ENSBTAP00000018496 from Bos taurus 76

For a sequence (see Protein sequence) in target, dcGO predictor has the following procedures to predict the ontology terms of the target:

First, obtain Domain architecture and its residual domains and supra-domains from the SUPERFAMILY database.

Then, use the domain-centric annotations to predict the ontology terms of the target:

If a target contained a domain/supra-domain, then all ontology terms associated to that domain/supra-domain are transferred to the target (together with hypergeometric score, h-score);
When a target-to-term transfer is supported by one or more residential domains/supra-domains, sum up h-scores to calculate predictive score (p-score);
The p-score is then rescaled to the range of 0-1. For each namespace (e.g., three sub-ontologies for GO), p-score=(SUM-MIN)/(MAX-MIN), where SUM is the sum of all h-scores to support a term transferred to the target, MIN and MAX are respectively the minimum and maximum of SUM over a whole list of predicted terms for the target;

Finally, the predictive score being rescaled is used to rank the predictions. The higher value of the p-score indicates the more evident the prediction is. In the dcGO, each ontology has a slim version on its own, containing ontological terms at four levels of increasing granularity (that is, being highly general, general, specific, and highly specific). Listed in the table are the top 5 predictions for each specificity and for each namespace. In addition to those restricted by the term specificity, i.e., Export prediction (slim version), the full list of predictions are also provided for the download, i.e., Export prediction (full version).

MPSDSFCLAAQARLDSKWLKTDIQLAFTRDGLCGLWNEMVKDGEIVYTGTELSQNGELPP RKDDGVDTQIGTKKEDLNDKEKKEEEETPAPAYRAKSILESWVWGKQPDVNELKECLSVL VKEQQALAIQSATTTLSALRLKQRLIVLERYFIALNRTVFQENVKVKWKSSNISLPPVDK KSSRPAGKGVEGLARVGSRAALSFAFAFLRRAWRSGEDADLCSELLQESLDALRALPEAS LFDESTVSSVWLEVVERATRFLRSVVTGDVHGTPGTKGPGSIPLQDQHLALAILLELAVQ RGALSQMLSAVLLLLHLWDSGTRETDNERSAQGTSAPLLPLLRRFRSIVCSKDGPCAEVD THLLSGPLSPNESFLRYLTLPQDNELAIDLRQTAVVVMAHLDRLATPCMPPLCSSPTSHK GSLQEVIGWGLIGWKYYANVIGPIQCEGLANLGVTQIACAEKRFLILSRNGRVYTQAYNS DTLAPQLVQGLASRNIVKIAAHSDGHHYLALAATGEVYSWGCGDGGRLGHGDTVPLEEPK VISAFSGKQAGKHVVHIACGSTYSAAITAEGELYTWGRGNYGRLGHGSSEDEAIPMLVAG LKGLKVIDVACGSGDAQTLAVTENGQVWSWGDGDYGKLGRGGSDGCKTPKLIEKLQDLDV VKVRCGSQFSVALTKDGQVYSWGKGDNQRLGHGTEEHVRYPKLLEGLQGKKVIDVAAGST HCLALTEDSEVHSWGSNDQCQHFDTLRVTKPEPSALPGLDTKHIVGIACGPAQSFAWSSC SEWSIGLRVPFVVDICSMTFEQLDLLLRQVSEGMDGTADWPPPQEKECMTVATLNLLRLQ LHAAISHQVDPEFLGLGLGSVLLNSLKQTVVALASSAGVLSTVQAAAQAVLQSGWSVLLP TAEERARALSALLPCAVSGNEVNISPGRRFMIDLLVGSLMADGGLESALNAAITAEIQDI EAKKEAQKEKEIDEQEANASTFHRSRTPLDKDLINTGIYESSGKQCLPLVQLIQQLLRNI ASQTVARLKDVARRISSCLDFEQHSRERSASLDLLLRFQRLLISKLYPGESVGQTSEISS PELMGVGSLLKKYTALLCTHIGDILPVAASIASTSWRHFAEVACIVEGDFTGILLPELVV SIVLLLSKNAGLMQEAGAVPLLGGLLEHLDRFNHLAPGKERDDLEELAWPGIMVYTESFF TGQNCRNNEEVTLIRKADLENHNKDGGFWTVIDGKVYDIKDFQTQSLTGNSILAQFVGED PVVALEAALQFEDTRESMHAFCVGQYLEPDQEVVTIPDLGSLSSPLIDTERNLGLLLGLH ASYLAMSTPLSPVEVECAKWLQSSIFSGGLQTSQIHYSYNEEKDEDHCSSPGGTPASKSR LCSHRQALGDHAQAFLQAIADNNIQDHNVKDFLCQIERYCRQCHLTTPITFPPEHPVEEV GRLLLCCLLKHEDLGHVALSLVHAGTLGIEQVKHRTLPKSVVDVCRVVYQAKCSLIKTHQ EQGRSYKEVCAPVIERLRFLFNELRPAVCNDLSIMSKFKLLSSLPRWKRIAQKIIRERRK KRDIVPKKPESTEEEEKIGNGESDLEEACILPHSPINVDKRPITIKSPKDKWQPLLSTVT GVHRYKWLKQNVQGLYPQSALLSTIAEFALKEEPVDVEKMRKCLLKQLERAEVRLEGIDT ILKLAAKNFLLPSVQYAMFCGWQRLIPEGIDIGEPLTDCLKDVDLIPPFNRMLLEVTFGK LYTWAVQNIRNVLIDANTKFKELGIQPVPLQTITNENPSGPSLGTTPQARFLLVMLSMLT LQHGAHNLSLLLNSGTLALTQTALRLIGPSCDNVEEDMNASARGASATVLEETRKETAPV QLPVSGPELAAMMKIGTRVMRGVDWKWGDQDGPPPGLGRVIGELGEDGWIRVQWDTGSTN SYRMGKEGKYDLKLAELPVSTQPSAEDSDTEDDSEAEQIERNIHPTAMMLTSTVNLLQTL CLSAGVHAEVMQSEATKTLCGLLRMLVESGTTDKTSSPSRLVCREQHRSWCTLGFVRSIA LTPHMCAALSSPPWISLLVKVVEGHSPFTAASLQRQILAVHLLQAVLPSWDKTERARDME CLVEKLFGFLGSLLTTCSSDVPFLRESTLRRRRARPQASLTATHSSTLAEEVVALLRTLH SLGQWNGLINKYINSQLHSVTRSCAGKPAEGALLDDYFPDCENPEVGSLMAVLAVIGGID GRLRLGGQVMHDDFGEGTVTRITPKGKITVQFCDLRTCRVCPLNQLKPLPAVAFSVTNLP FTEPMLSVWAQLVNLAGSKLEKHKIKKSPKQGFAGQVDLDLLRCQQLKLYILKAGRALLS HQDQLRQILSQPAVQEAAAAHTDSDDGAAVSPDLVDMSPEGPQPPMILLQQLLASATQPS PVKAIFDKQELEAAALAVCQCLAVESTHPLSPVFEDCSSSEATTPVPVQHIRPVRAKKHK QSPGPVLPIVVQLMEMGFPRRNIEFALKSLTGASGNAAGLPGVEALVGWLLDHADVQVTD LSDADTGSEECSDEEVVEDVDDTAYAMSTGAVVTESQTYKKRADFLSNDDYAVYVRENIQ VGMMVRCCRTYEEVCEGDVGKVIKLDRDGLHDLNVQCDWQQKGGTYWVRYIHVELIESLG YPPPSSPSHIKIGDKVRVKASVTTPKYKWGSVTHQSVGVVKAFSANGKDVIVDFPQQSHW TGLLSEMELVPSVHPGVTCDGCQMFPINGSRFKCRNCDDFDFCEACFKTRKHNTRHTFGR INEPGQSAIFCGRSGKQLKRCHNSQPGMLLDSWARMVKSLNVSSSVNQASRLIDGSEPCW QSSGSQGKHWIRLEIFPDVLVHRLKMIVDPADSSYMPSLVVVSGGNSLNNLIELKTININ PTDTTVSLLNDCTEYHRYIEIAIKQCRSSGIDCKIHGLILLGRIRAEEEDMAAVPFLASD NEEEEDEKGNSGSLIRKKAAGLESAATIRTKVFVWGLNDKDQLGGLKGSKIKVPSFSETL SALNVVQVAGGSKSLFAVTVEGKVYACGEATNGRLGLGISSGTVPIPRQITALSSYVVKK VAVHSGGRHATALTVDGKVFSWGEGDDGKLGHFSRMNCDKPRLIEALKTKRIRDIACGSS HSAALTSSGELYTWGLGEYGRLGHGDNTTQLKPKMVKVLLGHRVIQVACGSRDAQTLALT DEGLVFSWGDGDFGKLGRGGSEGCNIPQNIERLNGQGVCQIECGAQFSLALTKSGVVWTW GKGDYFRLGHGSDVHVRKPQVVEGLRGKKIVHVAVGALHCLAVTDAGQVYAWGDNDHGQQ GNGTTTVNRKPTLVQGLEGQKITRVACGSSHSVAWTTVDVATPSVHEPVLFQTARDPLGA SYLGVPSDADSSPASNKINGANNSKPNRPSLAKILLSLDGNLAKQQALSHILTALQIMYA RDTVVGALMPAGMVAPVECPSFSSSAPASDVSAMASPMNGEECVLAVDIEDRLSPNPWQE KRGEIISSEDAVTPSAVTPSACSASSRPFIPVTDDPGAASIIAETMTKTKEDVESQNKVS GPELQSLDEFTSLLVVDDTRVLVDLLKLSVCGRAGDKGRDVLSAVLSGMGTAYPQVADML LELCVTELEDVATDSQSGRLSSQPVVVESSHPYTDDTSSSGTVKIPGAEGLRVEFDRQCS TERRHDPLTVMDGVNRIVSVRSGREWSDWSSELRIPGDELKWKFISDGSVNGWGWRFTVY PIMPAAGPKDLLSDRCVLSCPSMDLVTCLLDFRLNLASNRSIIPRLAASLAACAQLSALA ASHRMWALQRLRKLLTTEFGQSININRLLGDNDGETRALSFSGSALAALVKGLPEALQRQ FEYEDPIVRGGKQLLHSPFFKVLVALACDLELDTLPCCAETHKWAWFRRYCMASRVAVAL DKRTSLPRLFLDEVAKKIRELMADGENMDVLHESHSIFRREQDEQLVQWMNRRPDDWTLS AGGSGTIYGWGHNHRGQLGGIEGAKVKVPTPCEALAALRPVQLIGGEQTLFAVTADGKLY ATGYGAGGRLGVGGTESVSTPTLLESIQHVFIKKVAVNSGGKHCLALSSEGEVYSWGEAE DGKLGHGNRSPCDRPRVIESLRGTEVVDVAAGGAHSACVTAAGDLYTWGKGRYGRLGHSD SEDQLKPKLVEALQGHRVVDVACGSGDAQTLCLTDDDTVWSWGDGDYGKLGRGGSDGCKV PMKIDSLTGLGVVKVECGSQFSVALTKSGAVYTWGKGDYHRLGHGSDDHVRRPRQVQGLQ GKKVIAIATGSLHCVCCSEDGEVYTWGDNDEGQLGDGTTNAIQRPRLVAALQGKKVNRVA CGSAHTLAWSTSKPASAGKLPVQVPMEYNHLQEIPIIALRNRLLLLHHISELFCPCIPMF DLEGSLDETGLGPSVGFDTLRGILISQGKEAAFRKVVQATMVRDRQHGPVVELNRIQVKR SRSKGGLAGPDGTKSVFGQMCAKMTSFSPDSLLLPHRVWKVKFVGESVDDCGGGYSESIA EICEELQNGLTPLLIVTPNGRDESGANRDCYLFSPAARAPVHTNMFRFLGVLLGIAIRTG SPLSLNLAEPVWKQLAGMSLTIADLSEVDKDFIPGLMYIRDNEATSEEFEAMSLPFTVPS ASGQDIQLSSKYTHITLDNRAEYVRLAINYRLHEFDEQVAAVREGMARVVPVPLLSLFTG YELETMVCGSPDIPLHLLKSVATYKGVEPSAPLIQWFWEVMESFSNTERSLFLRFVWGRT RLPRTIADFRGRDFVIQVLDKYNPPDHFLPESYTCFFLLKLPRYSCKQVLEEKLKYAIHF CKSIDTDDYARIALTGEPAADDSSDDSENEDVDSFASDSTQDYLTGH

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ENSBTAP00000018496 (Bos taurus 76_3.1)

Protein sequence

Domain architecture