Family Assignments

Domains Proteins SCOP Link Families
214 211 SCOP 88854 Protein kinases, catalytic subunit
71 71 SCOP 52592 G proteins
68 68 SCOP 52641 Motor proteins
37 30 SCOP 81269 Extended AAA-ATPase domain
31 23 SCOP 81268 Tandem AAA-ATPase domain
28 21 SCOP 52686 ABC transporter ATPase domain-like
26 26 SCOP 52805 Higher-molecular-weight phosphotyrosine protein phosphatases
24 24 SCOP 51751 Tyrosine-dependent oxidoreductases
21 12 SCOP 53068 Actin/HSP70
20 20 SCOP 54496 UBC-related
18 18 SCOP 50979 WD40-repeat
18 18 SCOP 52375 Class I aminoacyl-tRNA synthetases (RS), catalytic domain
16 16 SCOP 53653 Arylsulfatase
15 15 SCOP 47114 Nucleosome core histones
15 15 SCOP 51446 Amylase, catalytic domain
15 15 SCOP 56205 Hect, E3 ligase catalytic domain
14 14 SCOP 55682 Class II aminoacyl-tRNA synthetase (aaRS)-like, catalytic domain
14 14 SCOP 56251 Proteasome subunits
14 14 SCOP 56310 Protein serine/threonine phosphatase
13 13 SCOP 50892 Cyclophilin (peptidylprolyl isomerase)
12 12 SCOP 82568 Ubiquitin carboxyl-terminal hydrolase, UCH
12 12 SCOP 117702 Polypeptide N-acetylgalactosaminyltransferase 1, N-terminal domain
10 10 SCOP 53417 GABA-aminotransferase-like
10 10 SCOP 53687 Tryptophan synthase beta subunit-like PLP-dependent enzymes
10 10 SCOP 53721 ALDH-like
10 9 SCOP 54002 Papain-like
9 9 SCOP 47502 Calmodulin-like
9 7 SCOP 56067 BC ATP-binding domain-like
9 9 SCOP 56802 Acetyl-CoA synthetase-like
8 8 SCOP 48372 Armadillo repeat
8 6 SCOP 52441 BC N-terminal domain-like
8 8 SCOP 52800 Dual specificity phosphatase-like
8 8 SCOP 53384 AAT-like
7 6 SCOP 47875 Annexin
7 7 SCOP 48066 DBL homology domain (DH-domain)
7 7 SCOP 51396 FMN-linked oxidoreductases
7 7 SCOP 51431 Aldo-keto reductases (NADP)
7 7 SCOP 52318 Class I glutamine amidotransferases (GAT)
7 7 SCOP 52541 Nucleotide and nucleoside kinases
7 7 SCOP 52652 Nitrogenase iron protein-like
7 7 SCOP 52901 Glutathione peroxidase-like
7 3 SCOP 55754 Gelsolin-like
7 7 SCOP 56646 Medium chain acyl-CoA dehydrogenase, NM (N-terminal and middle) domains
7 7 SCOP 74771 Clathrin adaptor core protein
7 7 SCOP 81605 PP2C-like
6 6 SCOP 47204 Medium chain acyl-CoA dehydrogenase-like, C-terminal domain
6 6 SCOP 47577 Calponin-homology domain, CH-domain
6 6 SCOP 48404 Ankyrin repeat
6 6 SCOP 48548 PDEase
6 6 SCOP 52491 Tubulin, GTPase domain
6 6 SCOP 53402 Cystathionine synthase-like
6 6 SCOP 53499 Serine carboxypeptidase-like
6 4 SCOP 53902 Thiolase-related
6 6 SCOP 55921 Creatinase/aminopeptidase
6 5 SCOP 55935 Guanido kinase catalytic domain
6 5 SCOP 63412 MPP-like
6 3 SCOP 89572 Biotin dependent carboxylase carboxyltransferase domain
6 6 SCOP 101448 Formin homology 2 domain (FH2 domain)
5 5 SCOP 48226 Class I alpha-1;2-mannosidase, catalytic domain
5 5 SCOP 48265 Cytochrome P450
5 5 SCOP 48426 Sec7 domain
5 5 SCOP 51736 Alcohol dehydrogenase-like, C-terminal domain
5 5 SCOP 51800 Glyceraldehyde-3-phosphate dehydrogenase-like, N-terminal domain
5 5 SCOP 51868 6-phosphogluconate dehydrogenase-like, N-terminal domain
5 5 SCOP 52103 Crotonase-like
5 5 SCOP 53272 Phosphoribosyltransferases (PRTases)
5 5 SCOP 53660 Dimeric isocitrate & isopropylmalate dehydrogenases
5 5 SCOP 54929 Canonical RBD
5 5 SCOP 55730 N-acetyl transferase, NAT
5 5 SCOP 56171 Phoshoinositide 3-kinase (PI3K), catalytic domain
5 5 SCOP 75521 Clathrin coat assembly domain
5 5 SCOP 81838 BEACH domain
4 4 SCOP 48246 Protein prenyltransferases
4 4 SCOP 48360 p120GAP domain-like
4 4 SCOP 48367 Ras GEF
4 4 SCOP 49448 Second domain of Mu2 adaptin subunit (ap50) of ap2 adaptor
4 4 SCOP 50136 Alcohol dehydrogenase-like, N-terminal domain
4 4 SCOP 50282 Cold shock DNA-binding domain-like
4 4 SCOP 50678 ValRS/IleRS/LeuRS editing domain
4 4 SCOP 51550 beta-N-acetylhexosaminidase catalytic domain
4 4 SCOP 51696 Mammalian PLC
4 4 SCOP 51830 Formate/glycerate dehydrogenases, NAD-domain
4 4 SCOP 51848 LDH N-terminal domain-like
4 4 SCOP 51943 FAD/NAD-linked reductases, N-terminal and central domains
4 4 SCOP 52778 CAT-like
4 4 SCOP 53118 DnaQ-like 3'-5' exonuclease
4 4 SCOP 53204 Bacterial dinuclear zinc exopeptidases
4 4 SCOP 54212 Translational machinery components
4 3 SCOP 54237 Ubiquitin-related
4 4 SCOP 54535 FKBP immunophilin/proline isomerase
4 3 SCOP 54632 CBS-domain pair
4 4 SCOP 55308 Tubulin, C-terminal domain
4 4 SCOP 55425 FAD/NAD-linked reductases, dimerisation (C-terminal) domain
4 4 SCOP 55762 Cofilin-like
4 4 SCOP 56328 Lactate & malate dehydrogenases, C-terminal domain
4 4 SCOP 56673 DNA polymerase I
4 4 SCOP 64422 Inositol polyphosphate 5-phosphatase (IPP5)
4 4 SCOP 75633 Cullin homology domain
4 2 SCOP 82424 Choline/Carnitine O-acyltransferase
4 4 SCOP 100921 Heat shock protein 70kD (HSP70), peptide-binding domain
4 4 SCOP 102422 Myotubularin-like phosphatases
3 3 SCOP 47588 Domain of poly(ADP-ribose) polymerase
3 3 SCOP 48351 BCR-homology GTPase activation domain (BH-domain)
3 3 SCOP 48385 HEAT repeat
3 3 SCOP 48558 L-aspartase/fumarase
3 3 SCOP 48577 Isoprenyl diphosphate synthases
3 3 SCOP 50448 Elongation factors
3 3 SCOP 50776 Third domain of FERM
3 3 SCOP 50940 Sialidases (neuraminidases)
3 3 SCOP 51487 beta-glycanases
3 3 SCOP 51553 NagZ-like
3 3 SCOP 51883 Aminoacid dehydrogenase-like, C-terminal domain
3 3 SCOP 52211 Succinyl-CoA synthetase domains
3 3 SCOP 52403 N-type ATP pyrophosphatases
3 2 SCOP 52513 NagB-like
3 3 SCOP 52670 RecA protein-like (ATPase-domain)
3 3 SCOP 52744 Subtilases
3 3 SCOP 53467 1,3-glucuronyltransferase
3 3 SCOP 53733 Aconitase iron-sulfur domain
3 3 SCOP 53791 Tetrapyrrole methylase
3 3 SCOP 54229 Ribonuclease PH domain 1-like
3 3 SCOP 54920 Nucleoside diphosphate kinase, NDK
3 2 SCOP 55327 PurM N-terminal domain-like
3 3 SCOP 55363 Homoserine dehydrogenase-like
3 3 SCOP 55812 MutT-like
3 3 SCOP 55875 Heat shock protein 90, HSP90, N-terminal domain
3 3 SCOP 55879 DNA gyrase/MutL, N-terminal domain
3 1 SCOP 55974 S-adenosylmethionine synthetase
3 2 SCOP 56043 PurM C-terminal domain-like
3 3 SCOP 56108 Phosphatidylinositol phosphate kinase IIbeta, PIPK IIbeta
3 3 SCOP 56236 Class II glutamine amidotransferases
3 3 SCOP 56288 Glyoxalase II (hydroxyacylglutathione hydrolase)
3 3 SCOP 56301 Purple acid phosphatase-like
3 3 SCOP 56530 FAH
3 3 SCOP 56656 Inositol monophosphatase/fructose-1,6-bisphosphatase-like
3 3 SCOP 56816 Sec1/munc18-like (SM) proteins
3 3 SCOP 63984 Sir2 family of transcriptional regulators
3 3 SCOP 64269 PX domain
3 3 SCOP 64485 RNA-polymerase beta
3 3 SCOP 64490 RNA-polymerase beta-prime
3 2 SCOP 69646 Arp2/3 complex subunits
3 3 SCOP 81656 Meta-cation ATPase, catalytic domain P
3 3 SCOP 82458 Trunk domain of Sec23/24
3 2 SCOP 82636 MaoC-like
3 3 SCOP 89125 Nop domain
3 3 SCOP 100888 Lesion bypass DNA polymerase (Y-family), catalytic domain
3 3 SCOP 102755 Hsp90 middle domain
3 3 SCOP 103507 Mitochondrial carrier
3 3 SCOP 111188 Inositol polyphosphate kinase (IPK)
3 3 SCOP 111353 Ammonium transporter
3 3 SCOP 140991 FtsH protease domain-like
3 3 SCOP 143927 beta-CASP RNA-metabolising hydrolases
2 2 SCOP 46566 Chaperone J-domain
2 2 SCOP 46627 monodomain cytochrome c
2 1 SCOP 46967 Spectrin repeat
2 2 SCOP 47032 Second domain of FERM
2 2 SCOP 47617 Glutathione S-transferase (GST), C-terminal domain
2 2 SCOP 47896 Transducin (alpha subunit), insertion domain
2 2 SCOP 47918 C-terminal domain of alpha and beta subunits of F1 ATP synthase
2 1 SCOP 47924 Ypt/Rab-GAP domain of gyp1p
2 2 SCOP 47955 Cyclin
2 2 SCOP 47974 Ribosomal protein S7
2 2 SCOP 48114 CCP-like
2 2 SCOP 48174 Cryptochrome/photolyase FAD-binding domain
2 1 SCOP 48243 Terpene synthases
2 2 SCOP 48440 Protein prenylyltransferase
2 2 SCOP 48453 Tetratricopeptide repeat (TPR)
2 1 SCOP 50263 Single strand DNA-binding domain, SSB
2 2 SCOP 50277 Myf domain
2 2 SCOP 50307 DNA ligase/mRNA capping enzyme postcatalytic domain
2 2 SCOP 50461 Ribosomal protein L3
2 2 SCOP 50476 PNP-oxidase like
2 2 SCOP 50616 N-terminal domain of alpha and beta subunits of F1 ATP synthase
2 1 SCOP 51210 cAMP-binding domain
2 2 SCOP 51231 Biotinyl/lipoyl-carrier proteins and domains
2 2 SCOP 51247 BC C-terminal domain-like
2 2 SCOP 51381 Tryptophan biosynthesis enzymes
2 2 SCOP 51413 Inosine monophosphate dehydrogenase (IMPDH)
2 2 SCOP 51420 Alanine racemase-like, N-terminal domain
2 2 SCOP 51570 Class I aldolase
2 2 SCOP 52017 LeuD-like
2 2 SCOP 52167 Ribosomal protein L4
2 2 SCOP 52243 Cobalamin (vitamin B12)-binding domain
2 2 SCOP 52314 Ribosomal protein S2
2 2 SCOP 52325 DJ-1/PfpI
2 2 SCOP 52432 ETFP subunits
2 2 SCOP 52773 Histone deacetylase, HDAC
2 2 SCOP 52926 Branched-chain alpha-keto acid dehydrogenase beta-subunit, C-terminal-domain
2 1 SCOP 53089 Glycerol kinase
2 2 SCOP 53168 Purine and uridine phosphorylases
2 1 SCOP 53188 Pancreatic carboxypeptidases
2 2 SCOP 53201 Leucine aminopeptidase, C-terminal domain
2 2 SCOP 53296 Phosphoribosylpyrophosphate synthetase-like
2 2 SCOP 53351 Arginine methyltransferase
2 2 SCOP 53461 UDP-glucose pyrophosphorylase
2 2 SCOP 53542 Thioesterases
2 2 SCOP 53614 Ribokinase-like
2 2 SCOP 53672 Aspartate/ornithine carbamoyltransferase
2 1 SCOP 53739 Phosphoglucomutase, first 3 domains
2 2 SCOP 53766 Oligosaccharide phosphorylase
2 1 SCOP 53785 Phosphofructokinase
2 2 SCOP 53851 Phosphate binding protein-like
2 1 SCOP 54207 Hexose-1-phosphate uridylyltransferase
2 2 SCOP 54224 DNA gyrase/MutL, second domain
2 2 SCOP 54792 Eukaryotic type KH-domain (KH-domain type I)
2 1 SCOP 54981 EF-G/eEF-2 domains III and V
2 2 SCOP 55074 Adenylyl and guanylyl cyclase catalytic domain
2 2 SCOP 55316 L30e/L7ae ribosomal proteins
2 2 SCOP 55323 ERF1/Dom34 C-terminal domain-like
2 2 SCOP 55348 GAPDH-like
2 2 SCOP 55419 Translation initiation factor eIF4e
2 2 SCOP 55505 Neurolysin-like
2 1 SCOP 55748 N-myristoyl transferase, NMT
2 1 SCOP 55946 TATA-box binding protein (TBP), C-terminal domain
2 2 SCOP 55958 Phosphoglucomutase, C-terminal domain
2 1 SCOP 55983 DNA polymerase processivity factor
2 1 SCOP 56015 Nitrite and sulphite reductase 4Fe-4S domain-like
2 2 SCOP 56081 Succinyl-CoA synthetase, beta-chain, N-terminal domain
2 2 SCOP 56220 DNase I-like
2 2 SCOP 56318 Nitrilase
2 2 SCOP 56416 Poly(ADP-ribose) polymerase, C-terminal domain
2 2 SCOP 56753 D-aminoacid aminotransferase-like PLP-dependent enzymes
2 2 SCOP 56797 Dehydroquinate synthase, DHQS
2 2 SCOP 56895 Aquaporin-like
2 2 SCOP 57851 RING finger domain, C3HC4
2 2 SCOP 63888 P-domain of calnexin/calreticulin
2 2 SCOP 64357 Synatpobrevin N-terminal domain
2 2 SCOP 69001 FAD-dependent thiol oxidase
2 2 SCOP 69236 Calnexin/calreticulin
2 2 SCOP 69746 Pseudouridine synthase II TruB
2 2 SCOP 74789 Cullin repeat
2 2 SCOP 74904 Lectin leg-like
2 2 SCOP 75305 Amidase signature (AS) enzymes
2 2 SCOP 81288 RhoGDI-like
2 2 SCOP 81300 DNA polymerase beta-like
2 2 SCOP 81659 Metal cation-transporting ATPase, ATP-binding domain N
2 2 SCOP 82110 MIR domain
2 2 SCOP 82267 TatD Mg-dependent DNase-like
2 2 SCOP 82583 G domain-linked domain
2 2 SCOP 88683 Eukaryotic ODC-like
2 2 SCOP 88714 alpha-mannosidase
2 2 SCOP 88741 Branched-chain alpha-keto acid dehydrogenase Pyr module
2 2 SCOP 88766 Branched-chain alpha-keto acid dehydrogenase PP module
2 2 SCOP 89763 Ubiquitin activating enzymes (UBA)
2 2 SCOP 90084 Glutaminase
2 2 SCOP 100935 Heat shock protein 70kD (HSP70), C-terminal subdomain
2 2 SCOP 100948 Isochorismatase-like hydrolases
2 2 SCOP 100998 SLIDE domain
2 2 SCOP 101153 Mob1/phocein
2 2 SCOP 101984 Pirin-like
2 2 SCOP 110020 ERO1-like
2 2 SCOP 110509 NLI interacting factor-like phosphatase
2 1 SCOP 117002 Exportin HEAT-like repeat
2 2 SCOP 117714 Hypothetical esterase YJL068C
2 2 SCOP 117893 Band 7/SPFH domain
2 2 SCOP 140819 B56-like
2 1 SCOP 142678 Glycine dehydrogenase subunits (GDC-P)
2 2 SCOP 143906 Gamma-glutamyltranspeptidase-like
2 2 SCOP 143959 Sulfatase-modifying factor-like
2 2 SCOP 159112 RNB domain-like
2 2 SCOP 159623 Fumble-like
2 2 SCOP 159747 PHB depolymerase-like
2 2 SCOP 159756 O-acetyltransferase
2 2 SCOP 159858 Autophagin-like
2 1 SCOP 160105 Acetoacetate decarboxylase-like
1 1 SCOP 46463 Globins
1 1 SCOP 46549 Fumarate reductase/Succinate dehydogenase iron-sulfur protein, C-terminal domain
1 1 SCOP 46610 Fe,Mn superoxide dismutase (SOD), N-terminal domain
1 1 SCOP 46676 Cytochrome bc1 domain
1 1 SCOP 47221 alpha-catenin/vinculin
1 1 SCOP 47253 Ribonucleotide reductase-like
1 1 SCOP 47324 Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases
1 1 SCOP 47371 Bromodomain
1 1 SCOP 47447 Signal peptide-binding domain
1 1 SCOP 47460 HLH, helix-loop-helix DNA-binding domain
1 1 SCOP 47645 Methionine synthase domain
1 1 SCOP 47662 t-snare proteins
1 1 SCOP 47669 N-terminal domain of cbl (N-cbl)
1 1 SCOP 47695 Cytochrome c oxidase subunit h
1 1 SCOP 47808 5' to 3' exonuclease, C-terminal subdomain
1 1 SCOP 48109 Carbamoyl phosphate synthetase, large subunit connection domain
1 1 SCOP 48154 Mismatch glycosylase
1 1 SCOP 48157 DNA repair glycosylase, 2 C-terminal domains
1 1 SCOP 48180 Hydroxyisobutyrate and 6-phosphogluconate dehydrogenase domain
1 1 SCOP 48187 HCDH C-domain-like
1 1 SCOP 48209 Glucoamylase
1 1 SCOP 48390 Clathrin heavy chain proximal leg segment
1 1 SCOP 48393 Clathrin heavy-chain linker domain
1 1 SCOP 48399 Phoshoinositide 3-kinase (PI3K) helical domain
1 1 SCOP 48446 14-3-3 protein
1 1 SCOP 48465 ENTH domain
1 1 SCOP 48468 VHS domain
1 1 SCOP 48480 Cytochrome c oxidase subunit E
1 1 SCOP 48543 P1 nuclease
1 1 SCOP 48580 Squalene synthase
1 1 SCOP 48593 GroEL chaperone, ATPase domain
1 1 SCOP 48604 Allosteric chorismate mutase
1 1 SCOP 49349 Alpha-adaptin ear subdomain-like
1 1 SCOP 49550 Multidomain cupredoxins
1 1 SCOP 49803 beta-Galactosidase/glucuronidase, N-terminal domain
1 1 SCOP 50006 Hyaluronate lyase-like, central domain
1 1 SCOP 50023 Rieske iron-sulfur protein (ISP)
1 1 SCOP 50114 C-terminal domain of ribosomal protein L2
1 1 SCOP 50183 Sm motif of small nuclear ribonucleoproteins, SNRNP
1 1 SCOP 50194 Ribosomal protein L14
1 1 SCOP 50325 Inorganic pyrophosphatase
1 1 SCOP 50438 NADPH-cytochrome p450 reductase FAD-binding domain-like
1 1 SCOP 50466 EF-Tu/eEF-1alpha/eIF2-gamma C-terminal domain
1 1 SCOP 50646 Pepsin-like
1 1 SCOP 50708 Cdc48 N-terminal domain-like
1 1 SCOP 50755 Phosphotyrosine-binding domain (PTB)
1 1 SCOP 50801 Pyruvate kinase beta-barrel domain
1 1 SCOP 50986 Regulator of chromosome condensation RCC1
1 1 SCOP 50990 Clathrin heavy-chain terminal domain
1 1 SCOP 50994 Prolyl oligopeptidase, N-terminal domain
1 1 SCOP 51191 Type I phosphomannose isomerase
1 1 SCOP 51194 Homogentisate dioxygenase
1 1 SCOP 51284 dUTPase-like
1 1 SCOP 51352 Triosephosphate isomerase (TIM)
1 1 SCOP 51367 Histidine biosynthesis enzymes
1 1 SCOP 51375 Decarboxylase
1 1 SCOP 51427 "Hypothetical" protein ybl036c
1 1 SCOP 51534 Type II chitinase
1 1 SCOP 51557 Adenosine/AMP deaminase
1 1 SCOP 51591 Class II FBP aldolase
1 1 SCOP 51594 5-aminolaevulinate dehydratase, ALAD (porphobilinogen synthase)
1 1 SCOP 51605 Enolase
1 1 SCOP 51622 Pyruvate kinase
1 1 SCOP 51691 NadC C-terminal domain-like
1 1 SCOP 51704 Methylmalonyl-CoA mutase, N-terminal (CoA-binding) domain
1 1 SCOP 51714 tRNA-guanine transglycosylase
1 1 SCOP 51727 Uroporphyrinogen decarboxylase, UROD
1 1 SCOP 51731 Methylenetetrahydrofolate reductase
1 1 SCOP 51900 CoA-binding domain
1 1 SCOP 51913 FAD-linked reductases, N-terminal domain
1 1 SCOP 51931 GDI-like N domain
1 1 SCOP 51934 Succinate dehydrogenase/fumarate reductase flavoprotein N-terminal domain
1 1 SCOP 51972 N-terminal domain of adrenodoxin reductase-like
1 1 SCOP 52002 R1 subunit of ribonucleotide reductase, C-terminal domain
1 1 SCOP 52022 Carbamoyl phosphate synthetase, small subunit N-terminal domain
1 1 SCOP 52030 GroEL-like chaperone, apical domain
1 1 SCOP 52034 Group II chaperonin (CCT, TRIC), apical domain
1 1 SCOP 52052 Rna1p (RanGAP1), N-terminal domain
1 1 SCOP 52068 U2A'-like
1 1 SCOP 52088 CRAL/TRIO domain
1 1 SCOP 52097 Clp protease, ClpP subunit
1 1 SCOP 52142 Uracil-DNA glycosylase
1 1 SCOP 52152 FabD-like
1 1 SCOP 52162 Ribosomal protein L13
1 1 SCOP 52231 Cytochrome p450 reductase N-terminal domain-like
1 1 SCOP 52256 N5-CAIR mutase (phosphoribosylaminoimidazole carboxylase, PurE)
1 1 SCOP 52300 S-adenosylhomocystein hydrolase
1 1 SCOP 52331 Aspartyl dipeptidase PepE
1 1 SCOP 52344 Reductases
1 1 SCOP 52397 Adenylyltransferase
1 1 SCOP 52419 Nucleoside phosphorylase/phosphoribosyltransferase catalytic domain
1 1 SCOP 52426 Cryptochrome/photolyase, N-terminal domain
1 1 SCOP 52468 Deoxyhypusine synthase, DHS
1 1 SCOP 52471 C-terminal domain of the electron transfer flavoprotein alpha subunit
1 1 SCOP 52484 Transhydrogenase domain III (dIII)
1 1 SCOP 52508 Homo-oligomeric flavin-containing Cys decarboxylases, HFCD
1 1 SCOP 52572 Adenosine-5'phosphosulfate kinase (APS kinase)
1 1 SCOP 52584 Phosphoribulokinase/pantothenate kinase
1 1 SCOP 52589 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase, kinase domain
1 1 SCOP 52769 Arginase-like amidino hydrolases
1 1 SCOP 52834 Thioltransferase
1 1 SCOP 52936 Pyruvate kinase, C-terminal domain
1 1 SCOP 52944 ATP synthase (F1-ATPase), gamma subunit
1 1 SCOP 52973 ITPase (Ham1)
1 1 SCOP 53045 5' to 3' exonuclease catalytic domain
1 1 SCOP 53143 ERF1/Dom34 middle domain-like
1 1 SCOP 53214 LigB-like
1 1 SCOP 53224 Aminoacid dehydrogenases
1 1 SCOP 53240 Malic enzyme N-domain
1 1 SCOP 53255 Cofactor-dependent phosphoglycerate mutase
1 1 SCOP 53258 Histidine acid phosphatase
1 1 SCOP 53267 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase, phosphatase domain
1 1 SCOP 53329 Formyltransferase
1 1 SCOP 53342 Fibrillarin homologue
1 1 SCOP 53496 Prolyl oligopeptidase, C-terminal domain
1 1 SCOP 53506 Gastric lipase
1 1 SCOP 53509 Proline iminopeptidase-like
1 1 SCOP 53525 Epoxide hydrolase
1 1 SCOP 53558 Fungal lipases
1 1 SCOP 53598 Dihydrofolate reductases
1 1 SCOP 53698 double-SIS domain
1 1 SCOP 53701 Phosphoglucose isomerase, PGI
1 1 SCOP 53749 Phosphoglycerate kinase
1 1 SCOP 53775 Glutaminase/Asparaginase
1 1 SCOP 53796 PEP carboxykinase C-terminal domain
1 1 SCOP 53921 Fe-only hydrogenase
1 1 SCOP 54044 Transglutaminase core
1 1 SCOP 54050 Ubiquitin carboxyl-terminal hydrolase UCH-L
1 1 SCOP 54054 Adenain-like
1 1 SCOP 54193 L15e
1 1 SCOP 54198 HIT (HINT, histidine triad) family of protein kinase-interacting proteins
1 1 SCOP 54232 GHMP Kinase, N-terminal domain
1 1 SCOP 54256 First domain of FERM
1 1 SCOP 54507 Diaminopimelate epimerase
1 1 SCOP 54519 Transcriptional factor tubby, C-terminal domain
1 1 SCOP 54586 Cdc48 domain 2-like
1 1 SCOP 54594 Glyoxalase I (lactoylglutathione lyase)
1 1 SCOP 54602 Extradiol dioxygenases
1 1 SCOP 54649 DLC
1 1 SCOP 54687 Ribosomal protein L10e
1 1 SCOP 54696 BTB/POZ domain
1 1 SCOP 54720 Fe,Mn superoxide dismutase (SOD), C-terminal domain
1 1 SCOP 54748 Ribosomal L11/L12e N-terminal domain
1 1 SCOP 54815 Prokaryotic type KH domain (KH-domain type II)
1 1 SCOP 54827 Enolase N-terminal domain-like
1 1 SCOP 55036 NAD-binding domain of HMG-CoA reductase
1 1 SCOP 55069 Peptide methionine sulfoxide reductase
1 1 SCOP 55160 eIF1-like
1 1 SCOP 55209 Enolpyruvate transferase, EPT
1 1 SCOP 55249 PCD-like
1 1 SCOP 55283 Ribosomal protein L5
1 1 SCOP 55288 RPB5
1 1 SCOP 55299 YjgF/L-PSP
1 1 SCOP 55368 Dihydrodipicolinate reductase-like
1 1 SCOP 55376 Glucose 6-phosphate dehydrogenase-like
1 1 SCOP 55395 Bactericidal permeability-increasing protein, BPI
1 1 SCOP 55482 N-terminal domain of eukaryotic peptide chain release factor subunit 1, ERF1
1 1 SCOP 55525 TNF-alpha converting enzyme, TACE, catalytic domain
1 1 SCOP 55551 SH2 domain
1 1 SCOP 55625 6-pyruvoyl tetrahydropterin synthase
1 1 SCOP 55638 Cell cycle regulatory proteins
1 1 SCOP 55712 Clathrin adaptor appendage, alpha and beta chain-specific domain
1 1 SCOP 55771 Profilin (actin-binding protein)
1 1 SCOP 55782 GAF domain
1 1 SCOP 55817 5'-nucleotidase (syn. UDP-sugar hydrolase), C-terminal domain
1 1 SCOP 55832 Thymidylate synthase/dCMP hydroxymethylase
1 1 SCOP 55910 Ribosome anti-association factor eIF6 (aIF6)
1 1 SCOP 56004 Molybdenum cofactor-binding domain
1 1 SCOP 56020 The spindle assembly checkpoint protein mad2
1 1 SCOP 56048 Ribosomal protein S8
1 1 SCOP 56088 Eukaryotic glutathione synthetase ATP-binding domain
1 1 SCOP 56092 ATP-dependent DNA ligase catalytic domain
1 1 SCOP 56105 SAICAR synthase
1 1 SCOP 56210 Nitrile hydratase alpha chain
1 1 SCOP 56277 S-adenosylmethionine decarboxylase
1 1 SCOP 56323 ADC synthase
1 1 SCOP 56361 Eukaryotic DNA topoisomerase I, catalytic core
1 1 SCOP 56426 Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain
1 1 SCOP 56508 Methionine synthase SAM-binding domain
1 1 SCOP 56535 Aromatic aminoacid monoxygenases, catalytic and oligomerization domains
1 1 SCOP 56543 Substrate-binding domain of HMG-CoA reductase
1 1 SCOP 56554 Insert subdomain of RNA polymerase alpha subunit
1 1 SCOP 56602 beta-Lactamase/D-ala carboxypeptidase
1 1 SCOP 56635 Heme-dependent catalases
1 1 SCOP 56691 T7 RNA polymerase
1 1 SCOP 56713 Prokaryotic type I DNA topoisomerase
1 1 SCOP 56720 Type II DNA topoisomerase
1 1 SCOP 56727 DNA topoisomerase IV, alpha subunit
1 1 SCOP 56742 Eukaryotic DNA topoisomerase I, N-terminal DNA-binding fragment
1 1 SCOP 56809 Ribosomal protein L1
1 1 SCOP 57799 Casein kinase II beta subunit
1 1 SCOP 57911 PHD domain
1 1 SCOP 57998 Tropomyosin
1 1 SCOP 63381 Ferredoxin reductase FAD-binding domain-like
1 1 SCOP 63434 Fumarylacetoacetate hydrolase, FAH, N-terminal domain
1 1 SCOP 63550 Penta-EF-hand proteins
1 1 SCOP 63611 Pumilio repeat
1 1 SCOP 63708 Ganglioside M2 (gm2) activator
1 1 SCOP 63801 ATP sulfurylase N-terminal domain
1 1 SCOP 63883 MoeA N-terminal region -like
1 1 SCOP 63917 Dihydroorotase
1 1 SCOP 63971 Inosicase
1 1 SCOP 63976 Pantothenate synthetase (Pantoate-beta-alanine ligase, PanC)
1 1 SCOP 63979 ATP sulfurylase catalytic domain
1 1 SCOP 64006 Undecaprenyl diphosphate synthase
1 1 SCOP 64089 BadF/BadG/BcrA/BcrD-like
1 1 SCOP 64136 N-acetylglucosaminyltransferase I
1 1 SCOP 64198 AICAR transformylase domain of bifunctional purine biosynthesis enzyme ATIC
1 1 SCOP 64264 Prokaryotic ribosomal protein L17
1 1 SCOP 64338 Leukotriene A4 hydrolase catalytic domain
1 1 SCOP 64372 3,4-dihydroxy-2-butanone 4-phosphate synthase, DHBP synthase, RibB
1 1 SCOP 64511 Phosphoserine phosphatase
1 1 SCOP 68924 PEP carboxykinase N-terminal domain
1 1 SCOP 69013 alpha-ketoacid dehydrogenase kinase, N-terminal domain
1 1 SCOP 69061 Arp2/3 complex 21 kDa subunit ARPC3
1 1 SCOP 69210 APC10-like
1 1 SCOP 69222 PepX C-terminal domain-like
1 1 SCOP 69337 Alpha subunit of glutamate synthase, C-terminal domain
1 1 SCOP 69341 C-terminal domain of adenylylcyclase associated protein
1 1 SCOP 69557 Spermidine synthase
1 1 SCOP 69573 Molybdenum cofactor biosynthesis protein MoeB
1 1 SCOP 69602 L-histidinol dehydrogenase HisD
1 1 SCOP 69804 alpha-ketoacid dehydrogenase kinase, C-terminal domain
1 1 SCOP 69865 Argininosuccinate synthetase, C-terminal domain
1 1 SCOP 69912 Clc chloride channel
1 1 SCOP 74656 CoA transferase alpha subunit-like
1 1 SCOP 74657 CoA transferase beta subunit-like
1 1 SCOP 74714 acyl-CoA oxidase C-terminal domains
1 1 SCOP 74785 Translin
1 1 SCOP 74857 gamma-adaptin C-terminal appendage domain-like
1 1 SCOP 74911 Aldose 1-epimerase (mutarotase)
1 1 SCOP 75041 SelR domain
1 1 SCOP 75093 Hypothetical protein YgbM (EC1530)
1 1 SCOP 75131 B12-dependent (class II) ribonucleotide reductase
1 1 SCOP 75195 Gluconate kinase
1 1 SCOP 75273 Glycogenin
1 1 SCOP 75285 Ccg1/TafII250-interacting factor B (Cib)
1 1 SCOP 75292 YjeF C-terminal domain-like
1 1 SCOP 75434 Divalent ion tolerance proteins CutA (CutA1)
1 1 SCOP 75600 acyl-CoA oxidase N-terminal domains
1 1 SCOP 75621 Release factor
1 1 SCOP 81291 Arrestin/Vps26-like
1 1 SCOP 81314 p53 DNA-binding domain-like
1 1 SCOP 81380 Skp1 dimerisation domain-like
1 1 SCOP 81530 Non-heme 11 kDa protein of cytochrome bc1 complex (Ubiquinol-cytochrome c reductase)
1 1 SCOP 81589 Poly(A) polymerase, PAP, N-terminal domain
1 1 SCOP 81630 Poly(A) polymerase, PAP, middle domain
1 1 SCOP 81652 Calcium ATPase, transduction domain A
1 1 SCOP 81664 Calcium ATPase, transmembrane domain M
1 1 SCOP 81812 Helical domain of Sec23/24
1 1 SCOP 81843 Mannitol 2-dehydrogenase
1 1 SCOP 81895 IP3 receptor type 1 binding core, domain 2
1 1 SCOP 82115 ATP-dependent riboflavin kinase-like
1 1 SCOP 82191 Acireductone dioxygenase
1 1 SCOP 82194 Hypoxia-inducible factor HIF ihhibitor (FIH1)
1 1 SCOP 82200 Histone lysine methyltransferases
1 1 SCOP 82253 alpha-D-glucuronidase/Hyaluronidase catalytic domain
1 1 SCOP 82283 Homocysteine S-methyltransferase
1 1 SCOP 82385 phosphatase domain of polynucleotide kinase
1 1 SCOP 82388 Predicted hydrolases Cof
1 1 SCOP 82515 PfkB-like kinase
1 1 SCOP 82545 GckA/TtuD-like
1 1 SCOP 82645 The homologous-pairing domain of Rad52 recombinase
1 1 SCOP 82661 Poly A polymerase head domain-like
1 1 SCOP 82755 C-terminal, gelsolin-like domain of Sec23/24
1 1 SCOP 88656 alpha-mannosidase, C-terminal domain
1 1 SCOP 88698 PUA domain
1 1 SCOP 88704 Phosphoenolpyruvate mutase/Isocitrate lyase-like
1 1 SCOP 88735 TK-like Pyr module
1 1 SCOP 88760 TK-like PP module
1 1 SCOP 88771 PFOR PP module
1 1 SCOP 88784 rRNA adenine dimethylase-like
1 1 SCOP 88786 C5 cytosine-specific DNA methylase, DCM
1 1 SCOP 89032 Cobalamin adenosyltransferase
1 1 SCOP 89416 gamma-Butyrobetaine hydroxylase
1 1 SCOP 89489 Isoaspartyl dipeptidase, catalytic domain
1 1 SCOP 89494 HMGL-like
1 1 SCOP 89503 Ketopantoate hydroxymethyltransferase PanB
1 1 SCOP 89716 XPF/Rad1/Mus81 nuclease
1 1 SCOP 89746 Catalytic, N-terminal domain of histone methyltransferase Dot1l
1 1 SCOP 89797 CoA-transferase family III (CaiB/BaiF)
1 1 SCOP 89800 Deoxycytidylate deaminase-like
1 1 SCOP 89818 Mago nashi protein
1 1 SCOP 90097 Capz alpha-1 subunit
1 1 SCOP 90100 Capz beta-1 subunit
1 1 SCOP 100908 MIF4G domain-like
1 1 SCOP 100940 Ku70 subunit middle domain
1 1 SCOP 100953 DsbA-like
1 1 SCOP 101234 PWI domain
1 1 SCOP 101279 N-terminal domain of adenylylcyclase associated protein, CAP
1 1 SCOP 101354 Putative anticodon-binding domain of alanyl-tRNA synthetase (AlaRS)
1 1 SCOP 101392 Hsp90 co-chaperone CDC37
1 1 SCOP 101407 Mo25 protein
1 1 SCOP 101536 Coatomer appendage domain
1 1 SCOP 101547 ASF1-like
1 1 SCOP 101888 Apyrase
1 1 SCOP 102463 Peptidyl-tRNA hydrolase II
1 1 SCOP 102492 CAF1-like ribonuclease
1 1 SCOP 102547 RbsD-like
1 1 SCOP 102575 NOL1/NOP2/sun
1 1 SCOP 102646 CoaB-like
1 1 SCOP 102766 Imidazole glycerol phosphate dehydratase
1 1 SCOP 102769 ATP-dependent protease Lon (La), catalytic domain
1 1 SCOP 102887 Coproporphyrinogen III oxidase
1 1 SCOP 102928 NifU/IscU domain
1 1 SCOP 103033 Hypothetical protein YwqG
1 1 SCOP 103197 Roadblock/LC7 domain
1 1 SCOP 103264 Chorismate synthase, AroC
1 1 SCOP 103366 Hypothetical protein PH1602
1 1 SCOP 103492 Preprotein translocase SecY subunit
1 1 SCOP 103658 BAR domain
1 1 SCOP 109906 Surp module (SWAP domain)
1 1 SCOP 109953 Glycosyl Hydrolase Family 88
1 1 SCOP 109968 Eukaryotic translation initiation factor 3 subunit 12, eIF3k, N-terminal domain
1 1 SCOP 109994 VPS9 domain
1 1 SCOP 110005 Glycolipid transfer protein, GLTP
1 1 SCOP 110112 Ctag/Cox11
1 1 SCOP 110377 UxuA-like
1 1 SCOP 110388 MoCo biosynthesis proteins
1 1 SCOP 110396 CutC-like
1 1 SCOP 110513 IF2B-like
1 1 SCOP 110582 Indigoidine synthase A-like
1 1 SCOP 110621 YjjX-like
1 1 SCOP 110627 Glucokinase
1 1 SCOP 110636 ROK
1 1 SCOP 110773 Ubiquitin thiolesterase protein OTUB2 (Otubain-2)
1 1 SCOP 110832 Nip7p homolog, N-terminal domain
1 1 SCOP 110917 Peptidyl-tRNA hydrolase domain
1 1 SCOP 110994 eIF-2-alpha, C-terminal domain
1 1 SCOP 111233 YfcE-like
1 1 SCOP 111322 AF1104-like
1 1 SCOP 111348 Rap/Ran-GAP
1 1 SCOP 117019 ATP-dependent DNA ligase DNA-binding domain
1 1 SCOP 117092 Nuclear movement domain
1 1 SCOP 117282 Kelch motif
1 1 SCOP 117372 YicI catalytic domain-like
1 1 SCOP 117375 Glycosyl hydrolases family 35 catalytic domain
1 1 SCOP 117474 WrbA-like
1 1 SCOP 117558 Type II thymidine kinase
1 1 SCOP 117685 AD-003 protein-like
1 1 SCOP 117917 NifU C-terminal domain-like
1 1 SCOP 118076 TRAPP components
1 1 SCOP 118197 YaeB-like
1 1 SCOP 118204 Vacuolar ATP synthase subunit C
1 1 SCOP 140103 ISY1 N-terminal domain-like
1 1 SCOP 140222 SWIRM domain
1 1 SCOP 140384 BSD domain
1 1 SCOP 140769 MioX-like
1 1 SCOP 140865 TROVE domain-like
1 1 SCOP 140960 Bacterial tryptophan 2,3-dioxygenase
1 1 SCOP 140963 Indoleamine 2,3-dioxygenase-like
1 1 SCOP 140985 PTPA-like
1 1 SCOP 141439 Necap1 N-terminal domain-like
1 1 SCOP 141628 AlkB-like
1 1 SCOP 141755 PdxS-like
1 1 SCOP 141819 PP1699/LP2961-like
1 1 SCOP 141840 Class-II DAHP synthetase
1 1 SCOP 142020 Nqo1 FMN-binding domain-like
1 1 SCOP 142183 Pyrimidine 5'-nucleotidase (UMPH-1)
1 1 SCOP 142186 Enolase-phosphatase E1
1 1 SCOP 142191 5' nucleotidase-like
1 1 SCOP 142565 RoRNP C-terminal domain-like
1 1 SCOP 142651 Methyltransferase 10 domain
1 1 SCOP 142696 RibA-like
1 1 SCOP 142721 PyrH-like
1 1 SCOP 142867 Phytochelatin synthase
1 1 SCOP 142988 Electron transfer flavoprotein-ubiquinone oxidoreductase-like
1 1 SCOP 143001 TIM44-like
1 1 SCOP 143072 UFC1-like
1 1 SCOP 143091 PTD012-like
1 1 SCOP 143114 NAP-like
1 1 SCOP 143642 LplA-like
1 1 SCOP 143725 Janus/Ocnus
1 1 SCOP 143812 GatB/GatE catalytic domain-like
1 1 SCOP 143916 RNase Z-like
1 1 SCOP 143976 lvD/EDD N-terminal domain-like
1 1 SCOP 144028 Nqo4-like
1 1 SCOP 144031 Nq06-like
1 1 SCOP 144075 DP dimerization segment
1 1 SCOP 144218 CSL zinc finger
1 1 SCOP 158338 Rps19E-like
1 1 SCOP 158703 Sec63 N-terminal domain
1 1 SCOP 158742 Trehalase-like
1 1 SCOP 158782 HAT/Suf repeat
1 1 SCOP 158893 Sec63 C-terminal domain-like
1 1 SCOP 159513 EMG1/NEP1-like
1 1 SCOP 159638 Prp8 beta-finger domain-like
1 1 SCOP 159697 TRM1-like
1 1 SCOP 161204 Zf-UBP

The following families have one or more weak hits: