ENSMGAP00000014297 from Meleagris gallopavo 76

For a sequence (see Protein sequence) in target, dcGO predictor has the following procedures to predict the ontology terms of the target:

First, obtain Domain architecture and its residual domains and supra-domains from the SUPERFAMILY database.

Then, use the domain-centric annotations to predict the ontology terms of the target:

If a target contained a domain/supra-domain, then all ontology terms associated to that domain/supra-domain are transferred to the target (together with hypergeometric score, h-score);
When a target-to-term transfer is supported by one or more residential domains/supra-domains, sum up h-scores to calculate predictive score (p-score);
The p-score is then rescaled to the range of 0-1. For each namespace (e.g., three sub-ontologies for GO), p-score=(SUM-MIN)/(MAX-MIN), where SUM is the sum of all h-scores to support a term transferred to the target, MIN and MAX are respectively the minimum and maximum of SUM over a whole list of predicted terms for the target;

Finally, the predictive score being rescaled is used to rank the predictions. The higher value of the p-score indicates the more evident the prediction is. In the dcGO, each ontology has a slim version on its own, containing ontological terms at four levels of increasing granularity (that is, being highly general, general, specific, and highly specific). Listed in the table are the top 5 predictions for each specificity and for each namespace. In addition to those restricted by the term specificity, i.e., Export prediction (slim version), the full list of predictions are also provided for the download, i.e., Export prediction (full version).

GCFPQLPDKGGSYFLGTISHLSFKMQVQRECTQKKTFTTWINSILAKHTPPSVISDLYTD IQQGHMLLDLLEVLSGQHLPREKGCNTFQCRSNIENALTFLRSKSLKLINIHVADIIEGK PSIVLGLIWTIIFHFHIEELARTLACTYNQPSLECSSTVDSSPKARRSAKKSAKIKERWK ISATKALLFWAKEQCSLCGSISVNDFKSSWRSGLPFLAIINALRPGLIDLEKAKARSNKE NLDEAFRIAELELNIPRLLEPEDVDVMNPDEKSIMTYVAQFLQCSRNMPETEDMQGKVTE TVSWLAVQGKKLANLLMDTENETYYQKYKEMMSFMEAFNREKKAFLPLLSSKRSGAELSE GQQQMREEWSKLISQINEWKAQLDQMLPPPLDGIEAWLQKVEHLQAEDLPDLQDPFKAMS LFSEIISVFKGLMNCFDSHLETLQSFENKDENNMPLVVPEKLEEMKRRFNDIRFTNSSSL LEYHYGLCSAFANEVTLKLNIWDVKYGTKESVESLLENWNNFIKEKRLKTQLETAADICE DLKNKNISNLDLEISKLFKTVESKISMCKDYISNVNTTLQKVLSSWSSYTEKLYLLKTWL EEKQNEYPIEVPAEVLANWNSVHASLNEAGNYLIEVSKEQVGSNIAKELKKLNRKWAKFI KKTRFVSQLSISSFKTRGTENTQRYPIRKSLPLSISVGDELNENVNKLGEENTDTAEKAR ELPGGMEKIEELLGSVESWATETECLLSETGHKTPVEPQMEEYLQSLAAKGISYQEQVLA VEEILQSLMKNASSQVSQQHCHTTGLPARIKEARDRIEAVMGDMNNILPKSEKKPSQREA LLNFEESQKDIEVSISKAVELVSQKLSREVHISRYEEAFNALDNKVLDNFLKAVEQLKSI SSDQEKLAVEEKSEDIRKRWEAAHNEIISCVQLLLEREKKKFNTTFKKINKQLGKEKKLL NMNKTKGLIKEHEAFFSHEGSLKELSKSLEDLKILGKLAEETVPDLQTFAADSEQKLEKL QQTVADTYTALLSHLKFLLNHRSSIVASENGEKPSSTQQIDILSVQETSRPSEDMALETD MKHHNGESCEKMFEEGSDSPTPALLESYNTQRRNLEELLQVSRDKVASGFTDEIKGTSCL QNKLLELQMVENDINSGWAQLGNISSTLENLVDEVKQAAISETRGKLEGELKELQDIIST RTNSLRTALEIVLPIENESILLCELDQRLNKKGIQQFNLVNSDLAYGELKELQRSILNQI EVCKQLEHLDSSARDEFNPIDLQAASKIMFYYQNQLEEMSHKMQIRETVLKDLEAFMASL RKIKSSVKHLIDPLGKPEIQGKTRREAAQELSHMAKEAQCLDERLKTVDICLEDAECGRN TSCEKLLQTLSEELNVTGDHSSEQMLMEGNDLYRVFSTRNEELLKNIQDLRDRINKIGLK DPTVPAIQQRVKSLMELEKELDCSAVEMKSMREIANKLLQMEEEKAEESNEQCRVTERSW EDTKLLLAECQEQCTRALELLKQYQSCKSSLTSIIHKQEIVLSQQNSYMGKDNLNRLITK IEEAKEEFNDHAEDVDKINQICKNLQFQLNKMRSFEEPPFENEANIIVDRWLDINEKTEN YCDNLGRAQALWDKLLGLSGTIDAWANAELKNTEGRCLTDEDLTQLKACLSVQEQKLQKF DNTVAEIEELLNSNEPPLELQVIRSSIVQKMELIKDLLTAKRRTSELSVNTAELKGDLDL AKTQIGMTESLLKALSPSDTLEIFTKLEEIHQKILQQKHHVTLLQEETDCPDVDELNKQL KCVTDLFNKKKHVFQDHFIGVLNRQCKNFNDWFSSTQLSLKDCFDPSETKQMLEEKLQKL KHFFTSEGKDGDIQEVKTLLNKVKHYLPKASINQLSSRVRDQEAELQRLISKCQKREKEL GTSLQQLNSLQESNTVLEKWLTTQEEKLHEIKKDEIKLENLYKTLLMQREPFDSLAQLAN SLRETGLTEDEIISETSSLVSRYQTLMTNVNEMAGNTQGLAVDENFKELTQDMSNWIKKL EKAINNLSSQESELAPDERINQIKEIMALKDAGDAKIQNIVSVGEMLIRNDKIKKPEIQQ TVSDLQNQWERTCQLATAYRSPQEQLLFNREQYEQSKDDLRLALTELKKQHQEMDFALQP GLLEKQAQLASYTKLLQKAEDLTSQLNELESRDHVQSFAENPRFTEESWLELKHQHENLL SQLQAAVETLERHVQEHQQFQDMVTVLNTEIKTVSKKLADYVSPTVEQTSTEQKQLKSQE QEAPLCQFEDMLKKILVLAETVKQNTSSPGQKFIEDEIETLQSEHRSLEEKLENVKQKKE NIFSEALELKDDLTDGVQMENKLKREMQIISDTPVAAEEGTTTAELRECLEMPTKEGAAG VDQKELFPGVQVNTEYFEEEQKVNKLKNEVAELDIVLINEQLKELENLQTELETWKAKSL CLSQETFPDATRSNGAELQSPEPVVPCWDRLLQELDAVKAVKQQQSCLVNEYQKNLSAAQ SSMKNLATEKDNIKMGPMNNTVLLEKIKACVQSLHKERDVLNRLKTQQELLSQHLTCMDK VLTASKMRQLEQWWQHMEQAVQKKHDQVLAEINEFNTLMDKAQDIQRLIQEQYLQTESCS SAGEKAKCPIIWTAELQNIKHGLSLLKRKIELQMQRIWSDEEKIALESCIQDLQSKLEAL SEQHTPQDEVRVTGPAVKKQDIMKKLKENVSWVKDSLSSLDQKAALFPCDVKSQIRNCEL MRNEVLDREPVIEALGNELQHILPNLKPEEISDMTFLLQALQNSYKALVLKSVERLQHLQ LQLEERQRLTAEVEKVHCQLRNAEALGRPDMNQTSTCSELISQQDILKEILKDVQEIEGL ISSHCEESQITAGELSLSEQLFLIDQLRSLKNRARKTQRQIQSKCHEVGKKIAVYREFAE GITSLQKDLSDLQCSELKLEEELTGATQEVKNKCKALKEKVLSFQSNLSQIMKFKEIFEC IGLNWDSFQLDELHELQTQFFKIRNKIKGKITHFGNVIRECDKFHALLNEIRTMTSAVRK EANILSDRSNSSPAENLVSAQILLQTVQQILYLIQEVENQINKNEVFHTLFKESKRQEIK SLETDVEELNLFLQNLVSSLQCVNKEDIQNVAEHLSHAIRHVQLELQQPMVVDMKMMQYE KMRWESIQNMMSAEFSAIKCIMEKERGSQEEKSLAAGVETKLRALADHEIQLKTDIAARV SALEEACKAGELYTKAVERAAKFLEDCEAQVRSAAVELSSSEDAYQTPQWKQEEFDSAKA DIEQLYSKLKNLVKPEDKICLENTLRELINKSLALKGKIQRNEADKQSYLEKYKSYSKCK DKVCDDLNNLGKMLGQSLSQTPMSYKEALENLQECKILVSNIDSAEDDLVKLRQVSGELM RLCKGSDRALGRIVTALWENWLGLLEAAKELEINCEELKQEWKFINEELEREAIILDKLQ EEQPESLKEKEKATREELVELLDSVYAFEENISRQQLLLLLLLHRIRNILNTPENVEAET ALPALCEIKTMQDRCKKLFEKTQDRKNLIQSEIQERSKITEEINAVKNALQNALSVLSQD AVGKAAQLKEVQSVIDKESQNLKDIMEKLRIRYSEMYTIVPAETEAQLEDCKKTLQDLED KISFENLQSSPQYVLKGKAETINNGLQAIEKMLEQKTESVAKAKEVQKQIWDMLDLWHYK LNELDAEVHDIVEQDSCHAQELMDILMIPLQHYQQVSQLAERRTAILNKAANKMEEYDEL LKDMKVWIENTNSLLRAGAQNDSAKRLHKYTDGLQMALEDSEQKQNLLHSVYLELEELTP VFETDSIMQQLNEAEEEVATLQQEIAEILPQIQHVADELDAIESHVKMFEKDVMKMKTIL SSEDLLELSPKDQLKHGQVILDHIGPMQKTIVHIQSYEEDLQLPGVKKQPVSVFRRARQL LRELKKIEKITKEQNELLEEAVKKTEECEQEIEKLKQFLKNNLAEKSHEYQPHTQKTSCP EFQGEMEAIKEEIIKLCQRKEDILTGMKNSMSELHQRLQEEVPEPGDEPTASAFGDSIGT DVSDVQLKKRGLMSLLPCLDEESEDAFHSKQEKGSTVTEIDVSFWPSLKYKEKHKEDSAT SWSSGTLSDGGAQVMNSAVIHSINSWGGSKMKRDGVLSAPFASKGDESVTPPPVPNATQG PRGKEGDPEEAVDGGRPEPGTILQACKAQVAELEQWLDKTKVSLGSDPQTPKMQQMVELQ LGDFQVMLSEIEQKVLSLLEDGGNSAGHQQEAEDLSLKLKEVKCNLEKVQMMLQDKYSEE QIPNRERIDPESLKMLHSNGSSMPQLGLAEQPFLQQNGFQHPQDLKVKAAEQKSLIDFIE SCVEKMQPQFEDSVKSEPRYKATKSLPRFSNGESDPKSKKADPTLAPKDQTGNKWQYLQQ ELSSKMKSPLCQLVEPQITTKLNMLPRGVFPNAGASTVEELKTYTVQLGDLSQEANVVHA QENVAEEVSSNLDKKLFELLLAISRCLDNMEEMLNTSVLSTEEAAVQQVLYETLSVELQK LHADLSDKKDDLLKSITCAGGSTDVFCECFNNLQAWLEQTQAATASRSNSVKAGLDHNTS YQNETRLLYDQLTEKKATLQQCLNAIRGHNVSEQLQKTDACTLELQNFENQVAKLRGYGE RFQLPVTLIQEAYKLEDVLDDMWGILKAKYVELNSPSISESQYEDLLCGFAELVAIGQEK IAQDAKQLTKSRAALQSHLENHKDFFHNLMTHMAFMQAFSKKVNPSVLQKRENFWTGLVN EVKLLEQKASQYGIRLENLLKEWTEFDDECLAFNKELEALTSTLPSVNLVEETEERLMER IALLQQIKNNVDEKHARLYQMVKEGKKLLTAVSCPEITNQIGKLEEQWLSLTKKVGNELH KLQTLLKLLVSYNRDSEELRKWLDSAEQRMKFWKEQSLNVSQDLPTIRDNMDSLFTFSKE VDDKSSLKSSVVSTANQLFHVKQADTAGLRSSLAKFEQKWGELITQLPAIQEKLHQLQME KLSSREAIAELMTWLDHVEQQQGHEEPINAQSSVAQVRSLLQKYKEYVMEMNFKQWMVDF VNQSLLQMSTCDVESKRYERTEFAECLGEVNLRWHRLQASLNRKIQDLEHLLEDATENEN KAQTLCNWLEAQSDRMRSLQTPASLISAQNTLDDCKDLENQLAMKSKMLDELKQSMSLNG GTEQTPEVLSFRIADLCEMKDSVVSQVAQLKVSMQSILEQWKVYDDIYAEVSLLMTRYLY CIDQCKPSVPSLEALKNQVKTLQSLQDELENSEESWAKLQVAANNLKKNCSPSFAEIIDQ KCTEAHTRWSSVNEDITDQLRTAQATLQLWEPYDSLCTEAAAKLQQHEEQCTQLLDARMP EDNMIETLKQRIQDVKNLQNGLQNIVGCRSQISELADQIKQQAGTAAQAVLLEKLQPLQR ASYLEKMLQRKLDELEFNLLQLEDFKNCLETLEGHVKNCTDAFDSLHLEGETDNSELLMN HTLELAALSPSIESLNEASIKLPVSDFILKKMQSLTRQWSQKTATALEHCSVLEGTQTDE KKFLQKCENWMKFLEKMKEALKTDVPGRFEELQEQQRVYEMLQTEISINQQTFNSIIAKV LLFLESGEAEKRTEFISKLTLLKEQWQNVIWLVQQRKKDIDGLVSQWQLFRGSLQSLSRF LADTNSFLTAVKSQNCYSLYHLRNLIHDFKSKAVILQRWQGMYSSIIDVGEKLRTDSDPE TSAVLQEELSQLQQSWGDTQVQLEKMKTQLSSILQQSWDSCEKHTKELESRLRELKDEVK DPLPVEHEELYKSKEHIKELEQSLADWAHNMKELQAMKAELAHCILTEDMMVLQEQVEHL HRQWEELCLRVSLRKQEIEDRLNAWTVFNEKNKELCSWLVQMESKVLQTADVSIEDMIDK LQKDCMEEINLFSENKLHLKQMGDQLIKASNKSRVAEIDDKLNKINDRWQHLFDVIGARV KKLKETFAFIQLLDKNMSNLRTWLARIESELSKPVVYDICDDQEIQKRLAEQQDLQRDIE QHTAGVESVFNICEVLLHDSDACANETECDSIQQTSRSLDRRWRNICAMSMERRMKIEET WRLWQRFLDDYSRFEDWLKSAERTAASPNSSEVLYTHAKEELKKFEAFQRQIHERLTQLE LINKQYRRLARENRTDSASKLKQMVHEGNQRWDNLQKRVAAILRRLKHFTNRRDEFEATR ENILVWLTEMDLQLTNVEHFSKSNFDDKMRQLNGFQQEITLHTNKIDQLIVFGEQLIQKS EPLDAILIEDELEELHRYCQEVFGRVARFHQRLTSRHPGLDDEKETSENETDPEDSREIQ NDPWHKKAISEGPSSPQSLCHLMPPTQGHERSGCETPTPVSVDSIPLEWDHTGDVGGSSS HEDEEEATYYSALSGKTVSEAHPWHSPESPVCRKHRYNQAEIVGDVLSGPETSTPYKPGY VKQLSSASSSSVNKENITSANMSDEEPQDDQELVTITAAEKQSGIIDRWELIQAQDLRNK LRIKQHLQQWQQVNSDLSDVSAWLDKTEEELEELQKAKPPASMQAMEQRVKKLKDTLKAF DNYKAVVLSVNLSSKEFQKADSTEFKELQNRLRKVNLRWEKATHSLDNWRKGLRQALLHC QDFHDQSQKLILWLASAEGRRNEAQITDPNADPHTILESQKELMQLEKELLEQQLKVNCL QELSAYLLLKSDGEDYIEADEKVHVIGKKLKQLIEQVSHDLKSLQGSLDSRVFLPVPDDL DSEVYHPVAVKSSPPVKKMTIRRTSDGRKNSNTRAESHAQPTHVVPRSPSFFYRVLRAAL PLQLFFLLLLLLACMIPSSEEDYSCTQANNFARSFYPMLRYTNGPPPT

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ENSMGAP00000014297 (Meleagris gallopavo 76_2)

Protein sequence

Domain architecture