SUPERFAMILY is a database of structural and functional annotation for all proteins and genomes.

The SUPERFAMILY annotation is based on a collection of hidden Markov models, which represent structural protein domains at the SCOP superfamily level. A superfamily groups together domains which have an evolutionary relationship. The annotation is produced by scanning protein sequences from over 3,200 completely sequenced genomes against the hidden Markov models

SUPERFAMILY 1.75 can be accessed from

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Quick Sequence Search

Paste a protein sequence in FASTA format, or visit the full search page for more options

Keyword Search

Search for superfamily, family or species names plus sequence, SCOP, PDB or hidden Markov model IDs.

SCOP Hierarchy

Browse the SCOP hierarchy

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Taxonomic Hierarchy

Browse a tree of all the SUPERFAMILY genomes

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Genome Statistics

View a variety of statistics on the structural assignment of 3,200 genomes

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