SUPERFAMILY 1.75 HMM library and genome assignments server

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Tlp20, baculovirus telokin-like protein superfamily

SCOP classification
Root:   SCOP hierarchy in SUPERFAMILY [ 0] (11)
Class:   All beta proteins [ 48724] (174)
Fold:   beta-clip [ 51268] (7)
Superfamily:   Tlp20, baculovirus telokin-like protein [ 51289]
Families:   Tlp20, baculovirus telokin-like protein [ 51290]

Superfamily statistics
Genomes (0) Uniprot 2018_03 genome PDB chains (SCOP 1.75)
Domains 0 125 1
Proteins 0 125 1

Functional annotation
General category Other
Detailed category Viral proteins

Function annotation of SCOP domain superfamilies

InterPro annotation
Cross references IPR009092 SSF51289 Protein matches

ACMNPV (Autographa californica nuclear polyhedrosis virus) telokin-like protein (TLP20) lies in a region of the baculoviral genome that is expressed late in the viral replication cycle, however its function is unknown. TLP20 was discovered using anti-telokin antibodies, telokin being the C-terminal domain of smooth-muscle myosin light-chain kinase [PubMed7517434]. Both TLP20 and telokin display a seven-stranded antiparallel beta-barrel structure, although the 3-dimensional structures of the beta-barrels are different and there is no sequence homology between the two. TLP20 is structurally similar to dUTPase in its fold and trimeric assembly.

InterPro database

PDBeMotif information about ligands, sequence and structure motifs
Cross references PDB entries
Ligand binding statistics
Nucleic-acid binding statistics
Occurrence of secondary structure elements
Occurrence of small 3D structural motifs

PDBeMotif resource

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Internal database links

Browse genome assignments for this superfamily. The SUPERFAMILY hidden Markov model library has been used to carry out SCOP domain assignments to all genomes at the superfamily level.

Alignments of sequences to 1 models in this superfamily are available by clicking on the 'Alignments' icon above. PDB sequences less than 40% identical are shown by default, but any other sequence(s) may be aligned. Select PDB sequences, genome sequences, or paste in or upload your own sequences.

Browse and view proteins in genomes which have different domain combinations including a Tlp20, baculovirus telokin-like protein domain.

Examine the distribution of domain superfamilies, or families, across the major taxonomic kingdoms or genomes within a kingdom. This gives an immediate impression of how superfamilies, or families, are restricted to certain kingdoms of life.

Explore domain occurrence network where nodes represent genomes and edges are domain architectures (shared between genomes) containing the superfamily of interest.

There are 1 hidden Markov models representing the Tlp20, baculovirus telokin-like protein superfamily. Information on how the models are built, and plots showing hydrophobicity, match emmission probabilities and insertion/deletion probabilities can be inspected.

Jump to [ Top of page · SCOP classification · InterPro annotation · PDBeMotif links · Functional annotation · Internal database links ]