Family Assignments

Domains Proteins SCOP Link Families
58 58 SCOP 88854 Protein kinases, catalytic subunit
39 39 SCOP 52592 G proteins
36 36 SCOP 48265 Cytochrome P450
22 16 SCOP 52686 ABC transporter ATPase domain-like
20 17 SCOP 81268 Tandem AAA-ATPase domain
18 17 SCOP 52641 Motor proteins
17 14 SCOP 51751 Tyrosine-dependent oxidoreductases
17 17 SCOP 56802 Acetyl-CoA synthetase-like
15 10 SCOP 50646 Pepsin-like
15 11 SCOP 53068 Actin/HSP70
13 11 SCOP 81269 Extended AAA-ATPase domain
12 11 SCOP 51446 Amylase, catalytic domain
12 9 SCOP 56575 Serpins
11 11 SCOP 47114 Nucleosome core histones
10 10 SCOP 53402 Cystathionine synthase-like
9 8 SCOP 51396 FMN-linked oxidoreductases
9 9 SCOP 53417 GABA-aminotransferase-like
9 9 SCOP 55308 Tubulin, C-terminal domain
9 9 SCOP 69565 Pyridoxal-dependent decarboxylase
8 4 SCOP 46967 Spectrin repeat
8 7 SCOP 48404 Ankyrin repeat
8 8 SCOP 50979 WD40-repeat
8 8 SCOP 52375 Class I aminoacyl-tRNA synthetases (RS), catalytic domain
8 8 SCOP 53506 Gastric lipase
8 8 SCOP 53577 Pancreatic lipase, N-terminal domain
8 8 SCOP 54496 UBC-related
7 7 SCOP 52575 PAPS sulfotransferase
7 6 SCOP 53721 ALDH-like
7 7 SCOP 55074 Adenylyl and guanylyl cyclase catalytic domain
7 7 SCOP 56251 Proteasome subunits
7 4 SCOP 63412 MPP-like
6 6 SCOP 46832 Forkhead DNA-binding domain
6 6 SCOP 47577 Calponin-homology domain, CH-domain
6 5 SCOP 48372 Armadillo repeat
6 6 SCOP 50892 Cyclophilin (peptidylprolyl isomerase)
6 3 SCOP 51534 Type II chitinase
6 6 SCOP 51736 Alcohol dehydrogenase-like, C-terminal domain
6 6 SCOP 52491 Tubulin, GTPase domain
6 6 SCOP 52541 Nucleotide and nucleoside kinases
6 6 SCOP 53851 Phosphate binding protein-like
6 6 SCOP 55682 Class II aminoacyl-tRNA synthetase (aaRS)-like, catalytic domain
6 5 SCOP 82568 Ubiquitin carboxyl-terminal hydrolase, UCH
5 2 SCOP 47221 alpha-catenin/vinculin
5 5 SCOP 47502 Calmodulin-like
5 5 SCOP 48509 Nuclear receptor ligand-binding domain
5 5 SCOP 48548 PDEase
5 5 SCOP 51070 Carbonic anhydrase
5 4 SCOP 52773 Histone deacetylase, HDAC
5 5 SCOP 52901 Glutathione peroxidase-like
5 5 SCOP 53384 AAT-like
5 5 SCOP 54002 Papain-like
5 5 SCOP 54929 Canonical RBD
5 5 SCOP 55502 Neutral endopeptidase (neprilysin)
5 5 SCOP 56205 Hect, E3 ligase catalytic domain
5 5 SCOP 56310 Protein serine/threonine phosphatase
5 5 SCOP 56328 Lactate & malate dehydrogenases, C-terminal domain
4 4 SCOP 46748 Paired domain
4 4 SCOP 47617 Glutathione S-transferase (GST), C-terminal domain
4 4 SCOP 48066 DBL homology domain (DH-domain)
4 4 SCOP 48132 Myeloperoxidase-like
4 3 SCOP 48446 14-3-3 protein
4 4 SCOP 50448 Elongation factors
4 4 SCOP 50730 Pleckstrin-homology domain (PH domain)
4 4 SCOP 51210 cAMP-binding domain
4 4 SCOP 51848 LDH N-terminal domain-like
4 4 SCOP 52670 RecA protein-like (ATPase-domain)
4 4 SCOP 52805 Higher-molecular-weight phosphotyrosine protein phosphatases
4 4 SCOP 53188 Pancreatic carboxypeptidases
4 3 SCOP 53785 Phosphofructokinase
4 2 SCOP 55327 PurM N-terminal domain-like
4 4 SCOP 55505 Neurolysin-like
4 4 SCOP 55516 Astacin
4 3 SCOP 55974 S-adenosylmethionine synthetase
4 4 SCOP 56171 Phoshoinositide 3-kinase (PI3K), catalytic domain
4 2 SCOP 81290 Filamin repeat (rod domain)
4 3 SCOP 88766 Branched-chain alpha-keto acid dehydrogenase PP module
4 3 SCOP 100908 MIF4G domain-like
3 3 SCOP 46690 Homeodomain
3 3 SCOP 46775 ARID domain
3 3 SCOP 47096 HMG-box
3 3 SCOP 47241 Ferritin
3 3 SCOP 47371 Bromodomain
3 3 SCOP 47918 C-terminal domain of alpha and beta subunits of F1 ATP synthase
3 3 SCOP 48098 Regulator of G-protein signaling, RGS
3 3 SCOP 48385 HEAT repeat
3 2 SCOP 48453 Tetratricopeptide repeat (TPR)
3 3 SCOP 50136 Alcohol dehydrogenase-like, N-terminal domain
3 3 SCOP 50755 Phosphotyrosine-binding domain (PTB)
3 3 SCOP 51800 Glyceraldehyde-3-phosphate dehydrogenase-like, N-terminal domain
3 3 SCOP 51830 Formate/glycerate dehydrogenases, NAD-domain
3 2 SCOP 52211 Succinyl-CoA synthetase domains
3 3 SCOP 52432 ETFP subunits
3 2 SCOP 53083 Hexokinase
3 3 SCOP 53168 Purine and uridine phosphorylases
3 3 SCOP 53272 Phosphoribosyltransferases (PRTases)
3 3 SCOP 53614 Ribokinase-like
3 3 SCOP 53650 Alkaline phosphatase
3 3 SCOP 53928 Cytidine deaminase
3 3 SCOP 54212 Translational machinery components
3 1 SCOP 54237 Ubiquitin-related
3 3 SCOP 54632 CBS-domain pair
3 3 SCOP 55551 SH2 domain
3 3 SCOP 55730 N-acetyl transferase, NAT
3 3 SCOP 56067 BC ATP-binding domain-like
3 2 SCOP 56656 Inositol monophosphatase/fructose-1,6-bisphosphatase-like
3 3 SCOP 56895 Aquaporin-like
3 3 SCOP 57721 Nuclear receptor
3 3 SCOP 64422 Inositol polyphosphate 5-phosphatase (IPP5)
3 3 SCOP 74789 Cullin repeat
3 2 SCOP 75585 Noncollagenous (NC1) domain of collagen IV
3 3 SCOP 81316 T-box
3 3 SCOP 82497 DPP6 catalytic domain-like
3 3 SCOP 100921 Heat shock protein 70kD (HSP70), peptide-binding domain
3 3 SCOP 102422 Myotubularin-like phosphatases
3 3 SCOP 103507 Mitochondrial carrier
3 3 SCOP 111348 Rap/Ran-GAP
3 3 SCOP 117282 Kelch motif
3 3 SCOP 117702 Polypeptide N-acetylgalactosaminyltransferase 1, N-terminal domain
2 2 SCOP 47204 Medium chain acyl-CoA dehydrogenase-like, C-terminal domain
2 2 SCOP 47770 Pointed domain
2 1 SCOP 47924 Ypt/Rab-GAP domain of gyp1p
2 1 SCOP 48226 Class I alpha-1;2-mannosidase, catalytic domain
2 2 SCOP 48351 BCR-homology GTPase activation domain (BH-domain)
2 2 SCOP 48426 Sec7 domain
2 2 SCOP 48558 L-aspartase/fumarase
2 2 SCOP 49266 Fibronectin type III
2 2 SCOP 49330 Cu,Zn superoxide dismutase-like
2 2 SCOP 49575 Synaptotagmin-like (S variant)
2 2 SCOP 49880 SMAD domain
2 1 SCOP 50263 Single strand DNA-binding domain, SSB
2 2 SCOP 50282 Cold shock DNA-binding domain-like
2 2 SCOP 50678 ValRS/IleRS/LeuRS editing domain
2 1 SCOP 50764 Ran-binding domain
2 2 SCOP 50917 Rap30/74 interaction domains
2 2 SCOP 51247 BC C-terminal domain-like
2 2 SCOP 51431 Aldo-keto reductases (NADP)
2 2 SCOP 51521 Family 1 of glycosyl hydrolase
2 1 SCOP 52002 R1 subunit of ribonucleotide reductase, C-terminal domain
2 2 SCOP 52201 Toll/Interleukin receptor TIR domain
2 2 SCOP 52318 Class I glutamine amidotransferases (GAT)
2 2 SCOP 52325 DJ-1/PfpI
2 2 SCOP 52508 Homo-oligomeric flavin-containing Cys decarboxylases, HFCD
2 2 SCOP 52652 Nitrogenase iron protein-like
2 2 SCOP 52744 Subtilases
2 2 SCOP 52800 Dual specificity phosphatase-like
2 2 SCOP 52822 Cell cycle control phosphatase, catalytic domain
2 2 SCOP 52862 Glutathione S-transferase (GST), N-terminal domain
2 2 SCOP 53099 Ribonuclease H
2 2 SCOP 53118 DnaQ-like 3'-5' exonuclease
2 2 SCOP 53351 Arginine methyltransferase
2 2 SCOP 53660 Dimeric isocitrate & isopropylmalate dehydrogenases
2 2 SCOP 53687 Tryptophan synthase beta subunit-like PLP-dependent enzymes
2 2 SCOP 53733 Aconitase iron-sulfur domain
2 2 SCOP 53796 PEP carboxykinase C-terminal domain
2 2 SCOP 53823 L-arabinose binding protein-like
2 1 SCOP 53888 Transferrin
2 2 SCOP 53902 Thiolase-related
2 2 SCOP 54044 Transglutaminase core
2 2 SCOP 54920 Nucleoside diphosphate kinase, NDK
2 2 SCOP 55748 N-myristoyl transferase, NMT
2 2 SCOP 55762 Cofilin-like
2 2 SCOP 55879 DNA gyrase/MutL, N-terminal domain
2 2 SCOP 55983 DNA polymerase processivity factor
2 2 SCOP 56004 Molybdenum cofactor-binding domain
2 2 SCOP 56108 Phosphatidylinositol phosphate kinase IIbeta, PIPK IIbeta
2 2 SCOP 56646 Medium chain acyl-CoA dehydrogenase, NM (N-terminal and middle) domains
2 2 SCOP 56816 Sec1/munc18-like (SM) proteins
2 2 SCOP 57799 Casein kinase II beta subunit
2 2 SCOP 57851 RING finger domain, C3HC4
2 2 SCOP 57925 Inhibitor of apoptosis (IAP) repeat
2 2 SCOP 63826 YWTD domain
2 2 SCOP 63888 P-domain of calnexin/calreticulin
2 2 SCOP 64089 BadF/BadG/BcrA/BcrD-like
2 2 SCOP 64198 AICAR transformylase domain of bifunctional purine biosynthesis enzyme ATIC
2 2 SCOP 64485 RNA-polymerase beta
2 2 SCOP 64490 RNA-polymerase beta-prime
2 2 SCOP 69236 Calnexin/calreticulin
2 2 SCOP 74693 Dachshund-homology domain
2 2 SCOP 74925 Cap-Gly domain
2 2 SCOP 75633 Cullin homology domain
2 2 SCOP 81605 PP2C-like
2 2 SCOP 81656 Meta-cation ATPase, catalytic domain P
2 2 SCOP 81659 Metal cation-transporting ATPase, ATP-binding domain N
2 2 SCOP 81838 BEACH domain
2 2 SCOP 81966 Cytoplasmic domain of inward rectifier potassium channel
2 2 SCOP 82110 MIR domain
2 2 SCOP 82172 DPP6 N-terminal domain-like
2 1 SCOP 82424 Choline/Carnitine O-acyltransferase
2 2 SCOP 88656 alpha-mannosidase, C-terminal domain
2 2 SCOP 88714 alpha-mannosidase
2 2 SCOP 89494 HMGL-like
2 1 SCOP 89572 Biotin dependent carboxylase carboxyltransferase domain
2 2 SCOP 89763 Ubiquitin activating enzymes (UBA)
2 2 SCOP 101153 Mob1/phocein
2 2 SCOP 101913 Sema domain
2 2 SCOP 102492 CAF1-like ribonuclease
2 2 SCOP 102755 Hsp90 middle domain
2 2 SCOP 140819 B56-like
2 2 SCOP 140991 FtsH protease domain-like
2 2 SCOP 141154 SPRY domain
2 2 SCOP 142922 WGR domain
2 2 SCOP 143812 GatB/GatE catalytic domain-like
2 1 SCOP 144031 Nq06-like
2 2 SCOP 159623 Fumble-like
1 1 SCOP 46549 Fumarate reductase/Succinate dehydogenase iron-sulfur protein, C-terminal domain
1 1 SCOP 46610 Fe,Mn superoxide dismutase (SOD), N-terminal domain
1 1 SCOP 46627 monodomain cytochrome c
1 1 SCOP 46847 Cell cycle transcription factor e2f-dp
1 1 SCOP 46859 ets domain
1 1 SCOP 46959 DNA repair factor XPA DNA- and RPA-binding domain, C-terminal subdomain
1 1 SCOP 47134 TBP-associated factors, TAFs
1 1 SCOP 47158 Mitochondrial import receptor subunit Tom20
1 1 SCOP 47566 Insect pheromone/odorant-binding proteins
1 1 SCOP 47588 Domain of poly(ADP-ribose) polymerase
1 1 SCOP 47662 t-snare proteins
1 1 SCOP 47742 CO dehydrogenase ISP C-domain like
1 1 SCOP 47763 PAH2 domain
1 1 SCOP 47875 Annexin
1 1 SCOP 47896 Transducin (alpha subunit), insertion domain
1 1 SCOP 47965 Transcription factor IIB (TFIIB), core domain
1 1 SCOP 48035 Guanido kinase N-terminal domain
1 1 SCOP 48141 Ribosomal protein L19 (L19e)
1 1 SCOP 48246 Protein prenyltransferases
1 1 SCOP 48251 Complement components
1 1 SCOP 48257 Citrate synthase
1 1 SCOP 48360 p120GAP domain-like
1 1 SCOP 48367 Ras GEF
1 1 SCOP 48399 Phoshoinositide 3-kinase (PI3K) helical domain
1 1 SCOP 48440 Protein prenylyltransferase
1 1 SCOP 48468 VHS domain
1 1 SCOP 48577 Isoprenyl diphosphate synthases
1 1 SCOP 49349 Alpha-adaptin ear subdomain-like
1 1 SCOP 49448 Second domain of Mu2 adaptin subunit (ap50) of ap2 adaptor
1 1 SCOP 49600 MATH domain
1 1 SCOP 49759 Calpain large subunit, middle domain (domain III)
1 1 SCOP 49778 Phosphatidylethanolamine binding protein
1 1 SCOP 49800 Ephrin receptor ligand binding domain
1 1 SCOP 49885 FHA domain
1 1 SCOP 50045 SH3-domain
1 1 SCOP 50114 C-terminal domain of ribosomal protein L2
1 1 SCOP 50183 Sm motif of small nuclear ribonucleoproteins, SNRNP
1 1 SCOP 50277 Myf domain
1 1 SCOP 50325 Inorganic pyrophosphatase
1 1 SCOP 50371 Ricin B-like
1 1 SCOP 50438 NADPH-cytochrome p450 reductase FAD-binding domain-like
1 1 SCOP 50466 EF-Tu/eEF-1alpha/eIF2-gamma C-terminal domain
1 1 SCOP 50476 PNP-oxidase like
1 1 SCOP 50616 N-terminal domain of alpha and beta subunits of F1 ATP synthase
1 1 SCOP 50776 Third domain of FERM
1 1 SCOP 50986 Regulator of chromosome condensation RCC1
1 1 SCOP 51012 alpha-Amylases, C-terminal beta-sheet domain
1 1 SCOP 51194 Homogentisate dioxygenase
1 1 SCOP 51231 Biotinyl/lipoyl-carrier proteins and domains
1 1 SCOP 51284 dUTPase-like
1 1 SCOP 51375 Decarboxylase
1 1 SCOP 51413 Inosine monophosphate dehydrogenase (IMPDH)
1 1 SCOP 51550 beta-N-acetylhexosaminidase catalytic domain
1 1 SCOP 51557 Adenosine/AMP deaminase
1 1 SCOP 51570 Class I aldolase
1 1 SCOP 51594 5-aminolaevulinate dehydratase, ALAD (porphobilinogen synthase)
1 1 SCOP 51605 Enolase
1 1 SCOP 51691 NadC C-terminal domain-like
1 1 SCOP 51696 Mammalian PLC
1 1 SCOP 51714 tRNA-guanine transglycosylase
1 1 SCOP 51868 6-phosphogluconate dehydrogenase-like, N-terminal domain
1 1 SCOP 51900 CoA-binding domain
1 1 SCOP 51906 C-terminal domain of adrenodoxin reductase-like
1 1 SCOP 51913 FAD-linked reductases, N-terminal domain
1 1 SCOP 52017 LeuD-like
1 1 SCOP 52030 GroEL-like chaperone, apical domain
1 1 SCOP 52052 Rna1p (RanGAP1), N-terminal domain
1 1 SCOP 52068 U2A'-like
1 1 SCOP 52088 CRAL/TRIO domain
1 1 SCOP 52103 Crotonase-like
1 1 SCOP 52167 Ribosomal protein L4
1 1 SCOP 52273 Acetylhydrolase
1 1 SCOP 52300 S-adenosylhomocystein hydrolase
1 1 SCOP 52331 Aspartyl dipeptidase PepE
1 1 SCOP 52397 Adenylyltransferase
1 1 SCOP 52403 N-type ATP pyrophosphatases
1 1 SCOP 52441 BC N-terminal domain-like
1 1 SCOP 52468 Deoxyhypusine synthase, DHS
1 1 SCOP 52589 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase, kinase domain
1 1 SCOP 52789 Low-molecular-weight phosphotyrosine protein phosphatases
1 1 SCOP 52895 spliceosomal protein U5-15Kd
1 1 SCOP 52973 ITPase (Ham1)
1 1 SCOP 53089 Glycerol kinase
1 1 SCOP 53143 ERF1/Dom34 middle domain-like
1 1 SCOP 53201 Leucine aminopeptidase, C-terminal domain
1 1 SCOP 53219 MogA-like
1 1 SCOP 53224 Aminoacid dehydrogenases
1 1 SCOP 53240 Malic enzyme N-domain
1 1 SCOP 53255 Cofactor-dependent phosphoglycerate mutase
1 1 SCOP 53258 Histidine acid phosphatase
1 1 SCOP 53267 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase, phosphatase domain
1 1 SCOP 53301 Integrin A (or I) domain
1 1 SCOP 53329 Formyltransferase
1 1 SCOP 53342 Fibrillarin homologue
1 1 SCOP 53354 Protein-L-isoaspartyl O-methyltransferase
1 1 SCOP 53452 beta 1,4 galactosyltransferase (b4GalT1)
1 1 SCOP 53461 UDP-glucose pyrophosphorylase
1 1 SCOP 53467 1,3-glucuronyltransferase
1 1 SCOP 53496 Prolyl oligopeptidase, C-terminal domain
1 1 SCOP 53525 Epoxide hydrolase
1 1 SCOP 53672 Aspartate/ornithine carbamoyltransferase
1 1 SCOP 53701 Phosphoglucose isomerase, PGI
1 1 SCOP 53749 Phosphoglycerate kinase
1 1 SCOP 53775 Glutaminase/Asparaginase
1 1 SCOP 54040 Calpain large subunit, catalytic domain (domain II)
1 1 SCOP 54054 Adenain-like
1 1 SCOP 54165 Chromo domain
1 1 SCOP 54193 L15e
1 1 SCOP 54198 HIT (HINT, histidine triad) family of protein kinase-interacting proteins
1 1 SCOP 54229 Ribonuclease PH domain 1-like
1 1 SCOP 54232 GHMP Kinase, N-terminal domain
1 1 SCOP 54293 2Fe-2S ferredoxin-related
1 1 SCOP 54312 2Fe-2S ferredoxin domains from multidomain proteins
1 1 SCOP 54399 GDI-like
1 1 SCOP 54535 FKBP immunophilin/proline isomerase
1 1 SCOP 54586 Cdc48 domain 2-like
1 1 SCOP 54594 Glyoxalase I (lactoylglutathione lyase)
1 1 SCOP 54687 Ribosomal protein L10e
1 1 SCOP 54701 Tetramerization domain of potassium channels
1 1 SCOP 54720 Fe,Mn superoxide dismutase (SOD), C-terminal domain
1 1 SCOP 54792 Eukaryotic type KH-domain (KH-domain type I)
1 1 SCOP 54815 Prokaryotic type KH domain (KH-domain type II)
1 1 SCOP 54827 Enolase N-terminal domain-like
1 1 SCOP 54981 EF-G/eEF-2 domains III and V
1 1 SCOP 55004 Poly(A) polymerase, PAP, C-terminal domain
1 1 SCOP 55036 NAD-binding domain of HMG-CoA reductase
1 1 SCOP 55069 Peptide methionine sulfoxide reductase
1 1 SCOP 55283 Ribosomal protein L5
1 1 SCOP 55288 RPB5
1 1 SCOP 55294 RPB6
1 1 SCOP 55299 YjgF/L-PSP
1 1 SCOP 55316 L30e/L7ae ribosomal proteins
1 1 SCOP 55323 ERF1/Dom34 C-terminal domain-like
1 1 SCOP 55348 GAPDH-like
1 1 SCOP 55368 Dihydrodipicolinate reductase-like
1 1 SCOP 55376 Glucose 6-phosphate dehydrogenase-like
1 1 SCOP 55419 Translation initiation factor eIF4e
1 1 SCOP 55456 SRF-like
1 1 SCOP 55482 N-terminal domain of eukaryotic peptide chain release factor subunit 1, ERF1
1 1 SCOP 55638 Cell cycle regulatory proteins
1 1 SCOP 55712 Clathrin adaptor appendage, alpha and beta chain-specific domain
1 1 SCOP 55771 Profilin (actin-binding protein)
1 1 SCOP 55798 PR-1-like
1 1 SCOP 55812 MutT-like
1 1 SCOP 55817 5'-nucleotidase (syn. UDP-sugar hydrolase), C-terminal domain
1 1 SCOP 55832 Thymidylate synthase/dCMP hydroxymethylase
1 1 SCOP 55847 N-acetylmuramoyl-L-alanine amidase-like
1 1 SCOP 55875 Heat shock protein 90, HSP90, N-terminal domain
1 1 SCOP 55896 Ribonuclease Rh-like
1 1 SCOP 55910 Ribosome anti-association factor eIF6 (aIF6)
1 1 SCOP 55921 Creatinase/aminopeptidase
1 1 SCOP 55935 Guanido kinase catalytic domain
1 1 SCOP 55946 TATA-box binding protein (TBP), C-terminal domain
1 1 SCOP 56020 The spindle assembly checkpoint protein mad2
1 1 SCOP 56043 PurM C-terminal domain-like
1 1 SCOP 56054 Ribosomal protein L6
1 1 SCOP 56088 Eukaryotic glutathione synthetase ATP-binding domain
1 1 SCOP 56220 DNase I-like
1 1 SCOP 56261 (Glycosyl)asparaginase
1 1 SCOP 56277 S-adenosylmethionine decarboxylase
1 1 SCOP 56288 Glyoxalase II (hydroxyacylglutathione hydrolase)
1 1 SCOP 56318 Nitrilase
1 1 SCOP 56361 Eukaryotic DNA topoisomerase I, catalytic core
1 1 SCOP 56367 SMAD MH1 domain
1 1 SCOP 56426 Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain
1 1 SCOP 56497 Fibrinogen C-terminal domain-like
1 1 SCOP 56525 Oxidoreductase molybdopterin-binding domain
1 1 SCOP 56535 Aromatic aminoacid monoxygenases, catalytic and oligomerization domains
1 1 SCOP 56543 Substrate-binding domain of HMG-CoA reductase
1 1 SCOP 56554 Insert subdomain of RNA polymerase alpha subunit
1 1 SCOP 56635 Heme-dependent catalases
1 1 SCOP 56720 Type II DNA topoisomerase
1 1 SCOP 56753 D-aminoacid aminotransferase-like PLP-dependent enzymes
1 1 SCOP 57507 Transforming growth factor (TGF)-beta
1 1 SCOP 57864 Pyk2-associated protein beta ARF-GAP domain
1 1 SCOP 57911 PHD domain
1 1 SCOP 57934 TAZ domain
1 1 SCOP 57998 Tropomyosin
1 1 SCOP 58039 SNARE fusion complex
1 1 SCOP 63381 Ferredoxin reductase FAD-binding domain-like
1 1 SCOP 63502 Frizzled cysteine-rich domain
1 1 SCOP 63571 PABC (PABP) domain
1 1 SCOP 63611 Pumilio repeat
1 1 SCOP 63873 Translationally controlled tumor protein TCTP (histamine-releasing factor)
1 1 SCOP 63971 Inosicase
1 1 SCOP 63984 Sir2 family of transcriptional regulators
1 1 SCOP 64006 Undecaprenyl diphosphate synthase
1 1 SCOP 64136 N-acetylglucosaminyltransferase I
1 1 SCOP 64154 YjeF N-terminal domain-like
1 1 SCOP 64388 Phoshatidylinositol transfer protein, PITP
1 1 SCOP 64599 Arfaptin, Rac-binding fragment
1 1 SCOP 68924 PEP carboxykinase N-terminal domain
1 1 SCOP 69013 alpha-ketoacid dehydrogenase kinase, N-terminal domain
1 1 SCOP 69198 SIAH, seven in absentia homolog
1 1 SCOP 69204 Nucleoplasmin-like core domain
1 1 SCOP 69210 APC10-like
1 1 SCOP 69319 Integrin alpha N-terminal domain
1 1 SCOP 69337 Alpha subunit of glutamate synthase, C-terminal domain
1 1 SCOP 69341 C-terminal domain of adenylylcyclase associated protein
1 1 SCOP 69501 DTD-like
1 1 SCOP 69557 Spermidine synthase
1 1 SCOP 69573 Molybdenum cofactor biosynthesis protein MoeB
1 1 SCOP 69619 HemD-like
1 1 SCOP 69646 Arp2/3 complex subunits
1 1 SCOP 69804 alpha-ketoacid dehydrogenase kinase, C-terminal domain
1 1 SCOP 69865 Argininosuccinate synthetase, C-terminal domain
1 1 SCOP 74679 SCF ubiquitin ligase complex WHB domain
1 1 SCOP 74714 acyl-CoA oxidase C-terminal domains
1 1 SCOP 74785 Translin
1 1 SCOP 74911 Aldose 1-epimerase (mutarotase)
1 1 SCOP 75073 Hydantoinase (dihydropyrimidinase), catalytic domain
1 1 SCOP 75079 Renal dipeptidase
1 1 SCOP 75305 Amidase signature (AS) enzymes
1 1 SCOP 75362 BM-002-like
1 1 SCOP 75383 UEV domain
1 1 SCOP 75434 Divalent ion tolerance proteins CutA (CutA1)
1 1 SCOP 75521 Clathrin coat assembly domain
1 1 SCOP 75621 Release factor
1 1 SCOP 81279 NF-kappa-B/REL/DORSAL transcription factors, C-terminal domain
1 1 SCOP 81286 Molybdenum-containing oxidoreductases-like dimerisation domain
1 1 SCOP 81288 RhoGDI-like
1 1 SCOP 81291 Arrestin/Vps26-like
1 1 SCOP 81315 Rel/Dorsal transcription factors, DNA-binding domain
1 1 SCOP 81318 RUNT domain
1 1 SCOP 81320 Rhodopsin-like
1 1 SCOP 81380 Skp1 dimerisation domain-like
1 1 SCOP 81405 Mitochondrial cytochrome c oxidase subunit IV
1 1 SCOP 81523 14 kDa protein of cytochrome bc1 complex (Ubiquinol-cytochrome c reductase)
1 1 SCOP 81589 Poly(A) polymerase, PAP, N-terminal domain
1 1 SCOP 81630 Poly(A) polymerase, PAP, middle domain
1 1 SCOP 81892 Poly A polymerase C-terminal region-like
1 1 SCOP 82200 Histone lysine methyltransferases
1 1 SCOP 82253 alpha-D-glucuronidase/Hyaluronidase catalytic domain
1 1 SCOP 82261 N-acetylglucosamine-6-phosphate deacetylase, NagA, catalytic domain
1 1 SCOP 82267 TatD Mg-dependent DNase-like
1 1 SCOP 82388 Predicted hydrolases Cof
1 1 SCOP 82458 Trunk domain of Sec23/24
1 1 SCOP 82515 PfkB-like kinase
1 1 SCOP 82540 Trehalose-6-phosphate synthase, OtsA
1 1 SCOP 82545 GckA/TtuD-like
1 1 SCOP 82583 G domain-linked domain
1 1 SCOP 82611 SMAD4-binding domain of oncoprotein Ski
1 1 SCOP 82636 MaoC-like
1 1 SCOP 82661 Poly A polymerase head domain-like
1 1 SCOP 82709 R3H domain
1 1 SCOP 82767 Sedlin (SEDL)
1 1 SCOP 88698 PUA domain
1 1 SCOP 88741 Branched-chain alpha-keto acid dehydrogenase Pyr module
1 1 SCOP 88784 rRNA adenine dimethylase-like
1 1 SCOP 88799 N-terminal, heterodimerisation domain of RBP7 (RpoE)
1 1 SCOP 89125 Nop domain
1 1 SCOP 89734 L-sulfolactate dehydrogenase-like
1 1 SCOP 90084 Glutaminase
1 1 SCOP 90097 Capz alpha-1 subunit
1 1 SCOP 90100 Capz beta-1 subunit
1 1 SCOP 101279 N-terminal domain of adenylylcyclase associated protein, CAP
1 1 SCOP 101392 Hsp90 co-chaperone CDC37
1 1 SCOP 101448 Formin homology 2 domain (FH2 domain)
1 1 SCOP 101536 Coatomer appendage domain
1 1 SCOP 101547 ASF1-like
1 1 SCOP 101691 PAZ domain
1 1 SCOP 101856 SPOC domain
1 1 SCOP 101899 NHL repeat
1 1 SCOP 102079 Putative alpha-L-fucosidase, catalytic domain
1 1 SCOP 102575 NOL1/NOP2/sun
1 1 SCOP 102887 Coproporphyrinogen III oxidase
1 1 SCOP 102928 NifU/IscU domain
1 1 SCOP 103244 Kinase associated domain 1, KA1
1 1 SCOP 103366 Hypothetical protein PH1602
1 1 SCOP 103492 Preprotein translocase SecY subunit
1 1 SCOP 103658 BAR domain
1 1 SCOP 109671 PCI domain (PINT motif)
1 1 SCOP 109686 DNA replication factor Cdt1
1 1 SCOP 109906 Surp module (SWAP domain)
1 1 SCOP 109994 VPS9 domain
1 1 SCOP 110080 DNA-binding protein LAG-1 (CSL)
1 1 SCOP 110218 DNA-binding protein LAG-1 (CSL)
1 1 SCOP 110272 TFIIH domain
1 1 SCOP 110509 NLI interacting factor-like phosphatase
1 1 SCOP 110773 Ubiquitin thiolesterase protein OTUB2 (Otubain-2)
1 1 SCOP 110858 Gamma-glutamyl cyclotransferase-like
1 1 SCOP 111233 YfcE-like
1 1 SCOP 111322 AF1104-like
1 1 SCOP 116891 CUT domain
1 1 SCOP 117002 Exportin HEAT-like repeat
1 1 SCOP 117685 AD-003 protein-like
1 1 SCOP 117714 Hypothetical esterase YJL068C
1 1 SCOP 117833 C9orf74 homolog
1 1 SCOP 117840 WWE domain
1 1 SCOP 117893 Band 7/SPFH domain
1 1 SCOP 118076 TRAPP components
1 1 SCOP 118216 Proton glutamate symport protein
1 1 SCOP 118285 Putative zinc binding domain
1 1 SCOP 140103 ISY1 N-terminal domain-like
1 1 SCOP 140769 MioX-like
1 1 SCOP 140833 Plakophilin 1 helical region
1 1 SCOP 141073 CalX-beta domain
1 1 SCOP 141113 Extended PAW domain
1 1 SCOP 141615 Cysteine dioxygenase type I
1 1 SCOP 142183 Pyrimidine 5'-nucleotidase (UMPH-1)
1 1 SCOP 142411 Selenoprotein W-related
1 1 SCOP 142532 Glutaminyl-peptide cyclotransferase-like
1 1 SCOP 142644 RPA4359-like
1 1 SCOP 142651 Methyltransferase 10 domain
1 1 SCOP 142878 Eukaryotic EndoU ribonuclease
1 1 SCOP 143001 TIM44-like
1 1 SCOP 143091 PTD012-like
1 1 SCOP 143114 NAP-like
1 1 SCOP 143725 Janus/Ocnus
1 1 SCOP 143777 mRNA decapping enzyme-like
1 1 SCOP 143876 ERH-like
1 1 SCOP 143906 Gamma-glutamyltranspeptidase-like
1 1 SCOP 143927 beta-CASP RNA-metabolising hydrolases
1 1 SCOP 143959 Sulfatase-modifying factor-like
1 1 SCOP 144028 Nqo4-like
1 1 SCOP 158640 Emsy N terminal (ENT) domain-like
1 1 SCOP 158703 Sec63 N-terminal domain
1 1 SCOP 158742 Trehalase-like
1 1 SCOP 158782 HAT/Suf repeat
1 1 SCOP 158886 AMPK-beta glycogen binding domain-like
1 1 SCOP 158893 Sec63 C-terminal domain-like
1 1 SCOP 159043 Plus3
1 1 SCOP 159513 EMG1/NEP1-like
1 1 SCOP 161071 SNF-like

The following families have one or more weak hits: