Family Assignments

Domains Proteins SCOP Link Families
40 38 SCOP 52686 ABC transporter ATPase domain-like
14 9 SCOP 81268 Tandem AAA-ATPase domain
13 13 SCOP 53851 Phosphate binding protein-like
13 10 SCOP 81269 Extended AAA-ATPase domain
10 10 SCOP 52375 Class I aminoacyl-tRNA synthetases (RS), catalytic domain
9 9 SCOP 51751 Tyrosine-dependent oxidoreductases
8 8 SCOP 55682 Class II aminoacyl-tRNA synthetase (aaRS)-like, catalytic domain
6 6 SCOP 51883 Aminoacid dehydrogenase-like, C-terminal domain
6 6 SCOP 52318 Class I glutamine amidotransferases (GAT)
6 6 SCOP 52592 G proteins
6 6 SCOP 52652 Nitrogenase iron protein-like
6 6 SCOP 53384 AAT-like
5 5 SCOP 51396 FMN-linked oxidoreductases
5 5 SCOP 52403 N-type ATP pyrophosphatases
5 5 SCOP 53402 Cystathionine synthase-like
5 5 SCOP 53417 GABA-aminotransferase-like
5 5 SCOP 81656 Meta-cation ATPase, catalytic domain P
4 4 SCOP 50282 Cold shock DNA-binding domain-like
4 4 SCOP 51570 Class I aldolase
4 2 SCOP 53068 Actin/HSP70
4 4 SCOP 53721 ALDH-like
4 4 SCOP 53816 Nitrogenase iron-molybdenum protein
4 3 SCOP 56067 BC ATP-binding domain-like
4 4 SCOP 101768 TRAM domain
3 3 SCOP 48311 Aldehyde ferredoxin oxidoreductase, C-terminal domains
3 3 SCOP 48596 Group II chaperonin (CCT, TRIC), ATPase domain
3 2 SCOP 49300 PKD domain
3 3 SCOP 50448 Elongation factors
3 3 SCOP 51868 6-phosphogluconate dehydrogenase-like, N-terminal domain
3 3 SCOP 52017 LeuD-like
3 3 SCOP 52034 Group II chaperonin (CCT, TRIC), apical domain
3 2 SCOP 52441 BC N-terminal domain-like
3 3 SCOP 52670 RecA protein-like (ATPase-domain)
3 3 SCOP 53660 Dimeric isocitrate & isopropylmalate dehydrogenases
3 3 SCOP 53687 Tryptophan synthase beta subunit-like PLP-dependent enzymes
3 3 SCOP 53733 Aconitase iron-sulfur domain
3 3 SCOP 53791 Tetrapyrrole methylase
3 3 SCOP 54535 FKBP immunophilin/proline isomerase
3 3 SCOP 55327 PurM N-terminal domain-like
3 3 SCOP 56043 PurM C-terminal domain-like
3 3 SCOP 56229 Aldehyde ferredoxin oxidoreductase, N-terminal domain
3 3 SCOP 56763 Nickel-iron hydrogenase, large subunit
3 3 SCOP 56771 Nickel-iron hydrogenase, small subunit
3 3 SCOP 56802 Acetyl-CoA synthetase-like
3 3 SCOP 58105 Methyl-accepting chemotaxis protein (MCP) signaling domain
3 3 SCOP 75099 Monomethylamine methyltransferase MtmB
3 3 SCOP 88724 Pyruvate oxidase and decarboxylase Pyr module
3 3 SCOP 101984 Pirin-like
3 3 SCOP 109756 PhoU-like
3 3 SCOP 142606 N-6 DNA Methylase-like
3 3 SCOP 142721 PyrH-like
3 3 SCOP 144028 Nqo4-like
3 3 SCOP 160804 PurP ATP-binding domain-like
2 2 SCOP 47241 Ferritin
2 2 SCOP 47324 Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases
2 2 SCOP 48082 Methyl-coenzyme M reductase alpha and beta chain C-terminal domain
2 2 SCOP 48558 L-aspartase/fumarase
2 2 SCOP 50466 EF-Tu/eEF-1alpha/eIF2-gamma C-terminal domain
2 2 SCOP 51174 gamma-carbonic anhydrase-like
2 2 SCOP 51367 Histidine biosynthesis enzymes
2 2 SCOP 51381 Tryptophan biosynthesis enzymes
2 2 SCOP 51687 F420 dependent oxidoreductases
2 2 SCOP 51800 Glyceraldehyde-3-phosphate dehydrogenase-like, N-terminal domain
2 2 SCOP 51830 Formate/glycerate dehydrogenases, NAD-domain
2 2 SCOP 52081 Ribosomal proteins L15p and L18e
2 2 SCOP 52256 N5-CAIR mutase (phosphoribosylaminoimidazole carboxylase, PurE)
2 2 SCOP 52419 Nucleoside phosphorylase/phosphoribosyltransferase catalytic domain
2 2 SCOP 52468 Deoxyhypusine synthase, DHS
2 2 SCOP 52491 Tubulin, GTPase domain
2 2 SCOP 52739 Methylesterase CheB, C-terminal domain
2 2 SCOP 52955 Anticodon-binding domain of Class II aaRS
2 1 SCOP 53080 Acetokinase-like
2 2 SCOP 53204 Bacterial dinuclear zinc exopeptidases
2 2 SCOP 53272 Phosphoribosyltransferases (PRTases)
2 2 SCOP 53620 Thiamin biosynthesis kinases
2 2 SCOP 53672 Aspartate/ornithine carbamoyltransferase
2 2 SCOP 53707 Formate dehydrogenase/DMSO reductase, domains 1-3
2 2 SCOP 54224 DNA gyrase/MutL, second domain
2 2 SCOP 54229 Ribonuclease PH domain 1-like
2 2 SCOP 54914 Prokaryotic signal transducing protein
2 2 SCOP 55094 Methyl-coenzyme M reductase alpha and beta chain N-terminal domain
2 1 SCOP 55113 Formylmethanofuran:tetrahydromethanopterin formyltransferase
2 2 SCOP 55308 Tubulin, C-terminal domain
2 2 SCOP 55348 GAPDH-like
2 2 SCOP 55879 DNA gyrase/MutL, N-terminal domain
2 2 SCOP 55884 Histidine kinase
2 2 SCOP 55921 Creatinase/aminopeptidase
2 2 SCOP 55932 Glutamine synthetase catalytic domain
2 2 SCOP 55946 TATA-box binding protein (TBP), C-terminal domain
2 2 SCOP 56236 Class II glutamine amidotransferases
2 2 SCOP 56251 Proteasome subunits
2 2 SCOP 56635 Heme-dependent catalases
2 2 SCOP 56713 Prokaryotic type I DNA topoisomerase
2 2 SCOP 63883 MoeA N-terminal region -like
2 2 SCOP 64147 ADP-specific Phosphofructokinase/Glucokinase
2 2 SCOP 64485 RNA-polymerase beta
2 2 SCOP 64490 RNA-polymerase beta-prime
2 2 SCOP 64514 Carbon monoxide dehydrogenase
2 2 SCOP 81664 Calcium ATPase, transmembrane domain M
2 2 SCOP 82852 Acetyl-CoA synthase
2 2 SCOP 88749 Pyruvate oxidase and decarboxylase PP module
2 2 SCOP 100888 Lesion bypass DNA polymerase (Y-family), catalytic domain
2 2 SCOP 100921 Heat shock protein 70kD (HSP70), peptide-binding domain
2 2 SCOP 102769 ATP-dependent protease Lon (La), catalytic domain
2 2 SCOP 102876 Chromosomal protein MC1
2 2 SCOP 102928 NifU/IscU domain
2 2 SCOP 110284 TM1225-like predicted glycosylases
2 2 SCOP 110513 IF2B-like
2 2 SCOP 111284 Putative modulator of DNA gyrase, PmbA/TldD
2 2 SCOP 111353 Ammonium transporter
2 2 SCOP 143423 Transposase IS200-like
2 2 SCOP 143812 GatB/GatE catalytic domain-like
2 1 SCOP 143860 Polyphosphate kinase C-terminal domain
2 2 SCOP 143927 beta-CASP RNA-metabolising hydrolases
2 2 SCOP 143979 Type I restriction modification DNA specificity domain
2 2 SCOP 144011 CofE-like
2 2 SCOP 161099 MetI-like
1 1 SCOP 46566 Chaperone J-domain
1 1 SCOP 46580 Prefoldin
1 1 SCOP 46610 Fe,Mn superoxide dismutase (SOD), N-terminal domain
1 1 SCOP 47808 5' to 3' exonuclease, C-terminal subdomain
1 1 SCOP 47965 Transcription factor IIB (TFIIB), core domain
1 1 SCOP 47974 Ribosomal protein S7
1 1 SCOP 48109 Carbamoyl phosphate synthetase, large subunit connection domain
1 1 SCOP 48141 Ribosomal protein L19 (L19e)
1 1 SCOP 48151 Endonuclease III
1 1 SCOP 48154 Mismatch glycosylase
1 1 SCOP 48184 Acetohydroxy acid isomeroreductase (ketol-acid reductoisomerase, KARI)
1 1 SCOP 48257 Citrate synthase
1 1 SCOP 48335 DNA repair protein MutS, domain III
1 1 SCOP 48404 Ankyrin repeat
1 1 SCOP 48577 Isoprenyl diphosphate synthases
1 1 SCOP 48593 GroEL chaperone, ATPase domain
1 1 SCOP 50114 C-terminal domain of ribosomal protein L2
1 1 SCOP 50136 Alcohol dehydrogenase-like, N-terminal domain
1 1 SCOP 50194 Ribosomal protein L14
1 1 SCOP 50277 Myf domain
1 1 SCOP 50307 DNA ligase/mRNA capping enzyme postcatalytic domain
1 1 SCOP 50325 Inorganic pyrophosphatase
1 1 SCOP 50342 CheW-like
1 1 SCOP 50461 Ribosomal protein L3
1 1 SCOP 50476 PNP-oxidase like
1 1 SCOP 50678 ValRS/IleRS/LeuRS editing domain
1 1 SCOP 50892 Cyclophilin (peptidylprolyl isomerase)
1 1 SCOP 51168 Galactoside acetyltransferase-like
1 1 SCOP 51183 dTDP-sugar isomerase
1 1 SCOP 51247 BC C-terminal domain-like
1 1 SCOP 51352 Triosephosphate isomerase (TIM)
1 1 SCOP 51375 Decarboxylase
1 1 SCOP 51392 Thiamin phosphate synthase
1 1 SCOP 51420 Alanine racemase-like, N-terminal domain
1 1 SCOP 51594 5-aminolaevulinate dehydratase, ALAD (porphobilinogen synthase)
1 1 SCOP 51605 Enolase
1 1 SCOP 51622 Pyruvate kinase
1 1 SCOP 51629 Pyruvate phosphate dikinase, C-terminal domain
1 1 SCOP 51650 RuBisCo, large subunit, C-terminal domain
1 1 SCOP 51691 NadC C-terminal domain-like
1 1 SCOP 51714 tRNA-guanine transglycosylase
1 1 SCOP 51718 Dihydropteroate synthetase
1 1 SCOP 51848 LDH N-terminal domain-like
1 1 SCOP 52022 Carbamoyl phosphate synthetase, small subunit N-terminal domain
1 1 SCOP 52030 GroEL-like chaperone, apical domain
1 1 SCOP 52043 Ribosomal protein L32e
1 1 SCOP 52147 Mug-like
1 1 SCOP 52157 Initiation factor IF2/eIF5b, domain 3
1 1 SCOP 52162 Ribosomal protein L13
1 1 SCOP 52167 Ribosomal protein L4
1 1 SCOP 52173 CheY-related
1 1 SCOP 52211 Succinyl-CoA synthetase domains
1 1 SCOP 52235 Quinone reductase
1 1 SCOP 52300 S-adenosylhomocystein hydrolase
1 1 SCOP 52314 Ribosomal protein S2
1 1 SCOP 52325 DJ-1/PfpI
1 1 SCOP 52397 Adenylyltransferase
1 1 SCOP 52475 Pyruvate oxidase and decarboxylase, middle domain
1 1 SCOP 52508 Homo-oligomeric flavin-containing Cys decarboxylases, HFCD
1 1 SCOP 52541 Nucleotide and nucleoside kinases
1 1 SCOP 52744 Subtilases
1 1 SCOP 52769 Arginase-like amidino hydrolases
1 1 SCOP 52773 Histone deacetylase, HDAC
1 1 SCOP 52778 CAT-like
1 1 SCOP 52789 Low-molecular-weight phosphotyrosine protein phosphatases
1 1 SCOP 52901 Glutathione peroxidase-like
1 1 SCOP 52973 ITPase (Ham1)
1 1 SCOP 52976 Maf-like
1 1 SCOP 53045 5' to 3' exonuclease catalytic domain
1 1 SCOP 53099 Ribonuclease H
1 1 SCOP 53138 Ribosomal protein L18 and S11
1 1 SCOP 53168 Purine and uridine phosphorylases
1 1 SCOP 53224 Aminoacid dehydrogenases
1 1 SCOP 53240 Malic enzyme N-domain
1 1 SCOP 53329 Formyltransferase
1 1 SCOP 53339 RNA methyltransferase FtsJ
1 1 SCOP 53342 Fibrillarin homologue
1 1 SCOP 53354 Protein-L-isoaspartyl O-methyltransferase
1 1 SCOP 53464 glucose-1-phosphate thymidylyltransferase
1 1 SCOP 53650 Alkaline phosphatase
1 1 SCOP 53653 Arylsulfatase
1 1 SCOP 53698 double-SIS domain
1 1 SCOP 53749 Phosphoglycerate kinase
1 1 SCOP 53763 UDP-N-acetylglucosamine 2-epimerase
1 1 SCOP 53766 Oligosaccharide phosphorylase
1 1 SCOP 53775 Glutaminase/Asparaginase
1 1 SCOP 53811 TroA-like
1 1 SCOP 54193 L15e
1 1 SCOP 54212 Translational machinery components
1 1 SCOP 54638 4HBT-like
1 1 SCOP 54687 Ribosomal protein L10e
1 1 SCOP 54720 Fe,Mn superoxide dismutase (SOD), C-terminal domain
1 1 SCOP 54811 GMP synthetase C-terminal dimerisation domain
1 1 SCOP 54827 Enolase N-terminal domain-like
1 1 SCOP 54844 Ribosomal protein L22
1 1 SCOP 54920 Nucleoside diphosphate kinase, NDK
1 1 SCOP 54967 Ribulose 1,5-bisphosphate carboxylase-oxygenase
1 1 SCOP 54985 eEF-1beta-like
1 1 SCOP 55041 Molybdenum cofactor biosynthesis protein C, MoaC
1 1 SCOP 55069 Peptide methionine sulfoxide reductase
1 1 SCOP 55089 Methyl-coenzyme M reductase gamma chain
1 1 SCOP 55121 Pseudouridine synthase I TruA
1 1 SCOP 55130 Ribosomal protein L30p/L7e
1 1 SCOP 55206 RNA 3'-terminal phosphate cyclase, RPTC
1 1 SCOP 55209 Enolpyruvate transferase, EPT
1 1 SCOP 55262 GAD domain
1 1 SCOP 55272 DNA repair protein MutS, domain I
1 1 SCOP 55283 Ribosomal protein L5
1 1 SCOP 55316 L30e/L7ae ribosomal proteins
1 1 SCOP 55368 Dihydrodipicolinate reductase-like
1 1 SCOP 55707 Biotin holoenzyme synthetase
1 1 SCOP 55822 YrdC-like
1 1 SCOP 55910 Ribosome anti-association factor eIF6 (aIF6)
1 1 SCOP 56048 Ribosomal protein S8
1 1 SCOP 56054 Ribosomal protein L6
1 1 SCOP 56085 Pyruvate phosphate dikinase, N-terminal domain
1 1 SCOP 56092 ATP-dependent DNA ligase catalytic domain
1 1 SCOP 56105 SAICAR synthase
1 1 SCOP 56200 Methenyltetrahydromethanopterin cyclohydrolase
1 1 SCOP 56220 DNase I-like
1 1 SCOP 56291 ROO N-terminal domain-like
1 1 SCOP 56310 Protein serine/threonine phosphatase
1 1 SCOP 56323 ADC synthase
1 1 SCOP 56328 Lactate & malate dehydrogenases, C-terminal domain
1 1 SCOP 56530 FAH
1 1 SCOP 56543 Substrate-binding domain of HMG-CoA reductase
1 1 SCOP 56575 Serpins
1 1 SCOP 56656 Inositol monophosphatase/fructose-1,6-bisphosphatase-like
1 1 SCOP 56673 DNA polymerase I
1 1 SCOP 56720 Type II DNA topoisomerase
1 1 SCOP 56727 DNA topoisomerase IV, alpha subunit
1 1 SCOP 56748 PriA-like
1 1 SCOP 56753 D-aminoacid aminotransferase-like PLP-dependent enzymes
1 1 SCOP 56809 Ribosomal protein L1
1 1 SCOP 56822 Hybrid cluster protein (prismane protein)
1 1 SCOP 63966 Precorrin-8X methylmutase CbiC/CobH
1 1 SCOP 63971 Inosicase
1 1 SCOP 64006 Undecaprenyl diphosphate synthase
1 1 SCOP 64154 YjeF N-terminal domain-like
1 1 SCOP 64159 2,3-Bisphosphoglycerate-independent phosphoglycerate mutase, substrate-binding domain
1 1 SCOP 64162 2,3-Bisphosphoglycerate-independent phosphoglycerate mutase, catalytic domain
1 1 SCOP 64168 SurE-like
1 1 SCOP 64198 AICAR transformylase domain of bifunctional purine biosynthesis enzyme ATIC
1 1 SCOP 64372 3,4-dihydroxy-2-butanone 4-phosphate synthase, DHBP synthase, RibB
1 1 SCOP 64511 Phosphoserine phosphatase
1 1 SCOP 69026 Hypothetical protein MTH865
1 1 SCOP 69599 mono-SIS domain
1 1 SCOP 69602 L-histidinol dehydrogenase HisD
1 1 SCOP 69746 Pseudouridine synthase II TruB
1 1 SCOP 69820 MTH1598-like
1 1 SCOP 69865 Argininosuccinate synthetase, C-terminal domain
1 1 SCOP 69892 Iron-containing alcohol dehydrogenase
1 1 SCOP 69912 Clc chloride channel
1 1 SCOP 75073 Hydantoinase (dihydropyrimidinase), catalytic domain
1 1 SCOP 75182 Hypothetical protein MTH777 (MT0777)
1 1 SCOP 75292 YjeF C-terminal domain-like
1 1 SCOP 75297 N-acetyl-l-glutamate kinase
1 1 SCOP 75305 Amidase signature (AS) enzymes
1 1 SCOP 75554 Smc hinge domain
1 1 SCOP 75648 ABC transporter involved in vitamin B12 uptake, BtuC
1 1 SCOP 82258 SAH/MTA deaminase-like
1 1 SCOP 82267 TatD Mg-dependent DNase-like
1 1 SCOP 88683 Eukaryotic ODC-like
1 1 SCOP 88784 rRNA adenine dimethylase-like
1 1 SCOP 89125 Nop domain
1 1 SCOP 89332 DNA replication initiator (cdc21/cdc54) N-terminal domain
1 1 SCOP 89494 HMGL-like
1 1 SCOP 89716 XPF/Rad1/Mus81 nuclease
1 1 SCOP 89724 Macro domain
1 1 SCOP 89800 Deoxycytidylate deaminase-like
1 1 SCOP 90087 GlpX-like bacterial fructose-1,6-bisphosphatase
1 1 SCOP 101274 Archaeal tRNA CCA-adding enzyme substrate-binding domain
1 1 SCOP 101340 HD domain
1 1 SCOP 101479 ADP-ribosylglycohydrolase
1 1 SCOP 101822 Aminopeptidase/glucanase lid domain
1 1 SCOP 101905 GyrA/ParC C-terminal domain-like
1 1 SCOP 101995 PA3696/SPS0176-like
1 1 SCOP 102199 Putative cyclase
1 1 SCOP 102325 F420-dependent methylenetetrahydromethanopterin dehydrogenase (MTD)
1 1 SCOP 102463 Peptidyl-tRNA hydrolase II
1 1 SCOP 102663 Phosphotransacetylase
1 1 SCOP 102706 NIF3 (NGG1p interacting factor 3)-like
1 1 SCOP 103264 Chorismate synthase, AroC
1 1 SCOP 103366 Hypothetical protein PH1602
1 1 SCOP 103492 Preprotein translocase SecY subunit
1 1 SCOP 109725 Conserved carboxylase domain
1 1 SCOP 109729 Hypothetical protein AF0491, middle domain
1 1 SCOP 110436 Ornithine cyclodeaminase-like
1 1 SCOP 110616 MTH1675-like
1 1 SCOP 110671 UbiE/COQ5-like
1 1 SCOP 110883 3-demethylubiquinone-9 3-methyltransferase
1 1 SCOP 110910 Monomeric nicotinate phosphoribosyltransferase C-terminal domain
1 1 SCOP 111039 YjbQ-like
1 1 SCOP 111168 AHSA1 domain
1 1 SCOP 111219 ArgJ-like
1 1 SCOP 111322 AF1104-like
1 1 SCOP 111332 NAD kinase-like
1 1 SCOP 111343 CbiD-like
1 1 SCOP 117458 FumA C-terminal domain-like
1 1 SCOP 117786 Ribosomal protein S24e
1 1 SCOP 117795 Formaldehyde-activating enzyme, FAE
1 1 SCOP 117857 Alpha-acetolactate decarboxylase-like
1 1 SCOP 118216 Proton glutamate symport protein
1 1 SCOP 140377 ChaB-like
1 1 SCOP 140479 LemA-like
1 1 SCOP 141368 UbiD middle domain-like
1 1 SCOP 141735 HisI-like
1 1 SCOP 141755 PdxS-like
1 1 SCOP 141942 Thi4-like
1 1 SCOP 141979 AF0055-like
1 1 SCOP 142339 CofD-like
1 1 SCOP 142536 AF0625-like
1 1 SCOP 142622 Met-10+ protein-like
1 1 SCOP 142701 RibD C-terminal domain-like
1 1 SCOP 142755 NadA-like
1 1 SCOP 142789 TM0189-like
1 1 SCOP 143448 AMMECR1-like
1 1 SCOP 143866 CorA soluble domain-like
1 1 SCOP 143916 RNase Z-like
1 1 SCOP 143976 lvD/EDD N-terminal domain-like
1 1 SCOP 144031 Nq06-like
1 1 SCOP 144084 Magnesium transport protein CorA, transmembrane region
1 1 SCOP 158338 Rps19E-like
1 1 SCOP 158706 Achaeal helicase C-terminal domain
1 1 SCOP 159164 MTH863-like
1 1 SCOP 159444 SP0239-like
1 1 SCOP 159464 AF0587 domain-like
1 1 SCOP 159518 AF1056-like
1 1 SCOP 159523 AF0751-like
1 1 SCOP 159526 PurP N-terminal domain-like
1 1 SCOP 159697 TRM1-like
1 1 SCOP 159704 SepSecS-like
1 1 SCOP 159720 mannose-1-phosphate guanylyl transferase
1 1 SCOP 159723 MM2497-like
1 1 SCOP 159768 Phosphomethylpyrimidine kinase C-terminal domain-like
1 1 SCOP 159942 MM3350-like
1 1 SCOP 160289 YbaA-like
1 1 SCOP 160566 DVU1097-like
1 1 SCOP 160611 PH0223-like
1 1 SCOP 160861 Alkylsulfatase-like
1 1 SCOP 160883 CheD-like
1 1 SCOP 160976 AF1531-like
1 1 SCOP 161094 MgtE membrane domain-like

The following families have one or more weak hits: