Family Assignments

Domains Proteins SCOP Link Families
28 28 SCOP 52686 ABC transporter ATPase domain-like
22 22 SCOP 56802 Acetyl-CoA synthetase-like
12 12 SCOP 47204 Medium chain acyl-CoA dehydrogenase-like, C-terminal domain
12 12 SCOP 51868 6-phosphogluconate dehydrogenase-like, N-terminal domain
12 12 SCOP 56646 Medium chain acyl-CoA dehydrogenase, NM (N-terminal and middle) domains
10 9 SCOP 52211 Succinyl-CoA synthetase domains
9 9 SCOP 52103 Crotonase-like
9 9 SCOP 52375 Class I aminoacyl-tRNA synthetases (RS), catalytic domain
9 9 SCOP 53851 Phosphate binding protein-like
8 8 SCOP 51396 FMN-linked oxidoreductases
8 6 SCOP 81269 Extended AAA-ATPase domain
7 7 SCOP 52318 Class I glutamine amidotransferases (GAT)
7 7 SCOP 52652 Nitrogenase iron protein-like
7 7 SCOP 55682 Class II aminoacyl-tRNA synthetase (aaRS)-like, catalytic domain
6 6 SCOP 51900 CoA-binding domain
6 6 SCOP 52592 G proteins
6 6 SCOP 53384 AAT-like
5 5 SCOP 51751 Tyrosine-dependent oxidoreductases
5 5 SCOP 53791 Tetrapyrrole methylase
5 3 SCOP 53902 Thiolase-related
5 4 SCOP 81268 Tandem AAA-ATPase domain
5 5 SCOP 89797 CoA-transferase family III (CaiB/BaiF)
4 4 SCOP 52403 N-type ATP pyrophosphatases
4 4 SCOP 53417 GABA-aminotransferase-like
4 4 SCOP 53687 Tryptophan synthase beta subunit-like PLP-dependent enzymes
4 4 SCOP 53707 Formate dehydrogenase/DMSO reductase, domains 1-3
4 2 SCOP 55113 Formylmethanofuran:tetrahydromethanopterin formyltransferase
4 3 SCOP 56067 BC ATP-binding domain-like
4 4 SCOP 56229 Aldehyde ferredoxin oxidoreductase, N-terminal domain
3 3 SCOP 48311 Aldehyde ferredoxin oxidoreductase, C-terminal domains
3 3 SCOP 50282 Cold shock DNA-binding domain-like
3 3 SCOP 50448 Elongation factors
3 3 SCOP 51570 Class I aldolase
3 3 SCOP 51800 Glyceraldehyde-3-phosphate dehydrogenase-like, N-terminal domain
3 3 SCOP 52419 Nucleoside phosphorylase/phosphoribosyltransferase catalytic domain
3 2 SCOP 52441 BC N-terminal domain-like
3 3 SCOP 52670 RecA protein-like (ATPase-domain)
3 2 SCOP 53089 Glycerol kinase
3 3 SCOP 53402 Cystathionine synthase-like
3 3 SCOP 56043 PurM C-terminal domain-like
3 3 SCOP 63883 MoeA N-terminal region -like
3 3 SCOP 69892 Iron-containing alcohol dehydrogenase
3 3 SCOP 82636 MaoC-like
3 3 SCOP 101340 HD domain
3 3 SCOP 102575 NOL1/NOP2/sun
3 3 SCOP 111353 Ammonium transporter
2 2 SCOP 46978 Succinate dehydrogenase/fumarate reductase flavoprotein C-terminal domain
2 2 SCOP 47241 Ferritin
2 1 SCOP 47965 Transcription factor IIB (TFIIB), core domain
2 2 SCOP 48558 L-aspartase/fumarase
2 2 SCOP 48596 Group II chaperonin (CCT, TRIC), ATPase domain
2 2 SCOP 49368 Superoxide reductase-like
2 2 SCOP 50183 Sm motif of small nuclear ribonucleoproteins, SNRNP
2 2 SCOP 50466 EF-Tu/eEF-1alpha/eIF2-gamma C-terminal domain
2 2 SCOP 51650 RuBisCo, large subunit, C-terminal domain
2 2 SCOP 51691 NadC C-terminal domain-like
2 2 SCOP 51704 Methylmalonyl-CoA mutase, N-terminal (CoA-binding) domain
2 2 SCOP 51714 tRNA-guanine transglycosylase
2 2 SCOP 51830 Formate/glycerate dehydrogenases, NAD-domain
2 2 SCOP 51883 Aminoacid dehydrogenase-like, C-terminal domain
2 2 SCOP 51934 Succinate dehydrogenase/fumarate reductase flavoprotein N-terminal domain
2 2 SCOP 52017 LeuD-like
2 2 SCOP 52034 Group II chaperonin (CCT, TRIC), apical domain
2 2 SCOP 52243 Cobalamin (vitamin B12)-binding domain
2 2 SCOP 52397 Adenylyltransferase
2 2 SCOP 52468 Deoxyhypusine synthase, DHS
2 2 SCOP 52491 Tubulin, GTPase domain
2 1 SCOP 53033 tRNA-intron endonuclease catalytic domain-like
2 2 SCOP 53354 Protein-L-isoaspartyl O-methyltransferase
2 2 SCOP 53620 Thiamin biosynthesis kinases
2 2 SCOP 53660 Dimeric isocitrate & isopropylmalate dehydrogenases
2 2 SCOP 53672 Aspartate/ornithine carbamoyltransferase
2 2 SCOP 53733 Aconitase iron-sulfur domain
2 2 SCOP 54224 DNA gyrase/MutL, second domain
2 2 SCOP 54229 Ribonuclease PH domain 1-like
2 2 SCOP 54914 Prokaryotic signal transducing protein
2 1 SCOP 55268 tRNA-intron endonuclease N-terminal domain-like
2 2 SCOP 55308 Tubulin, C-terminal domain
2 2 SCOP 55348 GAPDH-like
2 2 SCOP 55667 Ribonuclease PH domain 2-like
2 2 SCOP 55921 Creatinase/aminopeptidase
2 1 SCOP 55983 DNA polymerase processivity factor
2 2 SCOP 56015 Nitrite and sulphite reductase 4Fe-4S domain-like
2 2 SCOP 56081 Succinyl-CoA synthetase, beta-chain, N-terminal domain
2 2 SCOP 56251 Proteasome subunits
2 2 SCOP 56291 ROO N-terminal domain-like
2 2 SCOP 56426 Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain
2 2 SCOP 56530 FAH
2 2 SCOP 56673 DNA polymerase I
2 2 SCOP 56713 Prokaryotic type I DNA topoisomerase
2 2 SCOP 58105 Methyl-accepting chemotaxis protein (MCP) signaling domain
2 2 SCOP 63984 Sir2 family of transcriptional regulators
2 2 SCOP 64103 MoeA central domain-like
2 2 SCOP 64485 RNA-polymerase beta
2 2 SCOP 64490 RNA-polymerase beta-prime
2 1 SCOP 69496 Helicase-like "domain" of reverse gyrase
2 1 SCOP 74753 Catalase-peroxidase KatG
2 2 SCOP 75305 Amidase signature (AS) enzymes
2 2 SCOP 75648 ABC transporter involved in vitamin B12 uptake, BtuC
2 2 SCOP 82258 SAH/MTA deaminase-like
2 2 SCOP 88724 Pyruvate oxidase and decarboxylase Pyr module
2 2 SCOP 89156 TorD-like
2 1 SCOP 89572 Biotin dependent carboxylase carboxyltransferase domain
2 2 SCOP 89619 PIN domain
2 2 SCOP 102928 NifU/IscU domain
2 2 SCOP 110513 IF2B-like
2 2 SCOP 111284 Putative modulator of DNA gyrase, PmbA/TldD
2 2 SCOP 142721 PyrH-like
2 2 SCOP 143812 GatB/GatE catalytic domain-like
2 2 SCOP 143927 beta-CASP RNA-metabolising hydrolases
2 1 SCOP 143979 Type I restriction modification DNA specificity domain
2 2 SCOP 159704 SepSecS-like
2 2 SCOP 160336 DsrA/DsrB N-terminal-domain-like
2 2 SCOP 160804 PurP ATP-binding domain-like
1 1 SCOP 46549 Fumarate reductase/Succinate dehydogenase iron-sulfur protein, C-terminal domain
1 1 SCOP 46580 Prefoldin
1 1 SCOP 46801 ArsR-like transcriptional regulators
1 1 SCOP 47324 Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases
1 1 SCOP 47447 Signal peptide-binding domain
1 1 SCOP 47808 5' to 3' exonuclease, C-terminal subdomain
1 1 SCOP 47974 Ribosomal protein S7
1 1 SCOP 48020 DNA polymerase III clamp loader subunits, C-terminal domain
1 1 SCOP 48109 Carbamoyl phosphate synthetase, large subunit connection domain
1 1 SCOP 48141 Ribosomal protein L19 (L19e)
1 1 SCOP 48184 Acetohydroxy acid isomeroreductase (ketol-acid reductoisomerase, KARI)
1 1 SCOP 48197 Glycerol-3-phosphate dehydrogenase
1 1 SCOP 48257 Citrate synthase
1 1 SCOP 48577 Isoprenyl diphosphate synthases
1 1 SCOP 50114 C-terminal domain of ribosomal protein L2
1 1 SCOP 50194 Ribosomal protein L14
1 1 SCOP 50277 Myf domain
1 1 SCOP 50461 Ribosomal protein L3
1 1 SCOP 50482 NADH:FMN oxidoreductase-like
1 1 SCOP 50678 ValRS/IleRS/LeuRS editing domain
1 1 SCOP 51191 Type I phosphomannose isomerase
1 1 SCOP 51247 BC C-terminal domain-like
1 1 SCOP 51352 Triosephosphate isomerase (TIM)
1 1 SCOP 51367 Histidine biosynthesis enzymes
1 1 SCOP 51375 Decarboxylase
1 1 SCOP 51381 Tryptophan biosynthesis enzymes
1 1 SCOP 51392 Thiamin phosphate synthase
1 1 SCOP 51420 Alanine racemase-like, N-terminal domain
1 1 SCOP 51594 5-aminolaevulinate dehydratase, ALAD (porphobilinogen synthase)
1 1 SCOP 51605 Enolase
1 1 SCOP 51687 F420 dependent oxidoreductases
1 1 SCOP 51848 LDH N-terminal domain-like
1 1 SCOP 51999 PFL-like
1 1 SCOP 52022 Carbamoyl phosphate synthetase, small subunit N-terminal domain
1 1 SCOP 52043 Ribosomal protein L32e
1 1 SCOP 52081 Ribosomal proteins L15p and L18e
1 1 SCOP 52147 Mug-like
1 1 SCOP 52157 Initiation factor IF2/eIF5b, domain 3
1 1 SCOP 52162 Ribosomal protein L13
1 1 SCOP 52167 Ribosomal protein L4
1 1 SCOP 52173 CheY-related
1 1 SCOP 52256 N5-CAIR mutase (phosphoribosylaminoimidazole carboxylase, PurE)
1 1 SCOP 52300 S-adenosylhomocystein hydrolase
1 1 SCOP 52314 Ribosomal protein S2
1 1 SCOP 52325 DJ-1/PfpI
1 1 SCOP 52432 ETFP subunits
1 1 SCOP 52471 C-terminal domain of the electron transfer flavoprotein alpha subunit
1 1 SCOP 52475 Pyruvate oxidase and decarboxylase, middle domain
1 1 SCOP 52508 Homo-oligomeric flavin-containing Cys decarboxylases, HFCD
1 1 SCOP 52541 Nucleotide and nucleoside kinases
1 1 SCOP 52739 Methylesterase CheB, C-terminal domain
1 1 SCOP 52744 Subtilases
1 1 SCOP 52769 Arginase-like amidino hydrolases
1 1 SCOP 52773 Histone deacetylase, HDAC
1 1 SCOP 52789 Low-molecular-weight phosphotyrosine protein phosphatases
1 1 SCOP 52901 Glutathione peroxidase-like
1 1 SCOP 52955 Anticodon-binding domain of Class II aaRS
1 1 SCOP 52973 ITPase (Ham1)
1 1 SCOP 53045 5' to 3' exonuclease catalytic domain
1 1 SCOP 53099 Ribonuclease H
1 1 SCOP 53118 DnaQ-like 3'-5' exonuclease
1 1 SCOP 53138 Ribosomal protein L18 and S11
1 1 SCOP 53168 Purine and uridine phosphorylases
1 1 SCOP 53204 Bacterial dinuclear zinc exopeptidases
1 1 SCOP 53240 Malic enzyme N-domain
1 1 SCOP 53272 Phosphoribosyltransferases (PRTases)
1 1 SCOP 53339 RNA methyltransferase FtsJ
1 1 SCOP 53342 Fibrillarin homologue
1 1 SCOP 53464 glucose-1-phosphate thymidylyltransferase
1 1 SCOP 53487 Carboxylesterase
1 1 SCOP 53749 Phosphoglycerate kinase
1 1 SCOP 53775 Glutaminase/Asparaginase
1 1 SCOP 54002 Papain-like
1 1 SCOP 54193 L15e
1 1 SCOP 54212 Translational machinery components
1 1 SCOP 54535 FKBP immunophilin/proline isomerase
1 1 SCOP 54676 NadC N-terminal domain-like
1 1 SCOP 54687 Ribosomal protein L10e
1 1 SCOP 54792 Eukaryotic type KH-domain (KH-domain type I)
1 1 SCOP 54811 GMP synthetase C-terminal dimerisation domain
1 1 SCOP 54844 Ribosomal protein L22
1 1 SCOP 54884 Ferredoxin domains from multidomain proteins
1 1 SCOP 54894 Aspartate carbamoyltransferase, Regulatory-chain, N-terminal domain
1 1 SCOP 54920 Nucleoside diphosphate kinase, NDK
1 1 SCOP 54967 Ribulose 1,5-bisphosphate carboxylase-oxygenase
1 1 SCOP 55036 NAD-binding domain of HMG-CoA reductase
1 1 SCOP 55041 Molybdenum cofactor biosynthesis protein C, MoaC
1 1 SCOP 55121 Pseudouridine synthase I TruA
1 1 SCOP 55130 Ribosomal protein L30p/L7e
1 1 SCOP 55206 RNA 3'-terminal phosphate cyclase, RPTC
1 1 SCOP 55209 Enolpyruvate transferase, EPT
1 1 SCOP 55262 GAD domain
1 1 SCOP 55283 Ribosomal protein L5
1 1 SCOP 55316 L30e/L7ae ribosomal proteins
1 1 SCOP 55327 PurM N-terminal domain-like
1 1 SCOP 55368 Dihydrodipicolinate reductase-like
1 1 SCOP 55482 N-terminal domain of eukaryotic peptide chain release factor subunit 1, ERF1
1 1 SCOP 55822 YrdC-like
1 1 SCOP 55884 Histidine kinase
1 1 SCOP 55910 Ribosome anti-association factor eIF6 (aIF6)
1 1 SCOP 55932 Glutamine synthetase catalytic domain
1 1 SCOP 55946 TATA-box binding protein (TBP), C-terminal domain
1 1 SCOP 56048 Ribosomal protein S8
1 1 SCOP 56054 Ribosomal protein L6
1 1 SCOP 56200 Methenyltetrahydromethanopterin cyclohydrolase
1 1 SCOP 56220 DNase I-like
1 1 SCOP 56236 Class II glutamine amidotransferases
1 1 SCOP 56244 Penicillin acylase, catalytic domain
1 1 SCOP 56323 ADC synthase
1 1 SCOP 56328 Lactate & malate dehydrogenases, C-terminal domain
1 1 SCOP 56543 Substrate-binding domain of HMG-CoA reductase
1 1 SCOP 56656 Inositol monophosphatase/fructose-1,6-bisphosphatase-like
1 1 SCOP 56720 Type II DNA topoisomerase
1 1 SCOP 56727 DNA topoisomerase IV, alpha subunit
1 1 SCOP 56748 PriA-like
1 1 SCOP 56753 D-aminoacid aminotransferase-like PLP-dependent enzymes
1 1 SCOP 56763 Nickel-iron hydrogenase, large subunit
1 1 SCOP 56771 Nickel-iron hydrogenase, small subunit
1 1 SCOP 56809 Ribosomal protein L1
1 1 SCOP 56895 Aquaporin-like
1 1 SCOP 63979 ATP sulfurylase catalytic domain
1 1 SCOP 64006 Undecaprenyl diphosphate synthase
1 1 SCOP 64089 BadF/BadG/BcrA/BcrD-like
1 1 SCOP 64154 YjeF N-terminal domain-like
1 1 SCOP 64168 SurE-like
1 1 SCOP 64183 Manganese-dependent inorganic pyrophosphatase (family II)
1 1 SCOP 64372 3,4-dihydroxy-2-butanone 4-phosphate synthase, DHBP synthase, RibB
1 1 SCOP 64427 DNA double-strand break repair nuclease
1 1 SCOP 64511 Phosphoserine phosphatase
1 1 SCOP 64514 Carbon monoxide dehydrogenase
1 1 SCOP 69557 Spermidine synthase
1 1 SCOP 69599 mono-SIS domain
1 1 SCOP 69602 L-histidinol dehydrogenase HisD
1 1 SCOP 69696 SRP19
1 1 SCOP 69722 DsrC, the gamma subunit of dissimilatory sulfite reductase
1 1 SCOP 69746 Pseudouridine synthase II TruB
1 1 SCOP 69865 Argininosuccinate synthetase, C-terminal domain
1 1 SCOP 69912 Clc chloride channel
1 1 SCOP 74656 CoA transferase alpha subunit-like
1 1 SCOP 75292 YjeF C-terminal domain-like
1 1 SCOP 75297 N-acetyl-l-glutamate kinase
1 1 SCOP 75434 Divalent ion tolerance proteins CutA (CutA1)
1 1 SCOP 81656 Meta-cation ATPase, catalytic domain P
1 1 SCOP 82336 Shikimate dehydrogenase-like
1 1 SCOP 82705 DNA-binding protein AlbA
1 1 SCOP 82803 Phosphoesterase-related
1 1 SCOP 82852 Acetyl-CoA synthase
1 1 SCOP 88683 Eukaryotic ODC-like
1 1 SCOP 88698 PUA domain
1 1 SCOP 88749 Pyruvate oxidase and decarboxylase PP module
1 1 SCOP 88784 rRNA adenine dimethylase-like
1 1 SCOP 89125 Nop domain
1 1 SCOP 89494 HMGL-like
1 1 SCOP 89716 XPF/Rad1/Mus81 nuclease
1 1 SCOP 89724 Macro domain
1 1 SCOP 89751 Ta1320-like
1 1 SCOP 90217 Ribosomal protein S27e
1 1 SCOP 100948 Isochorismatase-like hydrolases
1 1 SCOP 101030 RecQ helicase DNA-binding domain-like
1 1 SCOP 101274 Archaeal tRNA CCA-adding enzyme substrate-binding domain
1 1 SCOP 101479 ADP-ribosylglycohydrolase
1 1 SCOP 101745 RNase P subunit p29-like
1 1 SCOP 101822 Aminopeptidase/glucanase lid domain
1 1 SCOP 101905 GyrA/ParC C-terminal domain-like
1 1 SCOP 101995 PA3696/SPS0176-like
1 1 SCOP 102317 NagD-like
1 1 SCOP 102325 F420-dependent methylenetetrahydromethanopterin dehydrogenase (MTD)
1 1 SCOP 102463 Peptidyl-tRNA hydrolase II
1 1 SCOP 102646 CoaB-like
1 1 SCOP 102706 NIF3 (NGG1p interacting factor 3)-like
1 1 SCOP 102713 JAB1/MPN domain
1 1 SCOP 102769 ATP-dependent protease Lon (La), catalytic domain
1 1 SCOP 102932 Catalytic subunit of bi-partite nucleotidyltransferase
1 1 SCOP 102940 Archaeal tRNA CCA-adding enzyme catalytic domain
1 1 SCOP 102995 Archaeal tRNA CCA-adding enzyme
1 1 SCOP 103166 Ta1353-like
1 1 SCOP 103257 Hypothetical protein TM0160
1 1 SCOP 103264 Chorismate synthase, AroC
1 1 SCOP 103366 Hypothetical protein PH1602
1 1 SCOP 103492 Preprotein translocase SecY subunit
1 1 SCOP 109680 TrmB-like
1 1 SCOP 109702 Rio2 serine protein kinase N-terminal domain
1 1 SCOP 109725 Conserved carboxylase domain
1 1 SCOP 109729 Hypothetical protein AF0491, middle domain
1 1 SCOP 109756 PhoU-like
1 1 SCOP 110388 MoCo biosynthesis proteins
1 1 SCOP 110436 Ornithine cyclodeaminase-like
1 1 SCOP 110616 MTH1675-like
1 1 SCOP 110640 PIWI domain
1 1 SCOP 110734 Glycosyl transferases group 1
1 1 SCOP 110742 CbiX-like
1 1 SCOP 110893 Hypothetical protein AF0491, N-terminal domain
1 1 SCOP 110976 Hypothetical protein AF0491, C-terminal domain
1 1 SCOP 111039 YjbQ-like
1 1 SCOP 111204 RIO1-like kinases
1 1 SCOP 111219 ArgJ-like
1 1 SCOP 111250 Sulfolobus fructose-1,6-bisphosphatase-like
1 1 SCOP 111322 AF1104-like
1 1 SCOP 111332 NAD kinase-like
1 1 SCOP 111343 CbiD-like
1 1 SCOP 117458 FumA C-terminal domain-like
1 1 SCOP 117638 MRR-like
1 1 SCOP 117795 Formaldehyde-activating enzyme, FAE
1 1 SCOP 118162 Tpt1/KptA
1 1 SCOP 140727 AF0941-like
1 1 SCOP 140794 AF0060-like
1 1 SCOP 141368 UbiD middle domain-like
1 1 SCOP 141519 TM1367-like
1 1 SCOP 141703 Atu2648/PH1033-like
1 1 SCOP 141735 HisI-like
1 1 SCOP 141755 PdxS-like
1 1 SCOP 141979 AF0055-like
1 1 SCOP 142040 AF1403 C-terminal domain-like
1 1 SCOP 142093 ThiI-like
1 1 SCOP 142130 ACDE2-like
1 1 SCOP 142339 CofD-like
1 1 SCOP 142536 AF0625-like
1 1 SCOP 142622 Met-10+ protein-like
1 1 SCOP 142696 RibA-like
1 1 SCOP 142701 RibD C-terminal domain-like
1 1 SCOP 142755 NadA-like
1 1 SCOP 142789 TM0189-like
1 1 SCOP 143094 AF0104-like
1 1 SCOP 143398 AF1403 N-terminal domain-like
1 1 SCOP 143448 AMMECR1-like
1 1 SCOP 143866 CorA soluble domain-like
1 1 SCOP 143916 RNase Z-like
1 1 SCOP 143969 UbiD C-terminal domain-like
1 1 SCOP 143976 lvD/EDD N-terminal domain-like
1 1 SCOP 143996 AF2331-like
1 1 SCOP 144011 CofE-like
1 1 SCOP 144028 Nqo4-like
1 1 SCOP 144031 Nq06-like
1 1 SCOP 144084 Magnesium transport protein CorA, transmembrane region
1 1 SCOP 158338 Rps19E-like
1 1 SCOP 158373 AF1782-like
1 1 SCOP 158473 HAMP domain
1 1 SCOP 158569 Cas Cmr5-like
1 1 SCOP 158706 Achaeal helicase C-terminal domain
1 1 SCOP 159154 CTP-dependent riboflavin kinase-like
1 1 SCOP 159164 MTH863-like
1 1 SCOP 159360 AF2212-like
1 1 SCOP 159447 DRTGG domain
1 1 SCOP 159464 AF0587 domain-like
1 1 SCOP 159469 AtpF-like
1 1 SCOP 159513 EMG1/NEP1-like
1 1 SCOP 159518 AF1056-like
1 1 SCOP 159523 AF0751-like
1 1 SCOP 159526 PurP N-terminal domain-like
1 1 SCOP 159537 AF1437-like
1 1 SCOP 159697 TRM1-like
1 1 SCOP 159720 mannose-1-phosphate guanylyl transferase
1 1 SCOP 159723 MM2497-like
1 1 SCOP 160053 AF0587 pre C-terminal domain-like
1 1 SCOP 160364 MTH889-like
1 1 SCOP 160415 AF1396-like
1 1 SCOP 160489 SSO1042-like
1 1 SCOP 160883 CheD-like
1 1 SCOP 160976 AF1531-like
1 1 SCOP 161071 SNF-like
1 1 SCOP 161099 MetI-like

The following families have one or more weak hits: