Family Assignments

Domains Proteins SCOP Link Families
11 10 SCOP 52592 G proteins
10 10 SCOP 52375 Class I aminoacyl-tRNA synthetases (RS), catalytic domain
9 9 SCOP 50282 Cold shock DNA-binding domain-like
9 9 SCOP 55682 Class II aminoacyl-tRNA synthetase (aaRS)-like, catalytic domain
9 6 SCOP 81268 Tandem AAA-ATPase domain
9 8 SCOP 81269 Extended AAA-ATPase domain
5 5 SCOP 52686 ABC transporter ATPase domain-like
4 4 SCOP 47324 Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases
4 2 SCOP 53068 Actin/HSP70
4 4 SCOP 53118 DnaQ-like 3'-5' exonuclease
3 3 SCOP 50448 Elongation factors
3 3 SCOP 50678 ValRS/IleRS/LeuRS editing domain
3 2 SCOP 51381 Tryptophan biosynthesis enzymes
3 3 SCOP 51800 Glyceraldehyde-3-phosphate dehydrogenase-like, N-terminal domain
3 2 SCOP 52441 BC N-terminal domain-like
3 3 SCOP 52652 Nitrogenase iron protein-like
3 3 SCOP 54212 Translational machinery components
3 1 SCOP 55980 DNA polymerase III, beta subunit
3 2 SCOP 56067 BC ATP-binding domain-like
2 1 SCOP 48593 GroEL chaperone, ATPase domain
2 2 SCOP 50250 Anticodon-binding domain
2 2 SCOP 50263 Single strand DNA-binding domain, SSB
2 2 SCOP 51231 Biotinyl/lipoyl-carrier proteins and domains
2 2 SCOP 51751 Tyrosine-dependent oxidoreductases
2 2 SCOP 51943 FAD/NAD-linked reductases, N-terminal and central domains
2 2 SCOP 52211 Succinyl-CoA synthetase domains
2 2 SCOP 52318 Class I glutamine amidotransferases (GAT)
2 2 SCOP 52670 RecA protein-like (ATPase-domain)
2 2 SCOP 52923 Transketolase C-terminal domain-like
2 1 SCOP 53080 Acetokinase-like
2 2 SCOP 53138 Ribosomal protein L18 and S11
2 2 SCOP 53402 Cystathionine synthase-like
2 1 SCOP 53902 Thiolase-related
2 2 SCOP 54224 DNA gyrase/MutL, second domain
2 1 SCOP 54229 Ribonuclease PH domain 1-like
2 1 SCOP 54535 FKBP immunophilin/proline isomerase
2 2 SCOP 54815 Prokaryotic type KH domain (KH-domain type II)
2 2 SCOP 55348 GAPDH-like
2 2 SCOP 55879 DNA gyrase/MutL, N-terminal domain
2 1 SCOP 56015 Nitrite and sulphite reductase 4Fe-4S domain-like
2 1 SCOP 56054 Ribosomal protein L6
2 1 SCOP 63783 Riboflavin synthase
2 2 SCOP 75170 DsrEF-like
2 2 SCOP 75459 Pseudouridine synthase RsuA/RluD
2 2 SCOP 75621 Release factor
2 2 SCOP 88735 TK-like Pyr module
2 2 SCOP 88760 TK-like PP module
2 2 SCOP 89572 Biotin dependent carboxylase carboxyltransferase domain
2 1 SCOP 110633 YeaZ-like
1 1 SCOP 46558 GreA transcript cleavage protein, N-terminal domain
1 1 SCOP 46566 Chaperone J-domain
1 1 SCOP 46610 Fe,Mn superoxide dismutase (SOD), N-terminal domain
1 1 SCOP 46907 Ribosomal protein L11, C-terminal domain
1 1 SCOP 46912 Ribosomal protein S18
1 1 SCOP 46947 Ribosomal protein S13
1 1 SCOP 46993 Ribosomal protein S20
1 1 SCOP 47064 Ribosomal protein S15
1 1 SCOP 47253 Ribonucleotide reductase-like
1 1 SCOP 47447 Signal peptide-binding domain
1 1 SCOP 47786 NAD+-dependent DNA ligase, domain 3
1 1 SCOP 47790 C-terminal domain of RNA polymerase alpha subunit
1 1 SCOP 47832 Enzyme I of the PEP:sugar phosphotransferase system HPr-binding (sub)domain
1 1 SCOP 47974 Ribosomal protein S7
1 1 SCOP 48014 Antitermination factor NusB
1 1 SCOP 48020 DNA polymerase III clamp loader subunits, C-terminal domain
1 1 SCOP 48025 N-terminal domain of DnaB helicase
1 1 SCOP 48109 Carbamoyl phosphate synthetase, large subunit connection domain
1 1 SCOP 48169 R1 subunit of ribonucleotide reductase, N-terminal domain
1 1 SCOP 48335 DNA repair protein MutS, domain III
1 1 SCOP 48558 L-aspartase/fumarase
1 1 SCOP 50105 Ribosomal proteins L24p and L21e
1 1 SCOP 50114 C-terminal domain of ribosomal protein L2
1 1 SCOP 50130 GroES
1 1 SCOP 50194 Ribosomal protein L14
1 1 SCOP 50259 DNA helicase RuvA subunit, N-terminal domain
1 1 SCOP 50325 Inorganic pyrophosphatase
1 1 SCOP 50438 NADPH-cytochrome p450 reductase FAD-binding domain-like
1 1 SCOP 50461 Ribosomal protein L3
1 1 SCOP 50466 EF-Tu/eEF-1alpha/eIF2-gamma C-terminal domain
1 1 SCOP 50487 Post formyltransferase domain
1 1 SCOP 50495 Prokaryotic proteases
1 1 SCOP 50716 Ribosomal protein L25-like
1 1 SCOP 50719 Gln-tRNA synthetase (GlnRS), C-terminal (anticodon-binding) domain
1 1 SCOP 51162 UDP N-acetylglucosamine acyltransferase
1 1 SCOP 51247 BC C-terminal domain-like
1 1 SCOP 51284 dUTPase-like
1 1 SCOP 51312 Type 1 signal peptidase
1 1 SCOP 51352 Triosephosphate isomerase (TIM)
1 1 SCOP 51570 Class I aldolase
1 1 SCOP 51591 Class II FBP aldolase
1 1 SCOP 51605 Enolase
1 1 SCOP 51622 Pyruvate kinase
1 1 SCOP 51714 tRNA-guanine transglycosylase
1 1 SCOP 51883 Aminoacid dehydrogenase-like, C-terminal domain
1 1 SCOP 51900 CoA-binding domain
1 1 SCOP 52002 R1 subunit of ribonucleotide reductase, C-terminal domain
1 1 SCOP 52013 N-terminal domain of enzyme I of the PEP:sugar phosphotransferase system
1 1 SCOP 52022 Carbamoyl phosphate synthetase, small subunit N-terminal domain
1 1 SCOP 52030 GroEL-like chaperone, apical domain
1 1 SCOP 52081 Ribosomal proteins L15p and L18e
1 1 SCOP 52097 Clp protease, ClpP subunit
1 1 SCOP 52122 Lumazine synthase
1 1 SCOP 52142 Uracil-DNA glycosylase
1 1 SCOP 52152 FabD-like
1 1 SCOP 52162 Ribosomal protein L13
1 1 SCOP 52167 Ribosomal protein L4
1 1 SCOP 52173 CheY-related
1 1 SCOP 52219 Flavodoxin-related
1 1 SCOP 52231 Cytochrome p450 reductase N-terminal domain-like
1 1 SCOP 52305 Type II 3-dehydroquinate dehydratase
1 1 SCOP 52314 Ribosomal protein S2
1 1 SCOP 52336 Carbamoyl phosphate synthetase, large subunit allosteric, C-terminal domain
1 1 SCOP 52365 NADPH-cytochrome p450 reductase-like
1 1 SCOP 52410 PAPS reductase-like
1 1 SCOP 52491 Tubulin, GTPase domain
1 1 SCOP 52541 Nucleotide and nucleoside kinases
1 1 SCOP 52566 Shikimate kinase (AroK)
1 1 SCOP 52729 PTS IIb component
1 1 SCOP 52778 CAT-like
1 1 SCOP 52901 Glutathione peroxidase-like
1 1 SCOP 52931 Pyruvate-ferredoxin oxidoreductase, PFOR, domain II
1 1 SCOP 52955 Anticodon-binding domain of Class II aaRS
1 1 SCOP 53045 5' to 3' exonuclease catalytic domain
1 1 SCOP 53063 EIIA-man component-like
1 1 SCOP 53099 Ribonuclease H
1 1 SCOP 53134 RuvC resolvase
1 1 SCOP 53151 DNA repair protein MutS, domain II
1 1 SCOP 53179 Peptidyl-tRNA hydrolase-like
1 1 SCOP 53255 Cofactor-dependent phosphoglycerate mutase
1 1 SCOP 53296 Phosphoribosylpyrophosphate synthetase-like
1 1 SCOP 53324 Pyruvate-ferredoxin oxidoreductase, PFOR, domain III
1 1 SCOP 53329 Formyltransferase
1 1 SCOP 53339 RNA methyltransferase FtsJ
1 1 SCOP 53417 GABA-aminotransferase-like
1 1 SCOP 53672 Aspartate/ornithine carbamoyltransferase
1 1 SCOP 53687 Tryptophan synthase beta subunit-like PLP-dependent enzymes
1 1 SCOP 53701 Phosphoglucose isomerase, PGI
1 1 SCOP 53749 Phosphoglycerate kinase
1 1 SCOP 53760 Peptidoglycan biosynthesis glycosyltransferase MurG
1 1 SCOP 53785 Phosphofructokinase
1 1 SCOP 53791 Tetrapyrrole methylase
1 1 SCOP 53851 Phosphate binding protein-like
1 1 SCOP 54190 L23p
1 1 SCOP 54549 GreA transcript cleavage factor, C-terminal domain
1 1 SCOP 54566 Ribosomal protein S16
1 1 SCOP 54571 Ribosomal protein S19
1 1 SCOP 54641 beta-Hydroxydecanol thiol ester dehydrase
1 1 SCOP 54714 Elongation factor Ts (EF-Ts), dimerisation domain
1 1 SCOP 54720 Fe,Mn superoxide dismutase (SOD), C-terminal domain
1 1 SCOP 54737 Ribosomal protein L7/12, C-terminal domain
1 1 SCOP 54748 Ribosomal L11/L12e N-terminal domain
1 1 SCOP 54778 Ribosomal S5 protein, N-terminal domain
1 1 SCOP 54783 Porphobilinogen deaminase (hydroxymethylbilane synthase), C-terminal domain
1 1 SCOP 54822 Ribosomal protein S3 C-terminal domain
1 1 SCOP 54827 Enolase N-terminal domain-like
1 1 SCOP 54844 Ribosomal protein L22
1 1 SCOP 54981 EF-G/eEF-2 domains III and V
1 1 SCOP 54996 Ribosomal protein S6
1 1 SCOP 55000 Ribosomal protein S10
1 1 SCOP 55049 Probable ACP-binding domain of malonyl-CoA ACP transacylase
1 1 SCOP 55121 Pseudouridine synthase I TruA
1 1 SCOP 55125 Duplicated SiR/NiR-like domains 1 and 3
1 1 SCOP 55178 Ribosomal protein S4
1 1 SCOP 55187 Threonyl-tRNA synthetase (ThrRS), second 'additional' domain
1 1 SCOP 55195 Ribosome recycling factor, RRF
1 1 SCOP 55201 Translation initiation factor IF3, C-terminal domain
1 1 SCOP 55258 RNA polymerase alpha subunit dimerisation domain
1 1 SCOP 55262 GAD domain
1 1 SCOP 55272 DNA repair protein MutS, domain I
1 1 SCOP 55283 Ribosomal protein L5
1 1 SCOP 55308 Tubulin, C-terminal domain
1 1 SCOP 55368 Dihydrodipicolinate reductase-like
1 1 SCOP 55376 Glucose 6-phosphate dehydrogenase-like
1 1 SCOP 55425 FAD/NAD-linked reductases, dimerisation (C-terminal) domain
1 1 SCOP 55595 HPr-like
1 1 SCOP 55654 Ribosomal protein L9 C-domain
1 1 SCOP 55667 Ribonuclease PH domain 2-like
1 1 SCOP 55707 Biotin holoenzyme synthetase
1 1 SCOP 55921 Creatinase/aminopeptidase
1 1 SCOP 56038 B3/B4 domain of PheRS, PheT
1 1 SCOP 56048 Ribosomal protein S8
1 1 SCOP 56081 Succinyl-CoA synthetase, beta-chain, N-terminal domain
1 1 SCOP 56096 Adenylation domain of NAD+-dependent DNA ligase
1 1 SCOP 56220 DNase I-like
1 1 SCOP 56323 ADC synthase
1 1 SCOP 56421 Peptide deformylase
1 1 SCOP 56554 Insert subdomain of RNA polymerase alpha subunit
1 1 SCOP 56656 Inositol monophosphatase/fructose-1,6-bisphosphatase-like
1 1 SCOP 56673 DNA polymerase I
1 1 SCOP 56713 Prokaryotic type I DNA topoisomerase
1 1 SCOP 56720 Type II DNA topoisomerase
1 1 SCOP 56732 DNA primase DnaG catalytic core
1 1 SCOP 56809 Ribosomal protein L1
1 1 SCOP 56936 Porin
1 1 SCOP 57752 Ribosomal protein S14
1 1 SCOP 57795 Prokaryotic DNA topoisomerase I, a C-terminal fragment
1 1 SCOP 57939 DnaJ/Hsp40 cysteine-rich domain
1 1 SCOP 58015 Coiled-coil domain of nucleotide exchange factor GrpE
1 1 SCOP 63893 Pyridoxine 5'-phosphate synthase
1 1 SCOP 63976 Pantothenate synthetase (Pantoate-beta-alanine ligase, PanC)
1 1 SCOP 64006 Undecaprenyl diphosphate synthase
1 1 SCOP 64264 Prokaryotic ribosomal protein L17
1 1 SCOP 64485 RNA-polymerase beta
1 1 SCOP 64490 RNA-polymerase beta-prime
1 1 SCOP 69066 RNase III catalytic domain-like
1 1 SCOP 69746 Pseudouridine synthase II TruB
1 1 SCOP 74732 Ribosomal protein L20
1 1 SCOP 74983 Small protein B (SmpB)
1 1 SCOP 75213 YjeE-like
1 1 SCOP 75218 SpoU-like RNA 2'-O ribose methyltransferase
1 1 SCOP 75323 Exonuclease RecJ
1 1 SCOP 75626 YebC-like
1 1 SCOP 81623 N-terminal domain of MutM-like DNA repair proteins
1 1 SCOP 81768 Pre-protein crosslinking domain of SecA
1 1 SCOP 81828 Porin chaperone SurA, peptide-binding domain
1 1 SCOP 81887 Helical scaffold and wing domains of SecA
1 1 SCOP 81924 Double Clp-N motif
1 1 SCOP 82052 Obg GTP-binding protein N-terminal domain
1 1 SCOP 82267 TatD Mg-dependent DNase-like
1 1 SCOP 82336 Shikimate dehydrogenase-like
1 1 SCOP 82359 PP-loop ATPase
1 1 SCOP 82583 G domain-linked domain
1 1 SCOP 82650 SufE-like
1 1 SCOP 82658 BolA-like
1 1 SCOP 88665 Sigma4 domain
1 1 SCOP 88746 PFOR Pyr module
1 1 SCOP 88771 PFOR PP module
1 1 SCOP 88784 rRNA adenine dimethylase-like
1 1 SCOP 88852 SirA-like
1 1 SCOP 88947 Sigma2 domain of RNA polymerase sigma factors
1 1 SCOP 89503 Ketopantoate hydroxymethyltransferase PanB
1 1 SCOP 89629 tRNA(m1G37)-methyltransferase TrmD
1 1 SCOP 89743 N5-glutamine methyltransferase, HemK
1 1 SCOP 89800 Deoxycytidylate deaminase-like
1 1 SCOP 89920 Ribosome-binding factor A, RbfA
1 1 SCOP 90124 ABC transporter transmembrane region
1 1 SCOP 100918 FIS-like
1 1 SCOP 100921 Heat shock protein 70kD (HSP70), peptide-binding domain
1 1 SCOP 101354 Putative anticodon-binding domain of alanyl-tRNA synthetase (AlaRS)
1 1 SCOP 101739 Stringent starvation protein B, SspB
1 1 SCOP 101905 GyrA/ParC C-terminal domain-like
1 1 SCOP 101961 Stabilizer of iron transporter SufD
1 1 SCOP 102401 DNA polymerase III chi subunit
1 1 SCOP 102485 Putative Holliday junction resolvase RuvX
1 1 SCOP 102656 PdxA-like
1 1 SCOP 102663 Phosphotransacetylase
1 1 SCOP 102769 ATP-dependent protease Lon (La), catalytic domain
1 1 SCOP 103026 Aminomethyltransferase folate-binding domain
1 1 SCOP 103132 Predicted metal-dependent hydrolase
1 1 SCOP 109636 DnaK suppressor protein DksA, alpha-hairpin domain
1 1 SCOP 110309 Serine acetyltransferase
1 1 SCOP 110325 Ribosomal L27 protein
1 1 SCOP 111284 Putative modulator of DNA gyrase, PmbA/TldD
1 1 SCOP 111338 QueA-like
1 1 SCOP 111385 OmpH-like
1 1 SCOP 117024 DNA primase DnaG, C-terminal domain
1 1 SCOP 117619 Exodeoxyribonuclease V beta chain (RecB), C-terminal domain
1 1 SCOP 117622 Exodeoxyribonuclease V beta chain (RecC), C-terminal domain
1 1 SCOP 117888 Ribosomal protein L16p
1 1 SCOP 118117 DNA mismatch repair protein MutL
1 1 SCOP 140991 FtsH protease domain-like
1 1 SCOP 141092 Ribosomal protein L21p
1 1 SCOP 141245 Ribosomal protein L19
1 1 SCOP 141256 YccV-like
1 1 SCOP 141723 LON domain-like
1 1 SCOP 142020 Nqo1 FMN-binding domain-like
1 1 SCOP 142611 YhhF-like
1 1 SCOP 143035 Ribosomal protein L35p
1 1 SCOP 143801 Ribosomal protein L28
1 1 SCOP 143804 Ribosomal protein L31p
1 1 SCOP 144028 Nqo4-like
1 1 SCOP 144031 Nq06-like
1 1 SCOP 158443 DsbB-like
1 1 SCOP 159112 RNB domain-like
1 1 SCOP 159832 PBP transglycosylase domain-like

The following families have one or more weak hits: