ENSMGAP00000005623 from Meleagris gallopavo 76

For a sequence (see Protein sequence) in target, dcGO predictor has the following procedures to predict the ontology terms of the target:

First, obtain Domain architecture and its residual domains and supra-domains from the SUPERFAMILY database.

Then, use the domain-centric annotations to predict the ontology terms of the target:

If a target contained a domain/supra-domain, then all ontology terms associated to that domain/supra-domain are transferred to the target (together with hypergeometric score, h-score);
When a target-to-term transfer is supported by one or more residential domains/supra-domains, sum up h-scores to calculate predictive score (p-score);
The p-score is then rescaled to the range of 0-1. For each namespace (e.g., three sub-ontologies for GO), p-score=(SUM-MIN)/(MAX-MIN), where SUM is the sum of all h-scores to support a term transferred to the target, MIN and MAX are respectively the minimum and maximum of SUM over a whole list of predicted terms for the target;

Finally, the predictive score being rescaled is used to rank the predictions. The higher value of the p-score indicates the more evident the prediction is. In the dcGO, each ontology has a slim version on its own, containing ontological terms at four levels of increasing granularity (that is, being highly general, general, specific, and highly specific). Listed in the table are the top 5 predictions for each specificity and for each namespace. In addition to those restricted by the term specificity, i.e., Export prediction (slim version), the full list of predictions are also provided for the download, i.e., Export prediction (full version).

QRIFVYVTWTPSEEGKVRELVTFVVNGIVKHQAVLLGVAEQPVKKKKSLWDTIKKKNSSE TSIPRKINKRNSKVKNVNKTFQVSQEADRLRSPLQSCENQNAMQNSTSPVNESPVGSENK LPISPIAPVLEELRTTACTPLSMRRSTTFSDIAAAVNEGLLPVMDSHNFNKSVDDHSELK SGSAYSCSGLGKPPISNDEVILNCTLSPVCTPEHSSSVPFLSTRRFLSPDSFVNDNYQVD GDIVVPSVPILSPDQFVKDMQLYMQSKTPKPEAALISSTTETYVVKECVPSKQKENGDRW TKTQVHVEHVLNEAFEVRCVDSQVPHHNKSKENHFTCPPIGEFQTRSSQIEQPKKRPVLS ATVIKNKPNADERKKMEMLQPKSKKCLNSAIMTCENMVPLYTKAEISERLPVIGPVSAGN KCPSDKVSSSTESTSLCRKRKNEVSVEKNRVVGPVHVEEVERKRALTSSMDNKTQATVRP SAFKHTTRERIGQNKKAGSSLQKASKTNSRINKPIAGLAQSHLTFVKPLKTVIPRHPMPF AAQNMFYDERWKEKQQRGFTWWLNFVLTPDDFSVKTNTSQVNAAALILGEENHHKTSVPK APTKEEASLKAYTARRRLNKLRRDACRLFTSETMVKAIKKLEVEIETRRLLVRRDRHLWK DVGERQKVLNWLLSYNPLWLRIGLETVYGELITLESNSDFMGLAIFILNRLLWNPDIAAE YRHPTVPHLYREGHEEALSKFTLKKLLLLVCFLDRAKQSRLIGHDPCLFCKDAEFKTSKD ILLAISRDFLSGEGDLSRHLGFLGLPVSHIQTPLDEFDFAVTNLAVDLQCGIRLVRAMEL LTRDWNLSKQLRVPAISRLQKMHNVDIVLSVLKKRGIHLKDDSGASIDCRDIVDRHRERT LALLWKIVFAFQVDILLNVEQLKEEIQFLKNAHKIKMQLGALKLFSSCCRIQEDNSSSPS PQSHGENVKLLMAWVNAVCGFYNIKVENFTVCFSDGRVLCHLIHHYHPCYVPLEAVCQRT TQTVECSRTHKVGLNCSSSSESDTSLNVMEGPFDQTVTASVLYKELLENEKKNFQLINNA VSDLGGIPAMIHYSDMSNTIPDEKVVITYLSFLCSRLLDLRQETRAARLIQSAWRKFRLK RELKLSQERDRAARIIQKYAINFLSHRRLVKKHNAAVIIQKHWRRHLARIIFLNLKKTKW EEARSKSATVIQAYWRRYSARKSYLQLRYYVIFVQARIRMLLAVAAYKRILWATVTIQNR LRASNLAKEHRKRYEILRSSALTIQSAFRKWRKHKIQEKIRAAVVLQRYFRKWQSSKLTK RKRAALLVQSWYRMHRDMKRYLRIKQSIIKIQAWYRCQIARRIYQEYRAQIVMIQQHYRA YKLGKNEREIYLQKRAAVVVLQAAFRGKKARILYRQTKAACVVQSLWRMRQARQRFLLIK KSVTLLQSHVRKHQQVKRYKEMKNAASVIQAWFRAHVTSKKAALSFQRMRLAAIVLQSAY RGRKARKEAHILRSVIKIQSSFRAYVIRKRFEDLRNATVKIQACVKMRQARRYYRALREA TLYVQRRYRSRRYALQLKEDYRKLKGACIRIQAAVRGCLVRKQIKRWRETAVFLQAQYRM RRTRARYLLMYSAAVVIQKHYRAYHKQLCQRQEFLQAKKAAVCIQAGYRGYKARKKLKLE HRSAVKIQAAFRAHATRKKYQAMIQASVVIQRWYRTCKTSNRQRLTFLKTRAAVLTLQAA FRGYQVRKQIRRQCAAATAIQSAFRKFMALKTFRLMNHAVLNIQRRYRAIVISRKQRQEY VELRNCVVRLQAIWRGKAARKKIQKMHNLATIIQSYYRMHVNQLKFKKLRRSTLVIQRYF RAYCMKKNQRARYLKTKAAVLVLQSAYRGMTVRKQLRELSKAATTIQAAFKSYLVKKDYV GLRSAAVVIQRRYRAVIHTKWQRQKYLSLKAAAIKMQAIYRGVKVRRQIHSMHRAAIRIQ AMFKMHRINIRYQAIRMAAIIIQRQYRAFCLGRVQRKKYLELKKSSIVLQAAFRGMKVRQ DLKMMHQSAALIQSYYRVHKQQRDFRNLLLATRRIQQWYRACKERNRQVHNYMTVRSATL CLQAAFRGMKARRLLRTMNHSAELIQRRFRTFLQRKRFISLRTAAVVIQRKYRATKLAKI QRQQYLSLLNAAVIIQSAYRGFLARQKMRQMHQAATVIQATLRMRKIYISYQVLRLASVI IQQRYRAYREGKRVRKMYLKTYKSVLVIQAAYRGMKTRCFLKKRHEAALIIQRNYRMYRQ YHRYRRVQWATQLIQRKFRANSLRNIAVQRYFSFKKAAICIQRAFRDMRLKKQHQEMHRA ATVVQKNYKAFREHQRYLSLKAAALVFQRRYRALILSRQHTQEYLYLRRATIRLQAVYRG IRVRKSIEHMHLAARTIQSAYKMHRNRSAYQKMRTAAVVIQNYYRSYVKAKNQQKKYLTI KKSALLIQASYRGMKERQQLKMMRASAIIIQSSYRMYIQHKYYKQLCWAVRVIQQRFRAK IAKKADMENYAKIRKAIICLQSSFRAKKARQLRKTNAAALCIQSFLRMRVERKRFLVKKA AAITIQSAFRCQRARARYKSVQNSIVAIQRWYRACHSARLQKAEYSLQRQAIIIIQSAYR GMKARKLTRQIRATRKIQSFLQMAVQRRKFIQLKRAAITLQACYLMHKAKSQYASYKKAA VVLQRWYRSHLIVKHQRMTYLQTQKKIILVQAVVRRFIVKKRFQKIKESAIKIQASYRGF KARRLANKVRAARVIQAWFRGCKARKEYASMVEAVRIIKSHFRTKRQRTWFLKMKFCALT IQRRWRATLAARMVRLQFLATKKKHEAACLIQTTYRCFKERRKLDRQKAAAVTIQKHLRA WQEGRLQFMKYNKIRRAVIKLQAFIRGYLVRKKFLEQKQKKRLLYFIAAAYHHVSAIKIQ RAYRMHLAYKLAENHISSVLIIQKWFRAKMQRRRFQRDLQRIVQCQRMIRGWLNRRNDAA TVIQRHVRRFLACRRKRKIAVGIIKFQALWRGYSWRKNNDTAKTKALRLSLEKANRKSKE ENKLCNRTSIAIEYLLKYKHISYILAALKHLEVVTRLSPLCCENMAQSRAIFTIFVLIRS CNRSVPCMDVIRYSVQVLLNVSKYERTTQAVYEVDNCIDTLLDLLQMYRGKAGDKISEKG GSIFTKTCCLLAILSKDSKRALEIRSMPRVVTCIQSLYKLTARKCKMDAERTLAKQKTST LISGISFIPVTPLRIKTVSRIKPDWVLRKDNMQEVVDPLQAIVMVMDTLGIAC

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ENSMGAP00000005623 (Meleagris gallopavo 76_2)

Protein sequence

Domain architecture