Family Assignments

Domains Proteins SCOP Link Families
17 11 SCOP 81268 Tandem AAA-ATPase domain
14 14 SCOP 52686 ABC transporter ATPase domain-like
12 10 SCOP 81269 Extended AAA-ATPase domain
11 11 SCOP 55682 Class II aminoacyl-tRNA synthetase (aaRS)-like, catalytic domain
9 9 SCOP 51751 Tyrosine-dependent oxidoreductases
9 9 SCOP 52375 Class I aminoacyl-tRNA synthetases (RS), catalytic domain
7 7 SCOP 52592 G proteins
6 6 SCOP 52670 RecA protein-like (ATPase-domain)
6 6 SCOP 53417 GABA-aminotransferase-like
6 6 SCOP 56802 Acetyl-CoA synthetase-like
5 5 SCOP 51446 Amylase, catalytic domain
5 5 SCOP 52318 Class I glutamine amidotransferases (GAT)
5 5 SCOP 53721 ALDH-like
4 4 SCOP 51830 Formate/glycerate dehydrogenases, NAD-domain
4 4 SCOP 52103 Crotonase-like
4 4 SCOP 52541 Nucleotide and nucleoside kinases
4 4 SCOP 52652 Nitrogenase iron protein-like
4 2 SCOP 53068 Actin/HSP70
4 4 SCOP 53402 Cystathionine synthase-like
4 4 SCOP 53851 Phosphate binding protein-like
4 2 SCOP 53902 Thiolase-related
4 4 SCOP 55921 Creatinase/aminopeptidase
4 2 SCOP 63412 MPP-like
4 2 SCOP 82867 Multidrug efflux transporter AcrB transmembrane domain
4 3 SCOP 89572 Biotin dependent carboxylase carboxyltransferase domain
3 3 SCOP 50282 Cold shock DNA-binding domain-like
3 3 SCOP 50448 Elongation factors
3 3 SCOP 52030 GroEL-like chaperone, apical domain
3 2 SCOP 52441 BC N-terminal domain-like
3 3 SCOP 52778 CAT-like
3 3 SCOP 52901 Glutathione peroxidase-like
3 3 SCOP 55879 DNA gyrase/MutL, N-terminal domain
3 1 SCOP 55974 S-adenosylmethionine synthetase
3 2 SCOP 56067 BC ATP-binding domain-like
3 3 SCOP 118216 Proton glutamate symport protein
3 3 SCOP 142721 PyrH-like
2 2 SCOP 47324 Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases
2 2 SCOP 47918 C-terminal domain of alpha and beta subunits of F1 ATP synthase
2 2 SCOP 48257 Citrate synthase
2 2 SCOP 48558 L-aspartase/fumarase
2 2 SCOP 48593 GroEL chaperone, ATPase domain
2 2 SCOP 50678 ValRS/IleRS/LeuRS editing domain
2 2 SCOP 51396 FMN-linked oxidoreductases
2 2 SCOP 51413 Inosine monophosphate dehydrogenase (IMPDH)
2 2 SCOP 51570 Class I aldolase
2 2 SCOP 51599 Class I DAHP synthetase
2 2 SCOP 51691 NadC C-terminal domain-like
2 2 SCOP 51800 Glyceraldehyde-3-phosphate dehydrogenase-like, N-terminal domain
2 2 SCOP 51868 6-phosphogluconate dehydrogenase-like, N-terminal domain
2 2 SCOP 51883 Aminoacid dehydrogenase-like, C-terminal domain
2 2 SCOP 51943 FAD/NAD-linked reductases, N-terminal and central domains
2 2 SCOP 52097 Clp protease, ClpP subunit
2 2 SCOP 52211 Succinyl-CoA synthetase domains
2 2 SCOP 52403 N-type ATP pyrophosphatases
2 2 SCOP 52769 Arginase-like amidino hydrolases
2 2 SCOP 52926 Branched-chain alpha-keto acid dehydrogenase beta-subunit, C-terminal-domain
2 1 SCOP 53089 Glycerol kinase
2 2 SCOP 53138 Ribosomal protein L18 and S11
2 2 SCOP 53687 Tryptophan synthase beta subunit-like PLP-dependent enzymes
2 2 SCOP 53811 TroA-like
2 1 SCOP 54229 Ribonuclease PH domain 1-like
2 2 SCOP 54535 FKBP immunophilin/proline isomerase
2 2 SCOP 54920 Nucleoside diphosphate kinase, NDK
2 2 SCOP 55121 Pseudouridine synthase I TruA
2 2 SCOP 55209 Enolpyruvate transferase, EPT
2 2 SCOP 55425 FAD/NAD-linked reductases, dimerisation (C-terminal) domain
2 2 SCOP 56350 Lambda integrase-like, catalytic core
2 2 SCOP 56713 Prokaryotic type I DNA topoisomerase
2 2 SCOP 56720 Type II DNA topoisomerase
2 2 SCOP 56955 Outer membrane efflux proteins (OEP)
2 2 SCOP 68901 Cytidylytransferase
2 2 SCOP 75218 SpoU-like RNA 2'-O ribose methyltransferase
2 2 SCOP 75621 Release factor
2 2 SCOP 81605 PP2C-like
2 1 SCOP 81902 HCP-like
2 2 SCOP 88704 Phosphoenolpyruvate mutase/Isocitrate lyase-like
2 2 SCOP 88741 Branched-chain alpha-keto acid dehydrogenase Pyr module
2 2 SCOP 88766 Branched-chain alpha-keto acid dehydrogenase PP module
2 2 SCOP 88854 Protein kinases, catalytic subunit
2 2 SCOP 89800 Deoxycytidylate deaminase-like
2 2 SCOP 90124 ABC transporter transmembrane region
2 2 SCOP 102406 MoCo carrier protein-like
2 2 SCOP 102769 ATP-dependent protease Lon (La), catalytic domain
2 2 SCOP 111370 HlyD-like secretion proteins
2 2 SCOP 142635 hypothetical RNA methyltransferase
2 2 SCOP 142678 Glycine dehydrogenase subunits (GDC-P)
2 2 SCOP 161071 SNF-like
1 1 SCOP 46463 Globins
1 1 SCOP 46566 Chaperone J-domain
1 1 SCOP 46610 Fe,Mn superoxide dismutase (SOD), N-terminal domain
1 1 SCOP 46947 Ribosomal protein S13
1 1 SCOP 47253 Ribonucleotide reductase-like
1 1 SCOP 47786 NAD+-dependent DNA ligase, domain 3
1 1 SCOP 47974 Ribosomal protein S7
1 1 SCOP 48151 Endonuclease III
1 1 SCOP 48154 Mismatch glycosylase
1 1 SCOP 48180 Hydroxyisobutyrate and 6-phosphogluconate dehydrogenase domain
1 1 SCOP 48335 DNA repair protein MutS, domain III
1 1 SCOP 48572 HAL/PAL-like
1 1 SCOP 48577 Isoprenyl diphosphate synthases
1 1 SCOP 49330 Cu,Zn superoxide dismutase-like
1 1 SCOP 49541 Periplasmic domain of cytochrome c oxidase subunit II
1 1 SCOP 50114 C-terminal domain of ribosomal protein L2
1 1 SCOP 50136 Alcohol dehydrogenase-like, N-terminal domain
1 1 SCOP 50194 Ribosomal protein L14
1 1 SCOP 50250 Anticodon-binding domain
1 1 SCOP 50277 Myf domain
1 1 SCOP 50325 Inorganic pyrophosphatase
1 1 SCOP 50461 Ribosomal protein L3
1 1 SCOP 50466 EF-Tu/eEF-1alpha/eIF2-gamma C-terminal domain
1 1 SCOP 50495 Prokaryotic proteases
1 1 SCOP 50892 Cyclophilin (peptidylprolyl isomerase)
1 1 SCOP 51162 UDP N-acetylglucosamine acyltransferase
1 1 SCOP 51183 dTDP-sugar isomerase
1 1 SCOP 51231 Biotinyl/lipoyl-carrier proteins and domains
1 1 SCOP 51247 BC C-terminal domain-like
1 1 SCOP 51284 dUTPase-like
1 1 SCOP 51352 Triosephosphate isomerase (TIM)
1 1 SCOP 51372 D-ribulose-5-phosphate 3-epimerase
1 1 SCOP 51375 Decarboxylase
1 1 SCOP 51420 Alanine racemase-like, N-terminal domain
1 1 SCOP 51431 Aldo-keto reductases (NADP)
1 1 SCOP 51594 5-aminolaevulinate dehydratase, ALAD (porphobilinogen synthase)
1 1 SCOP 51605 Enolase
1 1 SCOP 51622 Pyruvate kinase
1 1 SCOP 51659 Endonuclease IV
1 1 SCOP 51704 Methylmalonyl-CoA mutase, N-terminal (CoA-binding) domain
1 1 SCOP 51714 tRNA-guanine transglycosylase
1 1 SCOP 51718 Dihydropteroate synthetase
1 1 SCOP 51727 Uroporphyrinogen decarboxylase, UROD
1 1 SCOP 51736 Alcohol dehydrogenase-like, C-terminal domain
1 1 SCOP 51848 LDH N-terminal domain-like
1 1 SCOP 51900 CoA-binding domain
1 1 SCOP 52002 R1 subunit of ribonucleotide reductase, C-terminal domain
1 1 SCOP 52017 LeuD-like
1 1 SCOP 52122 Lumazine synthase
1 1 SCOP 52142 Uracil-DNA glycosylase
1 1 SCOP 52152 FabD-like
1 1 SCOP 52162 Ribosomal protein L13
1 1 SCOP 52167 Ribosomal protein L4
1 1 SCOP 52173 CheY-related
1 1 SCOP 52284 Formate/glycerate dehydrogenases, substrate-binding domain
1 1 SCOP 52297 L-alanine dehydrogenase-like
1 1 SCOP 52300 S-adenosylhomocystein hydrolase
1 1 SCOP 52314 Ribosomal protein S2
1 1 SCOP 52484 Transhydrogenase domain III (dIII)
1 1 SCOP 52584 Phosphoribulokinase/pantothenate kinase
1 1 SCOP 52744 Subtilases
1 1 SCOP 52773 Histone deacetylase, HDAC
1 1 SCOP 52923 Transketolase C-terminal domain-like
1 1 SCOP 52944 ATP synthase (F1-ATPase), gamma subunit
1 1 SCOP 52973 ITPase (Ham1)
1 1 SCOP 52976 Maf-like
1 1 SCOP 53045 5' to 3' exonuclease catalytic domain
1 1 SCOP 53099 Ribonuclease H
1 1 SCOP 53118 DnaQ-like 3'-5' exonuclease
1 1 SCOP 53134 RuvC resolvase
1 1 SCOP 53168 Purine and uridine phosphorylases
1 1 SCOP 53179 Peptidyl-tRNA hydrolase-like
1 1 SCOP 53201 Leucine aminopeptidase, C-terminal domain
1 1 SCOP 53224 Aminoacid dehydrogenases
1 1 SCOP 53235 Tetrahydrofolate dehydrogenase/cyclohydrolase
1 1 SCOP 53245 MurCDEF C-terminal domain
1 1 SCOP 53255 Cofactor-dependent phosphoglycerate mutase
1 1 SCOP 53296 Phosphoribosylpyrophosphate synthetase-like
1 1 SCOP 53329 Formyltransferase
1 1 SCOP 53354 Protein-L-isoaspartyl O-methyltransferase
1 1 SCOP 53384 AAT-like
1 1 SCOP 53461 UDP-glucose pyrophosphorylase
1 1 SCOP 53629 Folylpolyglutamate synthetase
1 1 SCOP 53660 Dimeric isocitrate & isopropylmalate dehydrogenases
1 1 SCOP 53672 Aspartate/ornithine carbamoyltransferase
1 1 SCOP 53682 Aspartate/glutamate racemase
1 1 SCOP 53698 double-SIS domain
1 1 SCOP 53701 Phosphoglucose isomerase, PGI
1 1 SCOP 53733 Aconitase iron-sulfur domain
1 1 SCOP 53749 Phosphoglycerate kinase
1 1 SCOP 53760 Peptidoglycan biosynthesis glycosyltransferase MurG
1 1 SCOP 53785 Phosphofructokinase
1 1 SCOP 53791 Tetrapyrrole methylase
1 1 SCOP 53796 PEP carboxykinase C-terminal domain
1 1 SCOP 53801 Ferrochelatase
1 1 SCOP 53914 Chalcone synthase-like
1 1 SCOP 54212 Translational machinery components
1 1 SCOP 54224 DNA gyrase/MutL, second domain
1 1 SCOP 54232 GHMP Kinase, N-terminal domain
1 1 SCOP 54571 Ribosomal protein S19
1 1 SCOP 54714 Elongation factor Ts (EF-Ts), dimerisation domain
1 1 SCOP 54720 Fe,Mn superoxide dismutase (SOD), C-terminal domain
1 1 SCOP 54748 Ribosomal L11/L12e N-terminal domain
1 1 SCOP 54811 GMP synthetase C-terminal dimerisation domain
1 1 SCOP 54815 Prokaryotic type KH domain (KH-domain type II)
1 1 SCOP 54822 Ribosomal protein S3 C-terminal domain
1 1 SCOP 54827 Enolase N-terminal domain-like
1 1 SCOP 54844 Ribosomal protein L22
1 1 SCOP 54981 EF-G/eEF-2 domains III and V
1 1 SCOP 55000 Ribosomal protein S10
1 1 SCOP 55069 Peptide methionine sulfoxide reductase
1 1 SCOP 55178 Ribosomal protein S4
1 1 SCOP 55187 Threonyl-tRNA synthetase (ThrRS), second 'additional' domain
1 1 SCOP 55195 Ribosome recycling factor, RRF
1 1 SCOP 55201 Translation initiation factor IF3, C-terminal domain
1 1 SCOP 55272 DNA repair protein MutS, domain I
1 1 SCOP 55283 Ribosomal protein L5
1 1 SCOP 55299 YjgF/L-PSP
1 1 SCOP 55348 GAPDH-like
1 1 SCOP 55376 Glucose 6-phosphate dehydrogenase-like
1 1 SCOP 55490 Thermolysin-like
1 1 SCOP 55502 Neutral endopeptidase (neprilysin)
1 1 SCOP 55505 Neurolysin-like
1 1 SCOP 55621 GTP cyclohydrolase I
1 1 SCOP 55667 Ribonuclease PH domain 2-like
1 1 SCOP 55875 Heat shock protein 90, HSP90, N-terminal domain
1 1 SCOP 56038 B3/B4 domain of PheRS, PheT
1 1 SCOP 56048 Ribosomal protein S8
1 1 SCOP 56054 Ribosomal protein L6
1 1 SCOP 56081 Succinyl-CoA synthetase, beta-chain, N-terminal domain
1 1 SCOP 56096 Adenylation domain of NAD+-dependent DNA ligase
1 1 SCOP 56236 Class II glutamine amidotransferases
1 1 SCOP 56323 ADC synthase
1 1 SCOP 56328 Lactate & malate dehydrogenases, C-terminal domain
1 1 SCOP 56421 Peptide deformylase
1 1 SCOP 56543 Substrate-binding domain of HMG-CoA reductase
1 1 SCOP 56635 Heme-dependent catalases
1 1 SCOP 56646 Medium chain acyl-CoA dehydrogenase, NM (N-terminal and middle) domains
1 1 SCOP 56656 Inositol monophosphatase/fructose-1,6-bisphosphatase-like
1 1 SCOP 56673 DNA polymerase I
1 1 SCOP 56732 DNA primase DnaG catalytic core
1 1 SCOP 56797 Dehydroquinate synthase, DHQS
1 1 SCOP 56809 Ribosomal protein L1
1 1 SCOP 63381 Ferredoxin reductase FAD-binding domain-like
1 1 SCOP 63588 Glycosyltransferase family 36 C-terminal domain
1 1 SCOP 63783 Riboflavin synthase
1 1 SCOP 63971 Inosicase
1 1 SCOP 64006 Undecaprenyl diphosphate synthase
1 1 SCOP 64154 YjeF N-terminal domain-like
1 1 SCOP 64168 SurE-like
1 1 SCOP 64186 HPr kinase HprK C-terminal domain
1 1 SCOP 64198 AICAR transformylase domain of bifunctional purine biosynthesis enzyme ATIC
1 1 SCOP 64264 Prokaryotic ribosomal protein L17
1 1 SCOP 64372 3,4-dihydroxy-2-butanone 4-phosphate synthase, DHBP synthase, RibB
1 1 SCOP 64485 RNA-polymerase beta
1 1 SCOP 64490 RNA-polymerase beta-prime
1 1 SCOP 68924 PEP carboxykinase N-terminal domain
1 1 SCOP 69222 PepX C-terminal domain-like
1 1 SCOP 69501 DTD-like
1 1 SCOP 69594 Glycerol-3-phosphate (1)-acyltransferase
1 1 SCOP 69599 mono-SIS domain
1 1 SCOP 69706 Transcription factor NusA, N-terminal domain
1 1 SCOP 69746 Pseudouridine synthase II TruB
1 1 SCOP 69892 Iron-containing alcohol dehydrogenase
1 1 SCOP 74732 Ribosomal protein L20
1 1 SCOP 74756 3-Methyladenine DNA glycosylase I (Tag)
1 1 SCOP 74983 Small protein B (SmpB)
1 1 SCOP 75073 Hydantoinase (dihydropyrimidinase), catalytic domain
1 1 SCOP 75131 B12-dependent (class II) ribonucleotide reductase
1 1 SCOP 75292 YjeF C-terminal domain-like
1 1 SCOP 75305 Amidase signature (AS) enzymes
1 1 SCOP 75323 Exonuclease RecJ
1 1 SCOP 75459 Pseudouridine synthase RsuA/RluD
1 1 SCOP 75626 YebC-like
1 1 SCOP 75648 ABC transporter involved in vitamin B12 uptake, BtuC
1 1 SCOP 81441 Cytochrome c oxidase subunit I-like
1 1 SCOP 81451 Cytochrome c oxidase subunit III-like
1 1 SCOP 81642 Cytochrome b of cytochrome bc1 complex (Ubiquinol-cytochrome c reductase)
1 1 SCOP 81887 Helical scaffold and wing domains of SecA
1 1 SCOP 82052 Obg GTP-binding protein N-terminal domain
1 1 SCOP 82267 TatD Mg-dependent DNase-like
1 1 SCOP 82540 Trehalose-6-phosphate synthase, OtsA
1 1 SCOP 82583 G domain-linked domain
1 1 SCOP 82661 Poly A polymerase head domain-like
1 1 SCOP 88735 TK-like Pyr module
1 1 SCOP 88760 TK-like PP module
1 1 SCOP 88784 rRNA adenine dimethylase-like
1 1 SCOP 88786 C5 cytosine-specific DNA methylase, DCM
1 1 SCOP 88947 Sigma2 domain of RNA polymerase sigma factors
1 1 SCOP 89032 Cobalamin adenosyltransferase
1 1 SCOP 89416 gamma-Butyrobetaine hydroxylase
1 1 SCOP 89629 tRNA(m1G37)-methyltransferase TrmD
1 1 SCOP 89724 Macro domain
1 1 SCOP 89784 ADP-heptose LPS heptosyltransferase II
1 1 SCOP 89902 PaaI/YdiI-like
1 1 SCOP 100921 Heat shock protein 70kD (HSP70), peptide-binding domain
1 1 SCOP 100948 Isochorismatase-like hydrolases
1 1 SCOP 101354 Putative anticodon-binding domain of alanyl-tRNA synthetase (AlaRS)
1 1 SCOP 101905 GyrA/ParC C-terminal domain-like
1 1 SCOP 101961 Stabilizer of iron transporter SufD
1 1 SCOP 102517 N-acetylmuramoyl-L-alanine amidase-like
1 1 SCOP 102575 NOL1/NOP2/sun
1 1 SCOP 102589 LmbE-like
1 1 SCOP 102660 PlsX-like
1 1 SCOP 102706 NIF3 (NGG1p interacting factor 3)-like
1 1 SCOP 102755 Hsp90 middle domain
1 1 SCOP 102887 Coproporphyrinogen III oxidase
1 1 SCOP 103026 Aminomethyltransferase folate-binding domain
1 1 SCOP 103264 Chorismate synthase, AroC
1 1 SCOP 103366 Hypothetical protein PH1602
1 1 SCOP 103379 2-methylcitrate dehydratase PrpD
1 1 SCOP 103474 Glycerol-3-phosphate transporter
1 1 SCOP 110148 MdoG-like
1 1 SCOP 110368 NeuB-like
1 1 SCOP 110739 Glycerate kinase I
1 1 SCOP 111305 Recombination protein RecR
1 1 SCOP 111327 Urocanase
1 1 SCOP 111332 NAD kinase-like
1 1 SCOP 111338 QueA-like
1 1 SCOP 117397 TM1631-like
1 1 SCOP 117558 Type II thymidine kinase
1 1 SCOP 117583 Myo-inositol hexaphosphate phosphohydrolase (phytase) PhyA
1 1 SCOP 117619 Exodeoxyribonuclease V beta chain (RecB), C-terminal domain
1 1 SCOP 117888 Ribosomal protein L16p
1 1 SCOP 140479 LemA-like
1 1 SCOP 140991 FtsH protease domain-like
1 1 SCOP 141190 PhnA-like
1 1 SCOP 141245 Ribosomal protein L19
1 1 SCOP 141703 Atu2648/PH1033-like
1 1 SCOP 141755 PdxS-like
1 1 SCOP 142696 RibA-like
1 1 SCOP 143549 Serine dehydratase beta chain-like
1 1 SCOP 143598 YojJ-like
1 1 SCOP 143717 AstA-like
1 1 SCOP 143809 Succinylarginine dihydrolase-like
1 1 SCOP 143812 GatB/GatE catalytic domain-like
1 1 SCOP 143916 RNase Z-like
1 1 SCOP 143927 beta-CASP RNA-metabolising hydrolases
1 1 SCOP 143959 Sulfatase-modifying factor-like
1 1 SCOP 144053 Thermophilic metalloprotease (M29)
1 1 SCOP 158600 MgsA/YrvN C-terminal domain-like
1 1 SCOP 158833 Tex N-terminal region-like
1 1 SCOP 159112 RNB domain-like
1 1 SCOP 159400 Imidazolonepropionase-like
1 1 SCOP 159635 Tex RuvX-like domain-like
1 1 SCOP 159720 mannose-1-phosphate guanylyl transferase
1 1 SCOP 161094 MgtE membrane domain-like

The following families have one or more weak hits: