Family Assignments

Domains Proteins SCOP Link Families
45 45 SCOP 52686 ABC transporter ATPase domain-like
10 9 SCOP 52592 G proteins
10 10 SCOP 55682 Class II aminoacyl-tRNA synthetase (aaRS)-like, catalytic domain
10 7 SCOP 81268 Tandem AAA-ATPase domain
9 9 SCOP 52375 Class I aminoacyl-tRNA synthetases (RS), catalytic domain
7 7 SCOP 53272 Phosphoribosyltransferases (PRTases)
6 5 SCOP 81269 Extended AAA-ATPase domain
5 5 SCOP 52652 Nitrogenase iron protein-like
4 4 SCOP 50282 Cold shock DNA-binding domain-like
4 4 SCOP 52670 RecA protein-like (ATPase-domain)
4 2 SCOP 53068 Actin/HSP70
4 4 SCOP 53204 Bacterial dinuclear zinc exopeptidases
4 4 SCOP 53402 Cystathionine synthase-like
4 4 SCOP 53591 Nucleoside hydrolase
4 4 SCOP 53823 L-arabinose binding protein-like
4 4 SCOP 53851 Phosphate binding protein-like
4 4 SCOP 55921 Creatinase/aminopeptidase
4 3 SCOP 69361 Cell wall binding repeat
4 4 SCOP 90124 ABC transporter transmembrane region
3 3 SCOP 48234 Hyaluronate lyase-like catalytic, N-terminal domain
3 3 SCOP 48558 L-aspartase/fumarase
3 3 SCOP 50006 Hyaluronate lyase-like, central domain
3 3 SCOP 50448 Elongation factors
3 3 SCOP 50678 ValRS/IleRS/LeuRS editing domain
3 3 SCOP 51570 Class I aldolase
3 3 SCOP 51830 Formate/glycerate dehydrogenases, NAD-domain
3 3 SCOP 52541 Nucleotide and nucleoside kinases
3 2 SCOP 53080 Acetokinase-like
3 3 SCOP 53417 GABA-aminotransferase-like
3 3 SCOP 53614 Ribokinase-like
3 3 SCOP 55425 FAD/NAD-linked reductases, dimerisation (C-terminal) domain
3 3 SCOP 55879 DNA gyrase/MutL, N-terminal domain
3 1 SCOP 55974 S-adenosylmethionine synthetase
3 3 SCOP 75459 Pseudouridine synthase RsuA/RluD
3 3 SCOP 82550 DegV-like
3 3 SCOP 88766 Branched-chain alpha-keto acid dehydrogenase PP module
3 3 SCOP 101340 HD domain
3 3 SCOP 161099 MetI-like
2 2 SCOP 50892 Cyclophilin (peptidylprolyl isomerase)
2 1 SCOP 51231 Biotinyl/lipoyl-carrier proteins and domains
2 2 SCOP 51262 Glucose permease-like
2 2 SCOP 51375 Decarboxylase
2 2 SCOP 51413 Inosine monophosphate dehydrogenase (IMPDH)
2 2 SCOP 51431 Aldo-keto reductases (NADP)
2 2 SCOP 51751 Tyrosine-dependent oxidoreductases
2 2 SCOP 51848 LDH N-terminal domain-like
2 2 SCOP 51883 Aminoacid dehydrogenase-like, C-terminal domain
2 2 SCOP 51943 FAD/NAD-linked reductases, N-terminal and central domains
2 2 SCOP 52318 Class I glutamine amidotransferases (GAT)
2 2 SCOP 52729 PTS IIb component
2 2 SCOP 52778 CAT-like
2 2 SCOP 52926 Branched-chain alpha-keto acid dehydrogenase beta-subunit, C-terminal-domain
2 1 SCOP 53089 Glycerol kinase
2 2 SCOP 53138 Ribosomal protein L18 and S11
2 2 SCOP 53168 Purine and uridine phosphorylases
2 2 SCOP 53721 ALDH-like
2 1 SCOP 53902 Thiolase-related
2 1 SCOP 53914 Chalcone synthase-like
2 2 SCOP 54212 Translational machinery components
2 1 SCOP 54229 Ribonuclease PH domain 1-like
2 2 SCOP 54815 Prokaryotic type KH domain (KH-domain type II)
2 1 SCOP 54981 EF-G/eEF-2 domains III and V
2 2 SCOP 55299 YjgF/L-PSP
2 2 SCOP 55470 NADH oxidase/flavin reductase
2 2 SCOP 56248 Penicillin V acylase
2 2 SCOP 56350 Lambda integrase-like, catalytic core
2 2 SCOP 56656 Inositol monophosphatase/fructose-1,6-bisphosphatase-like
2 2 SCOP 56720 Type II DNA topoisomerase
2 2 SCOP 68901 Cytidylytransferase
2 1 SCOP 74656 CoA transferase alpha subunit-like
2 2 SCOP 75218 SpoU-like RNA 2'-O ribose methyltransferase
2 2 SCOP 75621 Release factor
2 2 SCOP 88741 Branched-chain alpha-keto acid dehydrogenase Pyr module
2 2 SCOP 100888 Lesion bypass DNA polymerase (Y-family), catalytic domain
2 2 SCOP 101905 GyrA/ParC C-terminal domain-like
2 2 SCOP 102945 RelA/SpoT domain
2 2 SCOP 110354 Outer surface protein, N-terminal domain
2 2 SCOP 117362 NanE-like
2 2 SCOP 142721 PyrH-like
2 2 SCOP 143642 LplA-like
1 1 SCOP 46566 Chaperone J-domain
1 1 SCOP 46610 Fe,Mn superoxide dismutase (SOD), N-terminal domain
1 1 SCOP 46907 Ribosomal protein L11, C-terminal domain
1 1 SCOP 46947 Ribosomal protein S13
1 1 SCOP 47064 Ribosomal protein S15
1 1 SCOP 47253 Ribonucleotide reductase-like
1 1 SCOP 47324 Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases
1 1 SCOP 47786 NAD+-dependent DNA ligase, domain 3
1 1 SCOP 47918 C-terminal domain of alpha and beta subunits of F1 ATP synthase
1 1 SCOP 47974 Ribosomal protein S7
1 1 SCOP 48151 Endonuclease III
1 1 SCOP 48154 Mismatch glycosylase
1 1 SCOP 48180 Hydroxyisobutyrate and 6-phosphogluconate dehydrogenase domain
1 1 SCOP 48335 DNA repair protein MutS, domain III
1 1 SCOP 48577 Isoprenyl diphosphate synthases
1 1 SCOP 50114 C-terminal domain of ribosomal protein L2
1 1 SCOP 50194 Ribosomal protein L14
1 1 SCOP 50200 Staphylococcal nuclease
1 1 SCOP 50250 Anticodon-binding domain
1 1 SCOP 50461 Ribosomal protein L3
1 1 SCOP 50466 EF-Tu/eEF-1alpha/eIF2-gamma C-terminal domain
1 1 SCOP 50495 Prokaryotic proteases
1 1 SCOP 50940 Sialidases (neuraminidases)
1 1 SCOP 51168 Galactoside acetyltransferase-like
1 1 SCOP 51171 GlmU C-terminal domain-like
1 1 SCOP 51191 Type I phosphomannose isomerase
1 1 SCOP 51352 Triosephosphate isomerase (TIM)
1 1 SCOP 51396 FMN-linked oxidoreductases
1 1 SCOP 51420 Alanine racemase-like, N-terminal domain
1 1 SCOP 51521 Family 1 of glycosyl hydrolase
1 1 SCOP 51591 Class II FBP aldolase
1 1 SCOP 51605 Enolase
1 1 SCOP 51622 Pyruvate kinase
1 1 SCOP 51629 Pyruvate phosphate dikinase, C-terminal domain
1 1 SCOP 51659 Endonuclease IV
1 1 SCOP 51691 NadC C-terminal domain-like
1 1 SCOP 51714 tRNA-guanine transglycosylase
1 1 SCOP 51736 Alcohol dehydrogenase-like, C-terminal domain
1 1 SCOP 51800 Glyceraldehyde-3-phosphate dehydrogenase-like, N-terminal domain
1 1 SCOP 51868 6-phosphogluconate dehydrogenase-like, N-terminal domain
1 1 SCOP 51999 PFL-like
1 1 SCOP 52005 Class III anaerobic ribonucleotide reductase NRDD subunit
1 1 SCOP 52010 Pyruvate phosphate dikinase, central domain
1 1 SCOP 52030 GroEL-like chaperone, apical domain
1 1 SCOP 52081 Ribosomal proteins L15p and L18e
1 1 SCOP 52162 Ribosomal protein L13
1 1 SCOP 52167 Ribosomal protein L4
1 1 SCOP 52173 CheY-related
1 1 SCOP 52297 L-alanine dehydrogenase-like
1 1 SCOP 52314 Ribosomal protein S2
1 1 SCOP 52325 DJ-1/PfpI
1 1 SCOP 52394 Cytidylyltransferase
1 1 SCOP 52403 N-type ATP pyrophosphatases
1 1 SCOP 52419 Nucleoside phosphorylase/phosphoribosyltransferase catalytic domain
1 1 SCOP 52491 Tubulin, GTPase domain
1 1 SCOP 52508 Homo-oligomeric flavin-containing Cys decarboxylases, HFCD
1 1 SCOP 52513 NagB-like
1 1 SCOP 52584 Phosphoribulokinase/pantothenate kinase
1 1 SCOP 52744 Subtilases
1 1 SCOP 52901 Glutathione peroxidase-like
1 1 SCOP 52923 Transketolase C-terminal domain-like
1 1 SCOP 52955 Anticodon-binding domain of Class II aaRS
1 1 SCOP 52973 ITPase (Ham1)
1 1 SCOP 52976 Maf-like
1 1 SCOP 53099 Ribonuclease H
1 1 SCOP 53179 Peptidyl-tRNA hydrolase-like
1 1 SCOP 53183 Pyrrolidone carboxyl peptidase (pyroglutamate aminopeptidase)
1 1 SCOP 53235 Tetrahydrofolate dehydrogenase/cyclohydrolase
1 1 SCOP 53240 Malic enzyme N-domain
1 1 SCOP 53255 Cofactor-dependent phosphoglycerate mutase
1 1 SCOP 53296 Phosphoribosylpyrophosphate synthetase-like
1 1 SCOP 53329 Formyltransferase
1 1 SCOP 53384 AAT-like
1 1 SCOP 53461 UDP-glucose pyrophosphorylase
1 1 SCOP 53509 Proline iminopeptidase-like
1 1 SCOP 53629 Folylpolyglutamate synthetase
1 1 SCOP 53634 Carbamate kinase
1 1 SCOP 53640 AraD-like aldolase/epimerase
1 1 SCOP 53672 Aspartate/ornithine carbamoyltransferase
1 1 SCOP 53687 Tryptophan synthase beta subunit-like PLP-dependent enzymes
1 1 SCOP 53698 double-SIS domain
1 1 SCOP 53701 Phosphoglucose isomerase, PGI
1 1 SCOP 53749 Phosphoglycerate kinase
1 1 SCOP 53760 Peptidoglycan biosynthesis glycosyltransferase MurG
1 1 SCOP 53763 UDP-N-acetylglucosamine 2-epimerase
1 1 SCOP 53785 Phosphofructokinase
1 1 SCOP 53811 TroA-like
1 1 SCOP 54002 Papain-like
1 1 SCOP 54224 DNA gyrase/MutL, second domain
1 1 SCOP 54232 GHMP Kinase, N-terminal domain
1 1 SCOP 54535 FKBP immunophilin/proline isomerase
1 1 SCOP 54571 Ribosomal protein S19
1 1 SCOP 54714 Elongation factor Ts (EF-Ts), dimerisation domain
1 1 SCOP 54720 Fe,Mn superoxide dismutase (SOD), C-terminal domain
1 1 SCOP 54811 GMP synthetase C-terminal dimerisation domain
1 1 SCOP 54822 Ribosomal protein S3 C-terminal domain
1 1 SCOP 54827 Enolase N-terminal domain-like
1 1 SCOP 54844 Ribosomal protein L22
1 1 SCOP 55000 Ribosomal protein S10
1 1 SCOP 55069 Peptide methionine sulfoxide reductase
1 1 SCOP 55121 Pseudouridine synthase I TruA
1 1 SCOP 55178 Ribosomal protein S4
1 1 SCOP 55187 Threonyl-tRNA synthetase (ThrRS), second 'additional' domain
1 1 SCOP 55195 Ribosome recycling factor, RRF
1 1 SCOP 55201 Translation initiation factor IF3, C-terminal domain
1 1 SCOP 55209 Enolpyruvate transferase, EPT
1 1 SCOP 55272 DNA repair protein MutS, domain I
1 1 SCOP 55283 Ribosomal protein L5
1 1 SCOP 55308 Tubulin, C-terminal domain
1 1 SCOP 55348 GAPDH-like
1 1 SCOP 55376 Glucose 6-phosphate dehydrogenase-like
1 1 SCOP 55505 Neurolysin-like
1 1 SCOP 55817 5'-nucleotidase (syn. UDP-sugar hydrolase), C-terminal domain
1 1 SCOP 55832 Thymidylate synthase/dCMP hydroxymethylase
1 1 SCOP 55875 Heat shock protein 90, HSP90, N-terminal domain
1 1 SCOP 56038 B3/B4 domain of PheRS, PheT
1 1 SCOP 56048 Ribosomal protein S8
1 1 SCOP 56054 Ribosomal protein L6
1 1 SCOP 56085 Pyruvate phosphate dikinase, N-terminal domain
1 1 SCOP 56096 Adenylation domain of NAD+-dependent DNA ligase
1 1 SCOP 56220 DNase I-like
1 1 SCOP 56236 Class II glutamine amidotransferases
1 1 SCOP 56328 Lactate & malate dehydrogenases, C-terminal domain
1 1 SCOP 56421 Peptide deformylase
1 1 SCOP 56543 Substrate-binding domain of HMG-CoA reductase
1 1 SCOP 56602 beta-Lactamase/D-ala carboxypeptidase
1 1 SCOP 56673 DNA polymerase I
1 1 SCOP 56713 Prokaryotic type I DNA topoisomerase
1 1 SCOP 56732 DNA primase DnaG catalytic core
1 1 SCOP 56802 Acetyl-CoA synthetase-like
1 1 SCOP 56809 Ribosomal protein L1
1 1 SCOP 64006 Undecaprenyl diphosphate synthase
1 1 SCOP 64183 Manganese-dependent inorganic pyrophosphatase (family II)
1 1 SCOP 64186 HPr kinase HprK C-terminal domain
1 1 SCOP 64264 Prokaryotic ribosomal protein L17
1 1 SCOP 64398 Hsp33 domain
1 1 SCOP 64485 RNA-polymerase beta
1 1 SCOP 69066 RNase III catalytic domain-like
1 1 SCOP 69501 DTD-like
1 1 SCOP 69565 Pyridoxal-dependent decarboxylase
1 1 SCOP 69599 mono-SIS domain
1 1 SCOP 69892 Iron-containing alcohol dehydrogenase
1 1 SCOP 69912 Clc chloride channel
1 1 SCOP 74732 Ribosomal protein L20
1 1 SCOP 74756 3-Methyladenine DNA glycosylase I (Tag)
1 1 SCOP 74911 Aldose 1-epimerase (mutarotase)
1 1 SCOP 74983 Small protein B (SmpB)
1 1 SCOP 75041 SelR domain
1 1 SCOP 75264 Glucose-inhibited division protein B (GidB)
1 1 SCOP 75305 Amidase signature (AS) enzymes
1 1 SCOP 75323 Exonuclease RecJ
1 1 SCOP 75626 YebC-like
1 1 SCOP 75648 ABC transporter involved in vitamin B12 uptake, BtuC
1 1 SCOP 81605 PP2C-like
1 1 SCOP 81656 Meta-cation ATPase, catalytic domain P
1 1 SCOP 81664 Calcium ATPase, transmembrane domain M
1 1 SCOP 81768 Pre-protein crosslinking domain of SecA
1 1 SCOP 81887 Helical scaffold and wing domains of SecA
1 1 SCOP 82052 Obg GTP-binding protein N-terminal domain
1 1 SCOP 82261 N-acetylglucosamine-6-phosphate deacetylase, NagA, catalytic domain
1 1 SCOP 82267 TatD Mg-dependent DNase-like
1 1 SCOP 82371 YbeA-like
1 1 SCOP 82388 Predicted hydrolases Cof
1 1 SCOP 82583 G domain-linked domain
1 1 SCOP 82680 N-utilization substance G protein NusG, N-terminal domain
1 1 SCOP 88735 TK-like Pyr module
1 1 SCOP 88760 TK-like PP module
1 1 SCOP 88854 Protein kinases, catalytic subunit
1 1 SCOP 88947 Sigma2 domain of RNA polymerase sigma factors
1 1 SCOP 89494 HMGL-like
1 1 SCOP 89559 NodB-like polysaccharide deacetylase
1 1 SCOP 89624 Ribose/Galactose isomerase RpiB/AlsB
1 1 SCOP 89629 tRNA(m1G37)-methyltransferase TrmD
1 1 SCOP 89800 Deoxycytidylate deaminase-like
1 1 SCOP 90050 AglA-like glucosidase
1 1 SCOP 100921 Heat shock protein 70kD (HSP70), peptide-binding domain
1 1 SCOP 101308 YutG-like
1 1 SCOP 101354 Putative anticodon-binding domain of alanyl-tRNA synthetase (AlaRS)
1 1 SCOP 101822 Aminopeptidase/glucanase lid domain
1 1 SCOP 101995 PA3696/SPS0176-like
1 1 SCOP 102406 MoCo carrier protein-like
1 1 SCOP 102485 Putative Holliday junction resolvase RuvX
1 1 SCOP 102557 rRNA methyltransferase RlmA
1 1 SCOP 102663 Phosphotransacetylase
1 1 SCOP 102755 Hsp90 middle domain
1 1 SCOP 102769 ATP-dependent protease Lon (La), catalytic domain
1 1 SCOP 102772 YigZ N-terminal domain-like
1 1 SCOP 103232 Arginine deiminase
1 1 SCOP 109725 Conserved carboxylase domain
1 1 SCOP 109756 PhoU-like
1 1 SCOP 109953 Glycosyl Hydrolase Family 88
1 1 SCOP 110396 CutC-like
1 1 SCOP 110436 Ornithine cyclodeaminase-like
1 1 SCOP 110520 Methenyltetrahydrofolate synthetase
1 1 SCOP 111233 YfcE-like
1 1 SCOP 111305 Recombination protein RecR
1 1 SCOP 111338 QueA-like
1 1 SCOP 116807 PadR-like
1 1 SCOP 117558 Type II thymidine kinase
1 1 SCOP 117631 RecU-like
1 1 SCOP 117888 Ribosomal protein L16p
1 1 SCOP 118216 Proton glutamate symport protein
1 1 SCOP 140479 LemA-like
1 1 SCOP 140991 FtsH protease domain-like
1 1 SCOP 141190 PhnA-like
1 1 SCOP 141245 Ribosomal protein L19
1 1 SCOP 141837 GatZ-like
1 1 SCOP 142093 ThiI-like
1 1 SCOP 142339 CofD-like
1 1 SCOP 142611 YhhF-like
1 1 SCOP 142635 hypothetical RNA methyltransferase
1 1 SCOP 142647 TrmB-like
1 1 SCOP 142735 DeoB catalytic domain-like
1 1 SCOP 142789 TM0189-like
1 1 SCOP 143438 THUMP domain
1 1 SCOP 143598 YojJ-like
1 1 SCOP 143812 GatB/GatE catalytic domain-like
1 1 SCOP 143857 DeoB insert domain-like
1 1 SCOP 143927 beta-CASP RNA-metabolising hydrolases
1 1 SCOP 144053 Thermophilic metalloprotease (M29)
1 1 SCOP 158600 MgsA/YrvN C-terminal domain-like
1 1 SCOP 158607 AadK C-terminal domain-like
1 1 SCOP 158737 CPF0428-like
1 1 SCOP 159112 RNB domain-like
1 1 SCOP 159436 HI0933 N-terminal domain-like
1 1 SCOP 159444 SP0239-like
1 1 SCOP 159584 PTS system, Fructose specific IIB subunit-like
1 1 SCOP 159832 PBP transglycosylase domain-like
1 1 SCOP 160257 AadK N-terminal domain-like
1 1 SCOP 160620 EF1021 C-terminal domain-like
1 1 SCOP 160644 EF1021-like

The following families have one or more weak hits: