SCOP 51718 Dihydropteroate synthetase
1 1 SCOP 51731 Methylenetetrahydrofolate reductase
1 1 SCOP 51751 Tyrosine-dependent oxidoreductases
1 1 SCOP 51800 Glyceraldehyde-3-phosphate dehydrogenase-like, N-terminal domain
1 1 SCOP 51848 LDH N-terminal domain-like
1 1 SCOP 51900 CoA-binding domain
1 1 SCOP 51943 FAD/NAD-linked reductases, N-terminal and central domains
1 1 SCOP 52002 R1 subunit of ribonucleotide reductase, C-terminal domain
1 1 SCOP 52017 LeuD-like
1 1 SCOP 52022 Carbamoyl phosphate synthetase, small subunit N-terminal domain
1 1 SCOP 52030 GroEL-like chaperone, apical domain
1 1 SCOP 52081 Ribosomal proteins L15p and L18e
1 1 SCOP 52097 Clp protease, ClpP subunit
1 1 SCOP 52103 Crotonase-like
1 1 SCOP 52122 Lumazine synthase
1 1 SCOP 52142 Uracil-DNA glycosylase
1 1 SCOP 52152 FabD-like
1 1 SCOP 52162 Ribosomal protein L13
1 1 SCOP 52167 Ribosomal protein L4
1 1 SCOP 52256 N5-CAIR mutase (phosphoribosylaminoimidazole carboxylase, PurE)
1 1 SCOP 52305 Type II 3-dehydroquinate dehydratase
1 1 SCOP 52314 Ribosomal protein S2
1 1 SCOP 52397 Adenylyltransferase
1 1 SCOP 52403 N-type ATP pyrophosphatases
1 1 SCOP 52410 PAPS reductase-like
1 1 SCOP 52419 Nucleoside phosphorylase/phosphoribosyltransferase catalytic domain
1 1 SCOP 52491 Tubulin, GTPase domain
1 1 SCOP 52541 Nucleotide and nucleoside kinases
1 1 SCOP 52901 Glutathione peroxidase-like
1 1 SCOP 52955 Anticodon-binding domain of Class II aaRS
1 1 SCOP 53099 Ribonuclease H
1 1 SCOP 53168 Purine and uridine phosphorylases
1 1 SCOP 53204 Bacterial dinuclear zinc exopeptidases
1 1 SCOP 53224 Aminoacid dehydrogenases
1 1 SCOP 53240 Malic enzyme N-domain
1 1 SCOP 53272 Phosphoribosyltransferases (PRTases)
1 1 SCOP 53296 Phosphoribosylpyrophosphate synthetase-like
1 1 SCOP 53624 MurCDEF
1 1 SCOP 53629 Folylpolyglutamate synthetase
1 1 SCOP 53672 Aspartate/ornithine carbamoyltransferase
1 1 SCOP 53698 double-SIS domain
1 1 SCOP 53721 ALDH-like
1 1 SCOP 53749 Phosphoglycerate kinase
1 1 SCOP 53760 Peptidoglycan biosynthesis glycosyltransferase MurG
1 1 SCOP 53791 Tetrapyrrole methylase
1 1 SCOP 53796 PEP carboxykinase C-terminal domain
1 1 SCOP 54112 Urease, gamma-subunit
1 1 SCOP 54224 DNA gyrase/MutL, second domain
1 1 SCOP 54232 GHMP Kinase, N-terminal domain
1 1 SCOP 54571 Ribosomal protein S19
1 1 SCOP 54632 CBS-domain pair
1 1 SCOP 54720 Fe,Mn superoxide dismutase (SOD), C-terminal domain
1 1 SCOP 54811 GMP synthetase C-terminal dimerisation domain
1 1 SCOP 54815 Prokaryotic type KH domain (KH-domain type II)
1 1 SCOP 54822 Ribosomal protein S3 C-terminal domain
1 1 SCOP 54827 Enolase N-terminal domain-like
1 1 SCOP 54920 Nucleoside diphosphate kinase, NDK
1 1 SCOP 54981 EF-G/eEF-2 domains III and V
1 1 SCOP 55000 Ribosomal protein S10
1 1 SCOP 55121 Pseudouridine synthase I TruA
1 1 SCOP 55178 Ribosomal protein S4
1 1 SCOP 55195 Ribosome recycling factor, RRF
1 1 SCOP 55272 DNA repair protein MutS, domain I
1 1 SCOP 55283 Ribosomal protein L5
1 1 SCOP 55299 YjgF/L-PSP
1 1 SCOP 55327 PurM N-terminal domain-like
1 1 SCOP 55363 Homoserine dehydrogenase-like
1 1 SCOP 55621 GTP cyclohydrolase I
1 1 SCOP 55832 Thymidylate synthase/dCMP hydroxymethylase
1 1 SCOP 55875 Heat shock protein 90, HSP90, N-terminal domain
1 1 SCOP 55921 Creatinase/aminopeptidase
1 1 SCOP 56038 B3/B4 domain of PheRS, PheT
1 1 SCOP 56043 PurM C-terminal domain-like
1 1 SCOP 56048 Ribosomal protein S8
1 1 SCOP 56054 Ribosomal protein L6
1 1 SCOP 56081 Succinyl-CoA synthetase, beta-chain, N-terminal domain
1 1 SCOP 56096 Adenylation domain of NAD+-dependent DNA ligase
1 1 SCOP 56105 SAICAR synthase
1 1 SCOP 56184 Uridine diphospho-N-Acetylenolpyruvylglucosamine reductase (MurB), N-terminal domain
1 1 SCOP 56220 DNase I-like
1 1 SCOP 56323 ADC synthase
1 1 SCOP 56328 Lactate & malate dehydrogenases, C-terminal domain
1 1 SCOP 56421 Peptide deformylase
1 1 SCOP 56656 Inositol monophosphatase/fructose-1,6-bisphosphatase-like
1 1 SCOP 56713 Prokaryotic type I DNA topoisomerase
1 1 SCOP 56720 Type II DNA topoisomerase
1 1 SCOP 56732 DNA primase DnaG catalytic core
1 1 SCOP 56753 D-aminoacid aminotransferase-like PLP-dependent enzymes
1 1 SCOP 56797 Dehydroquinate synthase, DHQS
1 1 SCOP 56809 Ribosomal protein L1
1 1 SCOP 56895 Aquaporin-like
1 1 SCOP 63893 Pyridoxine 5'-phosphate synthase
1 1 SCOP 63971 Inosicase
1 1 SCOP 64006 Undecaprenyl diphosphate synthase
1 1 SCOP 64159 2,3-Bisphosphoglycerate-independent phosphoglycerate mutase, substrate-binding domain
1 1 SCOP 64162 2,3-Bisphosphoglycerate-independent phosphoglycerate mutase, catalytic domain
1 1 SCOP 64168 SurE-like
1 1 SCOP 64198 AICAR transformylase domain of bifunctional purine biosynthesis enzyme ATIC
1 1 SCOP 64264 Prokaryotic ribosomal protein L17
1 1 SCOP 64372 3,4-dihydroxy-2-butanone 4-phosphate synthase, DHBP synthase, RibB
1 1 SCOP 64485 RNA-polymerase beta
1 1 SCOP 64490 RNA-polymerase beta-prime
1 1 SCOP 68924 PEP carboxykinase N-terminal domain
1 1 SCOP 69602 L-histidinol dehydrogenase HisD
1 1 SCOP 69746 Pseudouridine synthase II TruB
1 1 SCOP 74732 Ribosomal protein L20
1 1 SCOP 74983 Small protein B (SmpB)
1 1 SCOP 75292 YjeF C-terminal domain-like
1 1 SCOP 75297 N-acetyl-l-glutamate kinase
1 1 SCOP 75459 Pseudouridine synthase RsuA/RluD
1 1 SCOP 75626 YebC-like
1 1 SCOP 82052 Obg GTP-binding protein N-terminal domain
1 1 SCOP 82267 TatD Mg-dependent DNase-like
1 1 SCOP 82359 PP-loop ATPase
1 1 SCOP 82583 G domain-linked domain
1 1 SCOP 82661 Poly A polymerase head domain-like
1 1 SCOP 88683 Eukaryotic ODC-like
1 1 SCOP 88724 Pyruvate oxidase and decarboxylase Pyr module
1 1 SCOP 88741 Branched-chain alpha-keto acid dehydrogenase Pyr module
1 1 SCOP 88749 Pyruvate oxidase and decarboxylase PP module
1 1 SCOP 88760 TK-like PP module
1 1 SCOP 88766 Branched-chain alpha-keto acid dehydrogenase PP module
1 1 SCOP 89624 Ribose/Galactose isomerase RpiB/AlsB
1 1 SCOP 89629 tRNA(m1G37)-methyltransferase TrmD
1 1 SCOP 89800 Deoxycytidylate deaminase-like
1 1 SCOP 100921 Heat shock protein 70kD (HSP70), peptide-binding domain
1 1 SCOP 101354 Putative anticodon-binding domain of alanyl-tRNA synthetase (AlaRS)
1 1 SCOP 101905 GyrA/ParC C-terminal domain-like
1 1 SCOP 101961 Stabilizer of iron transporter SufD
1 1 SCOP 102656 PdxA-like
1 1 SCOP 102663 Phosphotransacetylase
1 1 SCOP 102706 NIF3 (NGG1p interacting factor 3)-like
1 1 SCOP 102755 Hsp90 middle domain
1 1 SCOP 102769 ATP-dependent protease Lon (La), catalytic domain
1 1 SCOP 103026 Aminomethyltransferase folate-binding domain
1 1 SCOP 103264 Chorismate synthase, AroC
1 1 SCOP 110910 Monomeric nicotinate phosphoribosyltransferase C-terminal domain
1 1 SCOP 111338 QueA-like
1 1 SCOP 117888 Ribosomal protein L16p
1 1 SCOP 118216 Proton glutamate symport protein
1 1 SCOP 140479 LemA-like
1 1 SCOP 140991 FtsH protease domain-like
1 1 SCOP 143598 YojJ-like
1 1 SCOP 143642 LplA-like
1 1 SCOP 143916 RNase Z-like
1 1 SCOP 143976 lvD/EDD N-terminal domain-like
1 1 SCOP 159112 RNB domain-like
1 1 SCOP 159832 PBP transglycosylase domain-like
1 1 SCOP 161094 MgtE membrane domain-like

The following families have one or more weak hits: