Family Assignments

Domains Proteins SCOP Link Families
31 31 SCOP 52686 ABC transporter ATPase domain-like
16 13 SCOP 81269 Extended AAA-ATPase domain
11 11 SCOP 58105 Methyl-accepting chemotaxis protein (MCP) signaling domain
10 10 SCOP 52375 Class I aminoacyl-tRNA synthetases (RS), catalytic domain
10 10 SCOP 55682 Class II aminoacyl-tRNA synthetase (aaRS)-like, catalytic domain
10 7 SCOP 81268 Tandem AAA-ATPase domain
9 9 SCOP 51446 Amylase, catalytic domain
9 9 SCOP 51751 Tyrosine-dependent oxidoreductases
9 9 SCOP 53823 L-arabinose binding protein-like
7 7 SCOP 52592 G proteins
7 7 SCOP 53417 GABA-aminotransferase-like
7 7 SCOP 53851 Phosphate binding protein-like
6 6 SCOP 51487 beta-glycanases
6 6 SCOP 52652 Nitrogenase iron protein-like
6 6 SCOP 161099 MetI-like
5 5 SCOP 52318 Class I glutamine amidotransferases (GAT)
5 5 SCOP 52670 RecA protein-like (ATPase-domain)
5 5 SCOP 53402 Cystathionine synthase-like
5 5 SCOP 53687 Tryptophan synthase beta subunit-like PLP-dependent enzymes
5 5 SCOP 63588 Glycosyltransferase family 36 C-terminal domain
4 4 SCOP 51570 Class I aldolase
4 2 SCOP 53068 Actin/HSP70
4 4 SCOP 53168 Purine and uridine phosphorylases
4 4 SCOP 142721 PyrH-like
3 3 SCOP 48234 Hyaluronate lyase-like catalytic, N-terminal domain
3 3 SCOP 48558 L-aspartase/fumarase
3 3 SCOP 50282 Cold shock DNA-binding domain-like
3 3 SCOP 50678 ValRS/IleRS/LeuRS editing domain
3 3 SCOP 51396 FMN-linked oxidoreductases
3 3 SCOP 51431 Aldo-keto reductases (NADP)
3 3 SCOP 51868 6-phosphogluconate dehydrogenase-like, N-terminal domain
3 3 SCOP 52403 N-type ATP pyrophosphatases
3 3 SCOP 52739 Methylesterase CheB, C-terminal domain
3 3 SCOP 53272 Phosphoribosyltransferases (PRTases)
3 3 SCOP 53329 Formyltransferase
3 3 SCOP 53614 Ribokinase-like
3 3 SCOP 53785 Phosphofructokinase
3 2 SCOP 53902 Thiolase-related
3 3 SCOP 54212 Translational machinery components
3 3 SCOP 55879 DNA gyrase/MutL, N-terminal domain
3 3 SCOP 55884 Histidine kinase
3 1 SCOP 55974 S-adenosylmethionine synthetase
3 2 SCOP 56067 BC ATP-binding domain-like
3 3 SCOP 56236 Class II glutamine amidotransferases
3 3 SCOP 56802 Acetyl-CoA synthetase-like
3 2 SCOP 63412 MPP-like
3 3 SCOP 64519 Phase 1 flagellin
3 3 SCOP 75459 Pseudouridine synthase RsuA/RluD
3 3 SCOP 88724 Pyruvate oxidase and decarboxylase Pyr module
2 2 SCOP 47241 Ferritin
2 2 SCOP 47324 Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases
2 2 SCOP 48030 FliG
2 2 SCOP 48257 Citrate synthase
2 2 SCOP 50006 Hyaluronate lyase-like, central domain
2 2 SCOP 50448 Elongation factors
2 2 SCOP 50495 Prokaryotic proteases
2 2 SCOP 51420 Alanine racemase-like, N-terminal domain
2 2 SCOP 51599 Class I DAHP synthetase
2 2 SCOP 51629 Pyruvate phosphate dikinase, C-terminal domain
2 2 SCOP 51800 Glyceraldehyde-3-phosphate dehydrogenase-like, N-terminal domain
2 2 SCOP 51848 LDH N-terminal domain-like
2 2 SCOP 51883 Aminoacid dehydrogenase-like, C-terminal domain
2 2 SCOP 52097 Clp protease, ClpP subunit
2 1 SCOP 52441 BC N-terminal domain-like
2 2 SCOP 52541 Nucleotide and nucleoside kinases
2 1 SCOP 53080 Acetokinase-like
2 1 SCOP 53089 Glycerol kinase
2 2 SCOP 53099 Ribonuclease H
2 2 SCOP 53138 Ribosomal protein L18 and S11
2 2 SCOP 53384 AAT-like
2 2 SCOP 53464 glucose-1-phosphate thymidylyltransferase
2 2 SCOP 53640 AraD-like aldolase/epimerase
2 2 SCOP 53660 Dimeric isocitrate & isopropylmalate dehydrogenases
2 2 SCOP 53672 Aspartate/ornithine carbamoyltransferase
2 2 SCOP 53721 ALDH-like
2 2 SCOP 53733 Aconitase iron-sulfur domain
2 2 SCOP 53811 TroA-like
2 2 SCOP 53921 Fe-only hydrogenase
2 1 SCOP 54229 Ribonuclease PH domain 1-like
2 2 SCOP 55074 Adenylyl and guanylyl cyclase catalytic domain
2 2 SCOP 55209 Enolpyruvate transferase, EPT
2 2 SCOP 55348 GAPDH-like
2 2 SCOP 55730 N-acetyl transferase, NAT
2 2 SCOP 55921 Creatinase/aminopeptidase
2 2 SCOP 56307 5'-nucleotidase (syn. UDP-sugar hydrolase), N-terminal domain
2 2 SCOP 56328 Lactate & malate dehydrogenases, C-terminal domain
2 2 SCOP 56350 Lambda integrase-like, catalytic core
2 2 SCOP 56720 Type II DNA topoisomerase
2 2 SCOP 56797 Dehydroquinate synthase, DHQS
2 2 SCOP 63733 Glycosyltransferase family 36 N-terminal domain
2 2 SCOP 75173 beta-Phosphoglucomutase-like
2 2 SCOP 75621 Release factor
2 2 SCOP 75648 ABC transporter involved in vitamin B12 uptake, BtuC
2 2 SCOP 82261 N-acetylglucosamine-6-phosphate deacetylase, NagA, catalytic domain
2 2 SCOP 82267 TatD Mg-dependent DNase-like
2 1 SCOP 82867 Multidrug efflux transporter AcrB transmembrane domain
2 2 SCOP 88749 Pyruvate oxidase and decarboxylase PP module
2 2 SCOP 88947 Sigma2 domain of RNA polymerase sigma factors
2 2 SCOP 89494 HMGL-like
2 1 SCOP 89572 Biotin dependent carboxylase carboxyltransferase domain
2 2 SCOP 101340 HD domain
2 2 SCOP 110284 TM1225-like predicted glycosylases
2 1 SCOP 110384 Cobalamin-independent methionine synthase
2 2 SCOP 110734 Glycosyl transferases group 1
2 2 SCOP 111353 Ammonium transporter
2 2 SCOP 117984 GGDEF domain
2 2 SCOP 140991 FtsH protease domain-like
2 2 SCOP 143812 GatB/GatE catalytic domain-like
2 1 SCOP 143860 Polyphosphate kinase C-terminal domain
2 2 SCOP 159832 PBP transglycosylase domain-like
1 1 SCOP 46566 Chaperone J-domain
1 1 SCOP 46907 Ribosomal protein L11, C-terminal domain
1 1 SCOP 46947 Ribosomal protein S13
1 1 SCOP 47253 Ribonucleotide reductase-like
1 1 SCOP 47974 Ribosomal protein S7
1 1 SCOP 48151 Endonuclease III
1 1 SCOP 48191 UDP-glucose/GDP-mannose dehydrogenase dimerisation domain
1 1 SCOP 48222 N-acylglucosamine (NAG) epimerase
1 1 SCOP 48335 DNA repair protein MutS, domain III
1 1 SCOP 48404 Ankyrin repeat
1 1 SCOP 48593 GroEL chaperone, ATPase domain
1 1 SCOP 49803 beta-Galactosidase/glucuronidase, N-terminal domain
1 1 SCOP 50114 C-terminal domain of ribosomal protein L2
1 1 SCOP 50194 Ribosomal protein L14
1 1 SCOP 50342 CheW-like
1 1 SCOP 50444 L-fucose isomerase, C-terminal domain
1 1 SCOP 50461 Ribosomal protein L3
1 1 SCOP 50466 EF-Tu/eEF-1alpha/eIF2-gamma C-terminal domain
1 1 SCOP 50892 Cyclophilin (peptidylprolyl isomerase)
1 1 SCOP 51127 Pectate lyase-like
1 1 SCOP 51171 GlmU C-terminal domain-like
1 1 SCOP 51183 dTDP-sugar isomerase
1 1 SCOP 51191 Type I phosphomannose isomerase
1 1 SCOP 51284 dUTPase-like
1 1 SCOP 51352 Triosephosphate isomerase (TIM)
1 1 SCOP 51367 Histidine biosynthesis enzymes
1 1 SCOP 51372 D-ribulose-5-phosphate 3-epimerase
1 1 SCOP 51381 Tryptophan biosynthesis enzymes
1 1 SCOP 51413 Inosine monophosphate dehydrogenase (IMPDH)
1 1 SCOP 51521 Family 1 of glycosyl hydrolase
1 1 SCOP 51534 Type II chitinase
1 1 SCOP 51550 beta-N-acetylhexosaminidase catalytic domain
1 1 SCOP 51553 NagZ-like
1 1 SCOP 51591 Class II FBP aldolase
1 1 SCOP 51605 Enolase
1 1 SCOP 51622 Pyruvate kinase
1 1 SCOP 51659 Endonuclease IV
1 1 SCOP 51691 NadC C-terminal domain-like
1 1 SCOP 51714 tRNA-guanine transglycosylase
1 1 SCOP 51718 Dihydropteroate synthetase
1 1 SCOP 51723 Methyltetrahydrofolate-utiluzing methyltransferases
1 1 SCOP 51731 Methylenetetrahydrofolate reductase
1 1 SCOP 51934 Succinate dehydrogenase/fumarate reductase flavoprotein N-terminal domain
1 1 SCOP 51999 PFL-like
1 1 SCOP 52002 R1 subunit of ribonucleotide reductase, C-terminal domain
1 1 SCOP 52017 LeuD-like
1 1 SCOP 52022 Carbamoyl phosphate synthetase, small subunit N-terminal domain
1 1 SCOP 52030 GroEL-like chaperone, apical domain
1 1 SCOP 52100 Tail specific protease, catalytic domain
1 1 SCOP 52147 Mug-like
1 1 SCOP 52152 FabD-like
1 1 SCOP 52162 Ribosomal protein L13
1 1 SCOP 52167 Ribosomal protein L4
1 1 SCOP 52173 CheY-related
1 1 SCOP 52256 N5-CAIR mutase (phosphoribosylaminoimidazole carboxylase, PurE)
1 1 SCOP 52314 Ribosomal protein S2
1 1 SCOP 52397 Adenylyltransferase
1 1 SCOP 52419 Nucleoside phosphorylase/phosphoribosyltransferase catalytic domain
1 1 SCOP 52475 Pyruvate oxidase and decarboxylase, middle domain
1 1 SCOP 52491 Tubulin, GTPase domain
1 1 SCOP 52513 NagB-like
1 1 SCOP 52769 Arginase-like amidino hydrolases
1 1 SCOP 52901 Glutathione peroxidase-like
1 1 SCOP 52931 Pyruvate-ferredoxin oxidoreductase, PFOR, domain II
1 1 SCOP 52973 ITPase (Ham1)
1 1 SCOP 52976 Maf-like
1 1 SCOP 53045 5' to 3' exonuclease catalytic domain
1 1 SCOP 53179 Peptidyl-tRNA hydrolase-like
1 1 SCOP 53204 Bacterial dinuclear zinc exopeptidases
1 1 SCOP 53224 Aminoacid dehydrogenases
1 1 SCOP 53235 Tetrahydrofolate dehydrogenase/cyclohydrolase
1 1 SCOP 53324 Pyruvate-ferredoxin oxidoreductase, PFOR, domain III
1 1 SCOP 53357 Chemotaxis receptor methyltransferase CheR, C-terminal domain
1 1 SCOP 53525 Epoxide hydrolase
1 1 SCOP 53629 Folylpolyglutamate synthetase
1 1 SCOP 53698 double-SIS domain
1 1 SCOP 53701 Phosphoglucose isomerase, PGI
1 1 SCOP 53744 L-fucose isomerase, N-terminal and second domains
1 1 SCOP 53749 Phosphoglycerate kinase
1 1 SCOP 53763 UDP-N-acetylglucosamine 2-epimerase
1 1 SCOP 53766 Oligosaccharide phosphorylase
1 1 SCOP 53796 PEP carboxykinase C-terminal domain
1 1 SCOP 53914 Chalcone synthase-like
1 1 SCOP 54066 DNA/RNA non-specific endonuclease
1 1 SCOP 54224 DNA gyrase/MutL, second domain
1 1 SCOP 54232 GHMP Kinase, N-terminal domain
1 1 SCOP 54365 Translation initiation factor IF3, N-terminal domain
1 1 SCOP 54571 Ribosomal protein S19
1 1 SCOP 54822 Ribosomal protein S3 C-terminal domain
1 1 SCOP 54827 Enolase N-terminal domain-like
1 1 SCOP 54920 Nucleoside diphosphate kinase, NDK
1 1 SCOP 55000 Ribosomal protein S10
1 1 SCOP 55069 Peptide methionine sulfoxide reductase
1 1 SCOP 55121 Pseudouridine synthase I TruA
1 1 SCOP 55178 Ribosomal protein S4
1 1 SCOP 55187 Threonyl-tRNA synthetase (ThrRS), second 'additional' domain
1 1 SCOP 55195 Ribosome recycling factor, RRF
1 1 SCOP 55272 DNA repair protein MutS, domain I
1 1 SCOP 55283 Ribosomal protein L5
1 1 SCOP 55299 YjgF/L-PSP
1 1 SCOP 55308 Tubulin, C-terminal domain
1 1 SCOP 55327 PurM N-terminal domain-like
1 1 SCOP 55363 Homoserine dehydrogenase-like
1 1 SCOP 55368 Dihydrodipicolinate reductase-like
1 1 SCOP 55817 5'-nucleotidase (syn. UDP-sugar hydrolase), C-terminal domain
1 1 SCOP 55875 Heat shock protein 90, HSP90, N-terminal domain
1 1 SCOP 55932 Glutamine synthetase catalytic domain
1 1 SCOP 56043 PurM C-terminal domain-like
1 1 SCOP 56048 Ribosomal protein S8
1 1 SCOP 56085 Pyruvate phosphate dikinase, N-terminal domain
1 1 SCOP 56096 Adenylation domain of NAD+-dependent DNA ligase
1 1 SCOP 56105 SAICAR synthase
1 1 SCOP 56220 DNase I-like
1 1 SCOP 56251 Proteasome subunits
1 1 SCOP 56323 ADC synthase
1 1 SCOP 56421 Peptide deformylase
1 1 SCOP 56426 Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain
1 1 SCOP 56602 beta-Lactamase/D-ala carboxypeptidase
1 1 SCOP 56635 Heme-dependent catalases
1 1 SCOP 56673 DNA polymerase I
1 1 SCOP 56713 Prokaryotic type I DNA topoisomerase
1 1 SCOP 56732 DNA primase DnaG catalytic core
1 1 SCOP 56753 D-aminoacid aminotransferase-like PLP-dependent enzymes
1 1 SCOP 56809 Ribosomal protein L1
1 1 SCOP 56822 Hybrid cluster protein (prismane protein)
1 1 SCOP 57939 DnaJ/Hsp40 cysteine-rich domain
1 1 SCOP 63971 Inosicase
1 1 SCOP 63984 Sir2 family of transcriptional regulators
1 1 SCOP 64006 Undecaprenyl diphosphate synthase
1 1 SCOP 64159 2,3-Bisphosphoglycerate-independent phosphoglycerate mutase, substrate-binding domain
1 1 SCOP 64162 2,3-Bisphosphoglycerate-independent phosphoglycerate mutase, catalytic domain
1 1 SCOP 64168 SurE-like
1 1 SCOP 64183 Manganese-dependent inorganic pyrophosphatase (family II)
1 1 SCOP 64186 HPr kinase HprK C-terminal domain
1 1 SCOP 64198 AICAR transformylase domain of bifunctional purine biosynthesis enzyme ATIC
1 1 SCOP 64264 Prokaryotic ribosomal protein L17
1 1 SCOP 64485 RNA-polymerase beta
1 1 SCOP 64490 RNA-polymerase beta-prime
1 1 SCOP 68901 Cytidylytransferase
1 1 SCOP 68924 PEP carboxykinase N-terminal domain
1 1 SCOP 69427 UDP-galactopyranose mutase, N-terminal domain
1 1 SCOP 69602 L-histidinol dehydrogenase HisD
1 1 SCOP 69746 Pseudouridine synthase II TruB
1 1 SCOP 69766 IpsF-like
1 1 SCOP 69797 Thymidylate synthase-complementing protein Thy1
1 1 SCOP 69865 Argininosuccinate synthetase, C-terminal domain
1 1 SCOP 69892 Iron-containing alcohol dehydrogenase
1 1 SCOP 74732 Ribosomal protein L20
1 1 SCOP 74756 3-Methyladenine DNA glycosylase I (Tag)
1 1 SCOP 74911 Aldose 1-epimerase (mutarotase)
1 1 SCOP 74983 Small protein B (SmpB)
1 1 SCOP 75041 SelR domain
1 1 SCOP 75073 Hydantoinase (dihydropyrimidinase), catalytic domain
1 1 SCOP 75082 Uronate isomerase-like
1 1 SCOP 75218 SpoU-like RNA 2'-O ribose methyltransferase
1 1 SCOP 75297 N-acetyl-l-glutamate kinase
1 1 SCOP 75305 Amidase signature (AS) enzymes
1 1 SCOP 75513 IclR ligand-binding domain-like
1 1 SCOP 75626 YebC-like
1 1 SCOP 81768 Pre-protein crosslinking domain of SecA
1 1 SCOP 81887 Helical scaffold and wing domains of SecA
1 1 SCOP 82052 Obg GTP-binding protein N-terminal domain
1 1 SCOP 82283 Homocysteine S-methyltransferase
1 1 SCOP 82583 G domain-linked domain
1 1 SCOP 82661 Poly A polymerase head domain-like
1 1 SCOP 88682 Alanine racemase
1 1 SCOP 88683 Eukaryotic ODC-like
1 1 SCOP 88704 Phosphoenolpyruvate mutase/Isocitrate lyase-like
1 1 SCOP 88735 TK-like Pyr module
1 1 SCOP 88746 PFOR Pyr module
1 1 SCOP 88760 TK-like PP module
1 1 SCOP 88771 PFOR PP module
1 1 SCOP 88854 Protein kinases, catalytic subunit
1 1 SCOP 89108 Hypothetical protein YteR
1 1 SCOP 89624 Ribose/Galactose isomerase RpiB/AlsB
1 1 SCOP 89629 tRNA(m1G37)-methyltransferase TrmD
1 1 SCOP 89743 N5-glutamine methyltransferase, HemK
1 1 SCOP 90124 ABC transporter transmembrane region
1 1 SCOP 100888 Lesion bypass DNA polymerase (Y-family), catalytic domain
1 1 SCOP 100921 Heat shock protein 70kD (HSP70), peptide-binding domain
1 1 SCOP 100935 Heat shock protein 70kD (HSP70), C-terminal subdomain
1 1 SCOP 101354 Putative anticodon-binding domain of alanyl-tRNA synthetase (AlaRS)
1 1 SCOP 101802 Surface presentation of antigens (SPOA)
1 1 SCOP 101905 GyrA/ParC C-terminal domain-like
1 1 SCOP 101951 Pectate transeliminase
1 1 SCOP 102189 AmyC N-terminal domain-like
1 1 SCOP 102304 Homoserine kinase ThrH
1 1 SCOP 102547 RbsD-like
1 1 SCOP 102656 PdxA-like
1 1 SCOP 102663 Phosphotransacetylase
1 1 SCOP 102706 NIF3 (NGG1p interacting factor 3)-like
1 1 SCOP 102755 Hsp90 middle domain
1 1 SCOP 102769 ATP-dependent protease Lon (La), catalytic domain
1 1 SCOP 102928 NifU/IscU domain
1 1 SCOP 102945 RelA/SpoT domain
1 1 SCOP 103011 Galactokinase
1 1 SCOP 103264 Chorismate synthase, AroC
1 1 SCOP 109710 KorB DNA-binding domain-like
1 1 SCOP 109725 Conserved carboxylase domain
1 1 SCOP 109756 PhoU-like
1 1 SCOP 110318 KduI-like
1 1 SCOP 110368 NeuB-like
1 1 SCOP 110377 UxuA-like
1 1 SCOP 110396 CutC-like
1 1 SCOP 110943 HSP90 C-terminal domain
1 1 SCOP 111219 ArgJ-like
1 1 SCOP 111233 YfcE-like
1 1 SCOP 111305 Recombination protein RecR
1 1 SCOP 111338 QueA-like
1 1 SCOP 117144 Flagellar hook protein flgE
1 1 SCOP 117888 Ribosomal protein L16p
1 1 SCOP 140479 LemA-like
1 1 SCOP 141819 PP1699/LP2961-like
1 1 SCOP 142020 Nqo1 FMN-binding domain-like
1 1 SCOP 142077 HTS-like
1 1 SCOP 142093 ThiI-like
1 1 SCOP 142606 N-6 DNA Methylase-like
1 1 SCOP 142635 hypothetical RNA methyltransferase
1 1 SCOP 142735 DeoB catalytic domain-like
1 1 SCOP 143598 YojJ-like
1 1 SCOP 143632 ApbE-like
1 1 SCOP 143711 LFTR-like
1 1 SCOP 143857 DeoB insert domain-like
1 1 SCOP 143916 RNase Z-like
1 1 SCOP 143927 beta-CASP RNA-metabolising hydrolases
1 1 SCOP 143976 lvD/EDD N-terminal domain-like
1 1 SCOP 158600 MgsA/YrvN C-terminal domain-like
1 1 SCOP 158607 AadK C-terminal domain-like
1 1 SCOP 158833 Tex N-terminal region-like
1 1 SCOP 159112 RNB domain-like
1 1 SCOP 159444 SP0239-like
1 1 SCOP 159635 Tex RuvX-like domain-like
1 1 SCOP 159700 LPG1296-like
1 1 SCOP 159720 mannose-1-phosphate guanylyl transferase
1 1 SCOP 160257 AadK N-terminal domain-like
1 1 SCOP 160370 Ribosomal protein L10-like
1 1 SCOP 160538 SpoVG-like

The following families have one or more weak hits: